Peptidomimetic macrocycles and use thereof in regulating HIF1alpha

US10246491B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10246491-B2
Application numberUS-201514843079-A
CountryUS
Kind codeB2
Filing dateSep 2, 2015
Priority dateMar 6, 2013
Publication dateApr 2, 2019
Grant dateApr 2, 2019

How to read this patent

A practical reading order for non-experts. Skip the full description unless you need deep technical detail.

  1. Title

    What the patent document calls the invention.

  2. Abstract

    A short plain-language summary of the technical disclosure.

  3. Assignees and inventors

    Who owns or filed the patent and who is credited as inventor.

  4. Key dates

    Filing, priority, publication, and grant dates set the timeline.

  5. First independent claim

    The legal scope of protection — read this for what is actually claimed.

  6. CPC / IPC classifications

    Technology tags used to group this patent with similar filings.

  7. Citations and related patents

    Prior art links and similar publications in this corpus.

Abstract

Official abstract text for this publication.

The present invention provides peptidomimetic macrocycles capable of regulating HIF1α and methods of using such macrocycles for the treatment of diseases.

First claim

Opening claim text (preview).

What is claimed is: 1. A peptidomimetic macrocycle having the formula or a pharmaceutically acceptable salt thereof. 2. A peptidomimetic macrocycle having the formula or a pharmaceutically acceptable salt thereof. 3. A peptidomimetic macrocycle having the formula or a pharmaceutically acceptable salt thereof.

Assignees

Inventors

Classifications

  • Medicinal preparations containing peptides (peptides containing beta-lactam rings A61K31/00; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, A61K31/00; ergot alkaloids of the cyclic peptide type A61K31/48; containing macromolecular compounds having statistically distributed amino acid units A61K31/74; medicinal preparations containing antigens or antibodies A61K39/00; medicinal preparations characterised by the non-active ingredients, e.g. peptides as drug carriers, A61K47/00) · CPC title

  • C07K7/56Primary

    the cyclisation not occurring through 2,4-diamino-butanoic acid · CPC title

  • the modifying agent being an organic compound · CPC title

Patent family

Related publications grouped by family.

External sources

Frequently asked questions

Answers are generated from the same data shown on this page.

What does patent US10246491B2 cover?
The present invention provides peptidomimetic macrocycles capable of regulating HIF1α and methods of using such macrocycles for the treatment of diseases.
Who is the assignee on this patent?
Aileron Therapeutics Inc
What technology area does this patent fall under?
Primary CPC classification C07K7/56. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Apr 02 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 12 related publications on this page (citations in our corpus or others sharing the same primary CPC).