Improved radiopharmaceutical delivery system and use thereof for patient infusion
US-2024325628-A1 · Oct 3, 2024 · US
US10232111B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10232111-B2 |
| Application number | US-201414586923-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 30, 2014 |
| Priority date | Dec 31, 2013 |
| Publication date | Mar 19, 2019 |
| Grant date | Mar 19, 2019 |
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Pump includes a motor and a cam shaft coupled to the motor for rotation about a longitudinal axis of the cam shaft. The cam shaft has at least one radially-outward projection defining a helical engagement portion disposed along a length of the cam shaft. A plurality of finger plates are disposed along the length of the cam shaft, each finger plate mounted for movement in a transverse direction relative to the longitudinal axis of the cam shaft. Each finger plate has an aperture defined therein to receive the cam shaft therethrough. Each aperture has a substantially straight edge region and an opposing edge region. Engagement of the helical engagement portion with the substantially flat edge region during rotation of the cam shaft urges the finger plate transversely toward an extended position.
Opening claim text (preview).
The invention claimed is: 1. A peristaltic pump for delivery of a beneficial agent to a user, comprising: a motor; a cam shaft coupled to the motor for rotation about a longitudinal axis of the cam shaft, the cam shaft having a radially-outward projection defining a helical engagement portion disposed continuously along a length of the cam shaft; and a plurality of finger plates disposed along the length of the cam shaft, each finger plate mounted for movement in a transverse direction relative to the longitudinal axis of the cam shaft, each finger plate having an aperture defined therein to receive the cam shaft therethrough, each aperture defined by a substantially straight edge region and an opposing edge region, each finger plate further having a substantially flat surface contacting an adjacent finger plate and a recessed area within and surrounded by the surface, the recessed area being configured to reduce surface friction between the contacting surfaces of the adjacent finger plates; wherein engagement of the helical engagement portion with the substantially straight edge region of each finger plate during rotation of the cam shaft urges the finger plate transversely toward an extended position. 2. The peristaltic pump of claim 1 , wherein each finger plate is free of transverse movement as the helical engagement portion passes along at least a portion of the opposing edge region thereof during rotation of the cam shaft. 3. The peristaltic pump of claim 1 , wherein the opposing edge region comprises an arcuate edge. 4. The peristaltic pump of claim 1 , wherein the recessed area is disposed proximate the aperture of the finger plate. 5. The peristaltic pump of claim 1 , wherein the recessed area is recessed 0.1 mm relative the surface of the finger plate. 6. The peristaltic pump of claim 1 , wherein each finger plate comprises an end surface at an end facing the direction of the transverse movement, and wherein the recessed area is spaced from the end surface. 7. The peristaltic pump of claim 1 , wherein each finger plate comprises an end surface at an end facing the direction of the transverse movement, and wherein the end surfaces of the finger plates together define a contiguous surface facing the direction of the transverse movement. 8. The peristaltic pump of claim 1 , wherein each finger plate is unbiased. 9. The peristaltic pump of claim 1 , wherein each finger plate is biased away from the extended position. 10. The peristaltic pump of claim 1 , wherein the plurality of finger plates are disposed parallel with each other and arranged for sequential movement toward the extended position. 11. The peristaltic pump of claim 1 , further comprising a gap defined between an end plate of the plurality of finger plates and an interior wall of the peristaltic pump, the peristaltic pump further comprising a filler plate disposed within the gap. 12. The peristaltic pump of claim 11 , wherein the filler plate has a different thickness than each of the plurality of finger plates, the different thickness being less than each of the plurality of finger plates. 13. The peristaltic pump of claim 11 , wherein the filler plate has a different thickness than each of the plurality of finger plates, the different thickness being greater than each of the plurality of finger plates. 14. The peristaltic pump of claim 1 , wherein the substantially straight edge region has a thickness greater than the opposing edge region. 15. The peristaltic pump of claim 1 , wherein each finger plate comprises a ceramic material. 16. The peristaltic pump of claim 1 , wherein the camshaft comprises a ceramic material. 17. The peristaltic pump of claim 1 , further comprising one or more bevel gears coupling the motor to the cam shaft. 18. The peristaltic pump of claim 1 , wherein the cam shaft comprises a chamfered portion formed at a radial end of the helical engagement portion. 19. The peristaltic pump of claim 1 , wherein the helical engagement portion extends around the cam shaft greater than one revolution of the helical engagement portion. 20. The peristaltic pump of claim 1 , further comprising: a cassette including a cassette housing with a fluid reservoir defined therein, a delivery tube fluidly coupled with the fluid reservoir, the cassette housing having a cassette base region; and a pump housing having a receiving region to receive the cassette base region, the plurality of finger plates disposed proximate the receiving region. 21. The peristaltic pump of claim 20 , wherein each finger plate compresses a portion of the delivery tube in the extended position. 22. The peristaltic pump of claim 21 , wherein when the cam shaft rotates out of engagement with the substantially straight edge region of each finger plate, the delivery tube is configured to urge the finger plate away from the extended position. 23. The peristaltic pump of claim 21 , wherein the plurality of finger plates are disposed parallel with each other and arranged for sequential movement toward the extended position to sequentially compress the delivery tube to create a vacuum force to draw the beneficial agent from the fluid reservoir. 24. The peristaltic pump of claim 20 , further comprising a beneficial agent contained in the fluid reservoir. 25. The peristaltic pump of claim 21 , wherein the beneficial agent comprises one or more of levodopa and carbidopa. 26. The peristaltic pump of claim 1 , wherein the recessed area is spaced from the substantially straight edge region. 27. The peristaltic pump of claim 26 , wherein the recessed area has a contoured edge having a middle and opposing ends, the middle being spaced further from the substantially straight edge region than the opposing ends are from the substantially straight edge region. 28. The peristaltic pump of claim 4 , wherein the recessed area is disposed between the aperture of the finger plate and an end surface at an end facing the direction of the transverse movement. 29. The peristaltic pump of claim 27 , wherein the contoured edge is configured to strengthen the substantially straight edge region.
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with microprocessors or computers · CPC title
with interchangeable cassettes forming partially or totally the fluid circuit · CPC title
with back-up system in case of failure · CPC title
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