Tooth whitening strip

Patent metadata

Field	Value
Publication number	US-10258546-B2
Application number	US-201114344786-A
Country	US
Kind code	B2
Filing date	Sep 14, 2011
Priority date	Sep 14, 2011
Publication date	Apr 16, 2019
Grant date	Apr 16, 2019

Abstract

Described herein are tooth whitening strips comprising a hydratable adhesive film with a first side and a second side, the first side having a granular bleaching ingredient attached thereto in an amount effective to whiten teeth, together with methods of making and using the same.

First claim

What is claimed is:

1. A tooth whitening strip comprising a hydratable adhesive film with a first side and a second side, the first side having a granular bleaching ingredient attached thereto in an amount effective to whiten teeth, wherein the granular bleaching ingredient is attached to a surface of the film, wherein the tooth whitening strip further comprises a backing layer, wherein the backing layer controls dissolution of the hydratable adhesive film; and wherein the whitening strip further comprises
(i) a perhydrolase
(ii) a carboxyl donor, wherein the carboxyl donor is 1,2,3-triacetoxypropane; and
wherein upon use, peroxide released by the granular bleaching ingredient reacts with the carboxyl donor in the presence of the perhydrolase to form a peracid; and
wherein the hydratable adhesive film comprises hydroxypropylmethyl cellulose (HPMC), polyvinyl acetates (PVAc), and a carbomer in a dry weight ratio for HMPC:PVAc:carbomer of 10-20:20-10:1;
wherein the granular bleaching ingredient comprises from 0.01 to 0.1% of the total weight of the hydratable adhesive film and the granular bleaching ingredient attached thereto; and wherein the particle size (D50) of the granular bleaching ingredient is from about 10 to about 500 microns.

2. The tooth whitening strip of claim 1 , wherein the granular bleaching ingredient is coated with or incorporated within a matrix comprising a quickly dissolving material.

3. The tooth whitening strip of claim 1 , wherein the granular bleaching ingredient is selected from solid peroxides, solid peroxide donors, and solid oxygen donors.

4. The tooth whitening strip of claim 1 , wherein the granular bleaching ingredient is selected from peroxide salts or complexes, peroxyphosphate, peroxycarbonate, perborate, peroxysilicate, persulphate salts, calcium peroxyphosphate, sodium perborate, sodium carbonate peroxide, sodium peroxyphosphate, sodium peroxydisulphate, potassium persulfate, hypochlorites, urea peroxide, hydrogen peroxide polymer complexes, hydrogen peroxide-polyvinyl pyrrolidone polymer complexes, metal peroxides, zinc peroxide, calcium peroxide, peracids, phthalimidoperoxyhexanoic acid (P.A.P.), and combinations thereof.

5. The tooth whitening strip of claim 1 , wherein the granular bleaching ingredient comprises urea peroxide.

6. The tooth whitening strip of claim 1 , wherein the granular bleaching ingredient comprises from 0.02 to 0.08% of the total weight of the hydratable adhesive film and a granular bleaching ingredient attached thereto.

7. The tooth whitening strip of claim 1 , wherein the amount of granular bleaching agent on the first side of the hydratable adhesive film is from about 0.001 to about 1 mg/cm 2 .

8. The tooth whitening strip of claim 1 , further comprising an orally acceptable ketone, wherein the ketone is oxidized to the corresponding dioxirane when the strip is used.

9. The tooth whitening strip of claim 1 , wherein the ingredients are present in amounts sufficient to provide, upon mixing, a bleaching agent in an amount and concentration effective to whiten teeth.

10. The tooth whitening strip of claim 1 , wherein the hydratable adhesive film further comprises a plasticizer.

11. The tooth whitening strip of claim 1 , further comprising propylene glycol.

Assignees

• Boyd Thomas
• Xu Guofeng
• Adams Richard
• Pierce Robert
• Miller Steven
• Viscio David
• Colgate Palmolive Co

Inventors

• Boyd Thomas
• Xu Guofeng
• Adams Richard
• Pierce Robert
• Miller Steven
• Viscio David

Classifications

• A61K8/8141

  Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers · CPC title

• A61K8/0208 Primary

  Tissues; Wipes; Patches · CPC title

• A61Q11/00 Primary

  Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title

• A61K2800/87

  Application Devices; Containers; Packaging · CPC title

• A61K8/0245 Primary

  Specific shapes or structures not provided for by any of the groups of A61K8/0241 · CPC title