System and method for fusing chemical detectors

Patent metadata

Field	Value
Publication number	US-10249481-B2
Application number	US-201615190338-A
Country	US
Kind code	B2
Filing date	Jun 23, 2016
Priority date	Aug 30, 2013
Publication date	Apr 2, 2019
Grant date	Apr 2, 2019

Abstract

Two complementary approaches to the science of IMS technology, IMS and differential IMS (DIMS), are combined into a single instrument to provide improvements in interference rejection without sacrificing detection sensitivity. The technology is applicable to, inter alia, the analysis of trace quantities of toxic or otherwise dangerous organic chemical materials. The approach improves both sensitivity and specificity (interference rejection) of field detection instrumentation.

First claim

We claim:

1. A chemical agent detector comprising:
an ionization chamber including dual inlet ports and at least one ion source for generating unfiltered positive and negative ions from at least one sample received therein from a first direction, the ionization chamber further including a first gasket and first bracket on a first side thereof and a second gasket and a second bracket on a second side thereof for attaching to a first and second ion mobility spectrometry cell;
wherein the first ion mobility spectrometry cell is integrated with the ionization chamber via the first gasket and the first bracket for receiving at least a first portion of the unfiltered positive ions emanating therefrom in a second direction;
further wherein the second ion mobility spectrometry cell is integrated with the ionization chamber via the second gasket and the second bracket for receiving at least a first portion of the unfiltered negative ions emanating therefrom in a third direction;
a differential ion mobility spectrometry cell integrated with the ionization chamber for receiving at least a second portion of the unfiltered positive ions and at least a second portion of the unfiltered negative ions emanating therefrom in the first direction,
wherein the dual inlet ports for the sample are located on a front face of the ionization chamber and the differential ion mobility spectrometry cell is located on a back face of the ionization chamber opposite the front face and the first and second ion mobility spectrometry cells are on opposite sides of the ionization chamber and separated thereby, and further wherein the at least a first portion of the unfiltered positive ions and the at least a first portion of the unfiltered negative ions pass directly to the first ion mobility spectrometry cell and the second ion mobility spectrometry cell from the ionization chamber; and
a processor for separately receiving first detection data from the first ion mobility spectrometry cell, second detection data from the second ion mobility spectrometry cell, and third detection data from the differential ion mobility spectrometry cell and processing the first, second and third detection data to determine presence of one or more chemical agents in the sample; and
further wherein an exit port to the differential ion mobility spectrometry cell further includes at least one side port for allowing a first portion of a drift gas to exit prior to entering the differential ion mobility spectrometry cell.

2. The chemical agent detector according to claim 1 , wherein the ionization chamber further includes:
a top face perpendicular to and connecting the front face, back face and first and second sides;
wherein the front face includes the dual input ports for receiving the sample into the ionization chamber, the top face includes at least one input port for receiving the ion source, the first side includes an i/o port for passing the first portion of unfiltered positive ions to the first ion mobility spectrometry cell and receiving drift gas into the ionization chamber from the first ion mobility spectrometry cell, the second side includes an i/o port for passing the first portion of unfiltered negative ions to the second ion mobility spectrometry cell and receiving drift gas into the ionization chamber from the second mobility spectrometry cell, and the back face includes an exit port for passing the second portion of unfiltered positive ions, the second portion of unfiltered negative ions and the drift gas to the differential ion mobility spectrometry cell.

3. The chemical agent detector according to claim 1 , wherein the ion source is a corona discharge source.

4. The chemical agent detector according to claim 1 , further comprising a mass spectrometer interfaced with an output of the differential ion mobility spectrometry cell.

5. The chemical agent detector according to claim 1 , wherein the at least one ion source is a single ion source.

6. The chemical agent detector according to claim 1 , wherein there are two side ports for allowing a first portion of the drift gas to exit prior to entering the differential ion mobility spectrometry cell.

7. The chemical agent detector according to claim 1 , further comprising an indicator selected from the group consisting of audio, visual and tactile indicators for indicating when the sample contains one or more predetermined chemical agents.

8. A hand-held chemical agent detector comprising:
an ionization chamber including dual inlet ports for receiving one or more samples and at least one ion source for generating unfiltered positive and negative ions from the one or more samples, the ionization chamber further including a first gasket and first bracket on a first side thereof and a second gasket and a second bracket on a second side thereof for attaching to a first and second ion mobility spectrometry cell wherein the dimensions of the ionization chamber are less than 1 cm width, 2.5 cm length and 2.0 cm height;
wherein the first and second ion mobility spectrometry cells are integrated with the ionization chamber on opposite sides thereof via the first gasket and first bracket on a first side thereof and the second gasket and the second bracket on a second side thereof for receiving at least a first portion of the unfiltered positive and negative ions therefrom, wherein the dimensions of the first and second ion mobility spectrometry cells are less than 2.5 cm width, 2.0 cm length and 2.5 cm height; and
a differential ion mobility spectrometry cell integrated with the ionization chamber on a third side thereof opposite the dual inlet ports on a fourth side of the ionization chamber for the one or more samples for receiving at least a second portion of the unfiltered positive ions and at least a second portion of the unfiltered negative ions therefrom, wherein the dimensions of the differential ion mobility spectrometry cell are less than 1 cm width, 1.0 cm length and 3.0 cm height, and further wherein the at least a first portion of the unfiltered positive ions and the at least a first portion of the unfiltered negative ions pass directly to the first ion mobility spectrometry cell and the second ion mobility spectrometry cell from the ionization chamber;
the differential ion mobility spectrometry cell including dual side ports for allowing drift gas from the ionization chamber to exit prior to entering the differential ion mobility spectrometry cell.

9. The hand-held chemical agent detector of claim 8 , the ionization chamber further including:
a top face perpendicular to and connecting the first, and second, third and fourth sides;
wherein the fourth side includes the dual input ports for receiving the sample into the ionization chamber, the top face includes at least one input port for receiving the ion source, the first side includes an i/o port for passing the first portion of unfiltered positive ions to the first ion mobility spectrometry cell and receiving drift gas into the ionization chamber from the first ion mobility spectrometry cell, the second side includes an i/o port for passing the first portion of unfiltered negative ions to the second ion mobility spectrometry cell and receiving drift gas into the ionization chamber from the second ion mobility spectrometry cell, and the third side includes an exit port for passing the second portion of unfiltered positive ions, the second portion of unfiltered negative ions and the drift gas to the differential ion mobility spectrometry cell.

10. The hand-held chemical agent detector according to claim 9 , wherein the at least one ion source is a single corona discharge source.

Assignees

• Leidos Inc

Inventors

• Harden Charles Stephen
• Schafer Robert James

Classifications

• G01N27/624

  Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS] · CPC title

• H01J49/0022

  Portable spectrometers, e.g. devices comprising independent power supply, constructional details relating to portability (small scale devices per se H01J49/0013 and H01J49/0018) · CPC title

• H01J49/0013

  Miniaturised spectrometers, e.g. having smaller than usual scale, integrated conventional components · CPC title

• H01J49/004

  Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn · CPC title

• H01J49/009

  Spectrometers having multiple channels, parallel analysis · CPC title