Sprayable, aqueous alcoholic microbicidal compositions comprising zinc ions

Patent metadata

Field	Value
Publication number	US-10238105-B2
Application number	US-201314410156-A
Country	US
Kind code	B2
Filing date	Jun 28, 2013
Priority date	Jul 2, 2012
Publication date	Mar 26, 2019
Grant date	Mar 26, 2019

Abstract

Disclosed are pressurized surface treatment compositions which impart a microbicidal benefit to treated surfaces which compositions comprise (or in certain preferred embodiments may consist essentially of, or may consist of): a zinc ion source material which releases zinc ions into the treatment composition, preferably a source of Zn ++ ions, at least lower alkyl aliphatic monohydric alcohol which independently of other constituents present exhibits a microbicidal effect, a propellant; and, water. The compositions may further optionally include one or more further optional constituents such as a detersive surfactant and/or minor amounts of one or more constituents which impart one or more advantageous technical or aesthetic benefits to the compositions, including one or more detersive surfactants wherein the compositions have pH of at least 5. The compositions exhibit a microbicidal or germicidal or antimicrobial effect on treated inanimate surfaces and are characterized in exhibiting a microbicidal benefit when tested against one or more challenge microorganisms, preferably against poliovirus type 1 (Sabin) [“PV1”], according to one or more of the following standardized test protocols: ASTM E1052 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension, or ASTM E1053 Standard Test Method to Assess Virucidal Activity of Chemicals Intended for Disinfection of Inanimate, Nonporous Environmental Surfaces, or European Standard Surface Test, EN13697, or AOAC Germicidal Spray Products as Disinfectant Test Method, AOAC Index, 17 th Ed. (2000).

First claim

The invention claimed is:

1. A sprayable, pressurized inanimate surface treatment composition which imparts a microbicidal benefit to treated surfaces which composition comprises:
a zinc ion source material which releases zinc ions into the treatment composition;
ethanol in an amount not in excess of 40% wt. of the composition;
propellant;
water;
optionally, one or more further constituents which impart one or more advantageous technical or aesthetic benefits to the compositions;
wherein the composition has a pH of about 8 to about 11,
wherein the surface treatment composition is characterized in exhibiting at log 10 reduction of poliovirus type 1 (Sabin) (“PV1”) of 3 or more when tested against one or more challenge microorganisms, according to one or more of the following standardized test protocols: ASTM E1053 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension, or ASTM E1053 Standard Test Method to Assess Virucidal Activity of Chemicals Intended for Disinfection of Inanimate, Nonporous Environmental Surfaces, or European Standard Surface Test, EN1369, or AOAC Germicidal Spray Products as Disinfectant Test Method, AOAC Index, 17 th Ed. (2000).

2. A sprayable, pressurized inanimate surface treatment composition which imparts a microbicidal benefit to inanimate surfaces which comprises:
a zinc ion source material which releases zinc ions into the treatment composition;
in excess of 0% wt., and up to but excluding 20% wt. of at least one lower alkyl aliphatic monohydric alcohol;
optionally at least one quaternary ammonium surfactant compound which provides a microbicidal benefit;
propellant;
water;
one or more detersive surfactants;
optionally, one or more further constituents which impart one or more advantageous technical or aesthetic benefits to the compositions;
wherein the composition has a pH of about 8 to about 11,
wherein the surface treatment composition is characterized in exhibiting a log 10 reduction of poliovirus type 1 (Sabin) (“PV1”) of 3 or more when tested against one or more challenge microorganisms, according to one or more of the following standardized test protocols: ASTM E1052 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension, or ASTM E1053 Standard Test Method to Assess Virucidal Activity of Chemicals Intended for Disinfection of Inanimate, Nonporous Environmental Surfaces, or European Standard Surface Test, EN1369, or AOAC Germicidal Spray Products as Disinfectant Test Method, AOAC Index, 17 th Ed. (2000).

3. A sprayable, pressurized inanimate surface treatment composition which imparts a microbicidal benefit to inanimate surfaces which comprises:
a zinc ion source material which releases zinc ions into the treatment composition;
ethanol in an amount not in excess of 40% wt. of the composition;
at least one surfactant, other than a quaternary ammonium surfactant compound which provides a microbicidal benefit;
propellant;
water;
optionally, one or more further constituents which impart one or more advantageous technical or aesthetic benefits to the compositions;
wherein the composition has a pH of about 8 to about 11,
wherein the surface treatment composition is characterized in exhibiting a log 10 reduction of poliovirus type 1 (Sabin) (“PV1”) of 3 or more when tested against one or more challenge microorganisms, according to one or more of the following standardized test protocols: ASTM E1052 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension, or ASTM E1053 Standard Test Method to Assess Virucidal Activity of Chemicals Intended for Disinfection of Inanimate, Nonporous Environmental Surfaces, or European Standard Surface Test, EN1369, or AOAC Germicidal Spray Products as Disinfectant Test Method, AOAC Index, 17 th Ed. (2000).

4. A composition according to claim 1 , wherein in addition to ethanol, at least one further lower alkyl aliphatic monohydric alcohol is additionally present.

5. A composition according to claim 1 wherein ethanol is the sole alcohol present in the composition.

6. A method of controlling the incidence of undesired microorganisms on an inanimate surface, the method comprising the step of:
contacting the inanimate surface which is in need of treatment or upon which the presence of one or more undesirable microorganisms are suspected or are known to be present, with an effective amount of a treatment composition according to claim 1 .

7. A method of controlling the incidence of undesired microorganisms on an inanimate surface, the method comprising the step of:
contacting the inanimate surface which is in need of treatment or upon which the presence of one or more undesirable microorganisms are suspected or are known to be present, with an effective amount of a treatment composition according to claim 2 .

8. A composition according to claim 3 , wherein in addition to ethanol, at least one further lower alkyl aliphatic monohydric alcohol is additionally present.

9. A composition according to claim 3 wherein ethanol is the sole alcohol present in the composition.

10. A composition according to claim 3 , wherein ethanol is present in an amount not in excess of 38% wt.

11. A method of controlling the incidence of undesired microorganisms on an inanimate surface, the method comprising the step of:
contacting the inanimate surface which is in need of treatment or upon which the presence of one or more undesirable microorganisms are suspected or are known to be present, with an effective amount of a treatment composition according to claim 3 .

12. A composition according to claim 1 , wherein the surface treatment composition is characterized in exhibiting at log 10 reduction of poliovirus type 1 (Sabin) (“PV1”) of 3 to ≥5.0 when tested against one or more challenge microorganisms, according to one or more of the following standardized test protocols: ASTM E1052 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension, or ASTM E1053 Standard Test Method to Assess Virucidal Activity of Chemicals Intended for Disinfection of Inanimate, Nonporous Environmental Surfaces, or European Standard Surface Test, EN1369, or AOAC Germicidal Spray Products as Disinfectant Test Method, AOAC Index, 17 th Ed. (2000).

13. A composition according to claim 2 , wherein the surface treatment composition is characterized in exhibiting at log 10 reduction of poliovirus type 1 (Sabin) (“PV1”) of 3 to ≥5.0 when tested against one or more challenge microorganisms, according to one or more of the following standardized test protocols: ASTM E1053 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension, or ASTM E1053 Standard Test Method to Assess Virucidal Activity of Chemicals Intended for Disinfection of Inanimate, Nonporous Environmental Surfaces, or European Standard Surface Test, EN1369, or AOAC Germicidal Spray Products as Disinfectant Test Method, AOAC Index, 17 th Ed. (2000).

14. A composition according to claim 3 , wherein the surface treatment composition is characterized in exhibiting at log 10 reduction of poliovirus type 1 (Sabin) (“PV1”) of 3 to ≥5.0 when tested against one or more challenge microorganisms, according to one or more of the following standardized test protocols: ASTM E1053 Standard Test Method for Efficacy of Antimicrobial Agents against Viruses in Suspension, or ASTM E1053 Standard Test Method to Assess Virucidal Activity of Chemicals Intended for Disinfection of Inanimate, Nonporous Environmental Surfaces, or European Standard Surface Test, EN1369, or AOAC Germicidal Spray Products as Disinfectant

Assignees

• Reckitt Benckiser Llc

Inventors

• Apollo Frank
• Diemer John
• Ijaz Mohammad Khalid
• Zhu Yun-Peng

Classifications

• A01N31/02 Primary

  Acyclic compounds · CPC title

• A01N59/16

  Heavy metals; Compounds thereof · CPC title

• A01N25/00

  Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application {, e.g. seed treatment or sequential application}; Substances for reducing the noxious effect of the active ingredients to organisms other than pests · CPC title

• A01N2300/00

  Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48 · CPC title

• A01N33/12

  Quaternary ammonium compounds · CPC title