Anti-adherent composition

Patent metadata

Field	Value
Publication number	US-10238107-B2
Application number	US-201515329653-A
Country	US
Kind code	B2
Filing date	Apr 1, 2015
Priority date	Jul 31, 2014
Publication date	Mar 26, 2019
Grant date	Mar 26, 2019

Abstract

Compositions for inhibiting the attachment of microbes to a biotic or abiotic surface are disclosed. The compositions include a carrier and an effective amount of an anti-adherent agent. The anti-adherent agents include Dimethicone Propyl PG-Betaine, PEG-150/Decyl Alcohol/SMDI Copolymer, Ammonium Acryloyl Dimethyltaurate/Carboxyethyl, Acrylate Crosspolymer, PEG-20 Soy Sterol, PEG/PPG-25/25 Dimethicone, PEG-12 Dimethicone, Dimethicone, Cyclopentasiloxane (and) PEG-12 Dimethicone Crosspolymer, PPG-12-PEG-50 Lanolin, Glycerin (and) Glycine Max (Soybean) Seed Extract, VP/Dimethiconylacrylate/Polycarbamyl/Polyglycol Ester, PEG-10 Sunflower Glycerides, PEG-8 Amodimethicone, PEG/PPG 20/23 Dimethicone Isobutylene/Ethylmaleimide/Hydroxyethylmaleimide Copolymer, Methacryloyl Ethyl Betaine/Acrylates Copolymer, Poloxamer 407, Ethylene Oxide/Propylene Oxide Block Copolymer, PEG-200 Hydrogenated Castor Oil/IPDI Copolymer, PEG-15 Soyamine/IPDI Copolymer Dimer Dilinoleate, Dimethicone PEG-7 Isostearate, PEG-12 Dimethicone, PEG-17 Dimethicone, Polyoxyethylene Polyoxypropylene block copolymer, Polyalkyleneoxide modified silicone copolymer, Disteareth-75 IPDI, and combinations thereof. Various delivery vehicles, including wipes, may be used to deliver the composition to surfaces.

First claim

What is claimed is:

1. A non-antimicrobial composition for inhibiting the attachment of microbes to a surface, the non-antimicrobial composition comprising:
a liquid carrier; and
an effective amount of an anti-adherent agent selected from the group consisting of Dimethicone Propyl PG-Betaine, PEG-150/Decyl Alcohol/SMDI Copolymer, Ammonium Acryloyl Dimethyltaurate/Carboxyethyl Acrylate Crosspolymer, PEG-20 Soy Sterol, PEG/PPG-25/25 Dimethicone, PPG-12-PEG-50 Lanolin, Glycerin (and) Glycine Max (Soybean) Seed Extract, VP/Dimethiconylacrylate/Polycarbamyl/Polyglycol Ester, PEG-10 Sunflower Glycerides, PEG-8 Amodimethicone, PEG/PPG 20/23 Dimethicone, Methacryloyl Ethyl Betaine/Acrylates Copolymer, PEG-200 Hydrogenated Castor Oil/IPDI Copolymer, PEG-15 Soyamine/IPDI Copolymer Dimer Dilinoleate, PEG-17 Dimethicone, and combinations thereof; and
wherein the anti-adherent agent is a non-antimicrobial and is present in the amount of 0.10% to 20% by weight of the composition.

2. The composition of claim 1 wherein the liquid carrier is hydrophilic.

3. The composition of 1 further comprising a humectant selected from the group consisting of glycerin, glycerin derivatives, hyaluronic acid derivatives, betaine derivatives amino acids, amino acid derivatives, glycosaminoglycans, glycols, polyols, sugars, sugar alcohols, hydrogenated starch hydrolysates, hydroxy acids, hydroxy acid derivatives, salts of PCA, and combinations thereof.

4. The composition of claim 1 further comprising a humectant selected from the group consisting of honey, sorbitol, hyaluronic acid, sodium hyaluronate, betaine, lactic acid, citric acid, sodium citrate, glycolic acid, sodium glycolate, sodium lactate, urea, propylene glycol, butylene glycol, pentylene glycol, ethoxydiglycol, methyl gluceth-10, methyl gluceth-20, PEG-2, PEG-4, PEG-5, PEG-6, PEG-7, PEG-8, PEG-9, PEG-10, Propanediol, xylitol, maltitol, and combinations thereof.

5. The composition of claim 1 comprising an emollient.

6. The composition of claim 1 further comprising an emulsifier.

7. The composition of claim 1 wherein the anti-adherent agent reduces the attachment of microbes to a polystyrene surface by at least 0.5 Log of bacteria according to a High Throughput Anti-adherent Test or a Viable Count Anti-adherence Test Method.

8. The composition of claim 1 wherein the anti-adherent agent reduces the attachment of microbes to a polystyrene surface by at least 1 Log of bacteria according to a High Throughput Anti-adherent Test or a Viable Count Anti-adherence Test Method.

9. The composition of claim 1 further comprising a foaming agent.

10. A wipe comprising:
a nonwoven substrate;
an anti-adherent agent composition comprising 0.10% to 20% by total weight of composition of an anti-adherent agent; and
a hydrophilic carrier;
wherein the composition reduces the adherence of S. aureus on a surface by at least 0.5 log according to a High Throughput Anti-adherent Test Method or a Viable Count Anti-adherence Test Method, and
wherein the anti-adherent composition is non-antimicrobial and the anti-adherent agent is selected from the group consisting of Dimethicone Propyl PG-Betaine, PEG-150/Decyl Alcohol/SMDI Copolymer, Ammonium Acryloyl Dimethyltaurate/Carboxyethyl Acrylate Crosspolymer, PEG-20 Soy Sterol, PEG/PPG-25/25 Dimethicone, PPG-12-PEG-50 Lanolin, Glycerin (and) Glycine Max (Soybean) Seed Extract, VP/Dimethiconylacrylate/Polycarbamyl/Polyglycol Ester, PEG-10 Sunflower Glycerides, PEG-8 Amodimethicone, PEG/PPG 20/23 Dimethicone, Methacryloyl Ethyl Betaine/Acrylates Copolymer, PEG-200 Hydrogenated Castor Oil/IPDI Copolymer, PEG-15 Soyamine/IPDI Copolymer Dimer Dilinoleate, PEG-17 Dimethicone, and combinations thereof.

11. The wipe of claim 10 wherein the anti-adherent agent is present in the amount of 0.1% to 10% by total weight of the composition.

12. The wipe of claim 10 wherein the anti-adherent composition further comprises one or more of ingredients selected from the group consisting of a humectant, an emollient, an emulsifier, and any combination thereof.

Assignees

• Kimberly Clark Co

Inventors

• Chaudhary Vinod
• Engelbrecht Kathleen C
• Koenig David W
• Bhatt Divesh
• Vanden Heuvel Amy L
• Wenzel Scott W
• Mundschau Stacy A

Classifications

• C08L71/02 Primary

  Polyalkylene oxides · CPC title

• A61K8/898

  containing nitrogen, e.g. amodimethicone, trimethyl silyl amodimethicone or dimethicone propyl PG-betaine · CPC title

• C08L2203/02

  for biomedical use · CPC title

• A61K8/925

  of animal origin · CPC title

• A61K8/895

  containing silicon bound to unsaturated aliphatic groups, e.g. vinyl dimethicone · CPC title