Picolinamide N-oxide compounds with fungicidal activity

Patent metadata

Field	Value
Publication number	US-10244754-B2
Application number	US-201715690840-A
Country	US
Kind code	B2
Filing date	Aug 30, 2017
Priority date	Aug 30, 2016
Publication date	Apr 2, 2019
Grant date	Apr 2, 2019

Abstract

This disclosure relates to picolinamide N-oxides of Formula I and their use as fungicides.

First claim

What is claimed is:

1. A compound of Formula I,

wherein:
R 1 is hydrogen or C 1 -C 5 alkyl, each optionally substituted with 0, 1 or multiple R 6 ;
R 2 is hydrogen, C 1 -C 5 alkyl or cycloalkyl, each optionally substituted with 0, 1 or multiple R 6 ;
R 3 is alkyl, cycloalkyl, aryl or heteroaryl, each optionally substituted with 0, 1 or multiple R 6 ;
R 4 is hydrogen, halo, hydroxyl, alkyl, or alkoxy;
R 5 is alkyl, cycloalkyl, aryl, heteroaryl, alkoxy, aryloxy, heteroaryloxy, each optionally substituted with 0, 1 or multiple R 6 ;
R 6 is hydrogen, alkyl, aryl, acyl, halo, alkoxy, or heterocyclyl, each optionally substituted with 0, 1 or multiple R 7 ;
R 7 is hydrogen, alkyl, aryl, acyl, halo, alkoxy, or heterocyclyl; and
R 8 is hydrogen or C 1 -C 5 alkyl, each optionally substituted with 0, 1 or multiple R 6 .

2. A compound according to claim 1 , wherein R 1 and R 8 are independently hydrogen or C 1 -C 5 alkyl.

3. A compound according to claim 2 , wherein R 2 is C 1 -C 5 alkyl.

4. A compound according to claim 2 , wherein R 3 and R 5 are independently aryl, each optionally substituted with 0, 1, or multiple R 6 .

5. A compound according to claim 2 , wherein R 4 is hydrogen.

6. A compound according to claim 2 , wherein R 1 and R 8 are independently hydrogen or C 1 -C 5 alkyl, R 2 is C 1 -C 5 alkyl, R 3 and R 5 are independently aryl, each optionally substituted with 0, 1, or multiple R 6 , and R 4 is hydrogen.

7. A composition for the control of a fungal pathogen including mixtures of at least one of the compounds of claim 1 and another pesticide including fungicides, insecticides, nematocides, miticides, arthropodicides, bactericides, and combinations thereof.

8. A composition for the control of a fungal pathogen including mixtures of at least one of the compounds of claim 6 and another pesticide including fungicides, insecticides, nematocides, miticides, arthropodicides, bactericides, and combinations thereof.

Assignees

• Dow Agrosciences Llc

Inventors

• Rigoli Jared W
• Meyer Kevin G
• Yao Chenglin
• Loy Brian A
• Sam Brannon

Classifications

• A01N43/40 Primary

  six-membered rings · CPC title

• C07D213/81

  Amides; Imides · CPC title

• C07D213/83

  Thioacids; Thioesters; Thioamides; Thioimides · CPC title

• C07D213/89

  with hetero atoms directly attached to the ring nitrogen atom · CPC title

• A01N43/90

  having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system · CPC title