Peptidomimetic macrocycles
US-2017226177-A1 · Aug 10, 2017 · US
US10246491B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10246491-B2 |
| Application number | US-201514843079-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 2, 2015 |
| Priority date | Mar 6, 2013 |
| Publication date | Apr 2, 2019 |
| Grant date | Apr 2, 2019 |
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The present invention provides peptidomimetic macrocycles capable of regulating HIF1α and methods of using such macrocycles for the treatment of diseases.
Opening claim text (preview).
What is claimed is: 1. A peptidomimetic macrocycle having the formula or a pharmaceutically acceptable salt thereof. 2. A peptidomimetic macrocycle having the formula or a pharmaceutically acceptable salt thereof. 3. A peptidomimetic macrocycle having the formula or a pharmaceutically acceptable salt thereof.
Medicinal preparations containing peptides (peptides containing beta-lactam rings A61K31/00; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, A61K31/00; ergot alkaloids of the cyclic peptide type A61K31/48; containing macromolecular compounds having statistically distributed amino acid units A61K31/74; medicinal preparations containing antigens or antibodies A61K39/00; medicinal preparations characterised by the non-active ingredients, e.g. peptides as drug carriers, A61K47/00) · CPC title
the cyclisation not occurring through 2,4-diamino-butanoic acid · CPC title
the modifying agent being an organic compound · CPC title
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