Safening 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid compositions in Brassica species and methods of use thereof

Patent metadata

Field	Value
Publication number	US-10219513-B2
Application number	US-201715609611-A
Country	US
Kind code	B2
Filing date	May 31, 2017
Priority date	Jun 10, 2016
Publication date	Mar 5, 2019
Grant date	Mar 5, 2019

Abstract

Provided herein are safened herbicidal compositions for use in Brassica species susceptible to injury by 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid comprising (a) a herbicidally effective amount of 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid or an agriculturally acceptable salt or ester of thereof, and (b) a safener. The safener can be a herbicide or a herbicide safener capable of safening the Brassica species susceptible to injury by 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid.

First claim

What is claimed is:

1. A safened herbicidal composition for use in Brassica species susceptible to injury by 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid or an agriculturally acceptable salt or ester thereof comprising:
a) a herbicidally effective amount of 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid or an agriculturally acceptable salt or ester thereof; and
b) a first safener comprising a first herbicide capable of safening the 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid, or an agriculturally acceptable salt or ester thereof, to the Brassica species; and
c) a second safener selected from the group consisting of a second herbicide capable of safening and a herbicide safener, wherein the safened herbicidal composition is capable of safening the 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid, or an agriculturally acceptable salt or ester thereof, to the Brassica species; and
d) optionally, wherein the second safener is a second herbicide, a third safener comprising a herbicide safener, wherein the safened herbicidal composition is capable of safening the 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid, or an agriculturally acceptable salt or ester thereof, to the Brassica species.

2. The composition of claim 1 , wherein (a) is benzyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylate.

3. The composition of claim 1 , wherein the first herbicide capable of safening is clopyralid, quinclorac, picloram, aminopyralid, or an agriculturally acceptable salt or ester thereof.

4. The composition of claim 1 , wherein the first herbicide capable of safening is clopyralid or an agriculturally acceptable salt or ester thereof.

5. The composition of claim 4 , wherein the second herbicide capable of safening is quinclorac or an agriculturally acceptable salt or ester thereof.

6. The composition of claim 4 , wherein the second safener is isoxadifen.

7. The composition of claim 5 , wherein the third safener is isoxadifen.

8. The composition of claim 1 , wherein the first herbicide capable of safening is quinclorac or an agriculturally acceptable salt or ester thereof.

9. The composition of claim 8 , wherein the second safener is isoxadifen.

10. The composition of claim 1 , wherein
a) the application rate of 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid or an agriculturally acceptable salt or ester thereof has a range of 2.5 to 10 g ai/ha; and
b) the application rate of the first safener has an application range of 50 to 200 g ai/ha; and
c) the application rate of the second safener has an application range of 5 to 200 g ai/ha.

11. The composition of claim 10 , wherein the application rate of the second safener has range of 5 to 40 g ai/ha.

12. The composition of claim 10 , wherein the application rate of the second safener has a range of 50 to 200 g ai/ha.

13. The composition of claim 10 , wherein the application rate of the third safener has a range of 5 to 40 g ai/ha.

14. The composition of claim 1 , further comprising an agriculturally acceptable adjuvant or carrier.

15. The composition of claim 1 , wherein the Brassica species is 5-enolpyruvylshikimate-3-phosphate (EPSP) synthase inhibitor-tolerant, glutamine synthetase inhibitor-tolerant, synthetic auxin-tolerant, acetyl CoA carboxylase (ACCase) inhibitor-tolerant, acetolactate synthase (ALS) inhibitor-tolerant, 4-hydroxyphenyl-pyruvate dioxygenase (HPPD) inhibitor-tolerant, protoporphyrinogen oxidase (PPO) inhibitor-tolerant, or photosystem II inhibitor-tolerant.

16. The composition of claim 1 , wherein the Brassica species comprises multiple or stacked traits conferring tolerance to multiple chemistries and/or multiple modes of action.

17. The composition of claim 1 , wherein the Brassica species susceptible to injury from 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid or an agriculturally acceptable salt or ester thereof is Chinese kale ( Brassica alboglabra, BRSAG), brown mustard ( Brassica juncea , BRSJU), rutabaga ( Brassica napus var. napobrassica , BRSNA), canola ( Brassica napus , BRSNN), or turnip ( Brassica rapa , BRSRR).

18. The composition of claim 17 , wherein the Brassica species is winter oilseed rape ( Brassica napus , BRSNW), high omega-9 fatty acid canola ( Brassica napus , BRSNN-NEX), or glyphosate tolerant canola ( Brassica napus , RR-BRSNN).

19. A method for safening Brassica species susceptible to injury from 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid or an agriculturally acceptable salt or ester thereof, comprising applying to the Brassica species, and contacting the vegetation, or area adjacent thereto with a herbicidal composition comprising:
a) a herbicidally effective amount of 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid, or an agriculturally acceptable salt or ester thereof; and
b) a first safener comprising a first herbicide capable of safening the 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid, or an agriculturally acceptable salt or ester thereof, to the Brassica species; and
c) a second safener selected from the group consisting of a second herbicide capable of safening and a herbicide safener, wherein the safened herbicidal composition is capable of safening the 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid, or an agriculturally acceptable salt or ester thereof, to the Brassica species; and
d) optionally, wherein the second safener is a second herbicide, a third safener comprising a herbicide safener, wherein the safened herbicidal composition is capable of safening the 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid, or an agriculturally acceptable salt or ester thereof, to the Brassica species.

20. The method of 19 , wherein (a) is benzyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylate.

21. The method of claim 19 , wherein the first herbicide capable of safening is clopyralid, quinclorac, picloram, aminopyralid, or an agriculturally acceptable salt or ester thereof.

22. The method of claim 19 , wherein the first herbicide capable of safening is clopyralid or an agriculturally acceptable salt or ester thereof.

23. The method of claim 22 , wherein the second herbicide capable of safening is quinclorac or an agriculturally acceptable salt or ester thereof.

24. The method of claim 22 , wherein the second safener is isoxadifen.

25. The method of claim 23 , wherein the third safener is isoxadifen.

26. The method of claim 19 , wherein the first herbicide capable of safening is quinclorac or an agriculturally acceptable salt or ester thereof.

27. The method of claim 26 , wherein the second safener is isoxadifen.

28. The method of claim 19 , wherein
a) the application rate of 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)-5-fluoropyridine-2-carboxylic acid or an agriculturally acceptable salt or ester thereof has a range of 2.5 to 10 g ai/ha; and
b) the applicat

Assignees

• Dow Agrosciences Llc

Inventors

• Satchivi Norbert M
• Gast Roger E

Classifications

• C07D215/18

  Halogen atoms or nitro radicals · CPC title

• A01N2300/00

  Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48 · CPC title

• C07C211/52

  the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups · CPC title

• A01N43/40 Primary

  six-membered rings · CPC title

• C07D213/55

  Acids; Esters · CPC title