N-[3-(2-carboxyethyl)phenyl]piperidin-1-ylacetamide derivatives and use thereof as activators of soluble guanylate cyclase
US-2015152050-A1 · Jun 4, 2015 · US
US10259776B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10259776-B2 |
| Application number | US-201816001146-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 6, 2018 |
| Priority date | Apr 13, 2011 |
| Publication date | Apr 16, 2019 |
| Grant date | Apr 16, 2019 |
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The present application relates to novel 3-phenylpropionic acid derivatives which carry a branched or cyclic alkyl substituent in the 3-position, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.
Opening claim text (preview).
The invention claimed is: 1. A compound that is (+)-3-(4-Chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}phenyl)-3-cyclopropylpropanoic acid of formula: and salts, solvates and solvates of the salts thereof.
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