Perforated tissue matrix
US-2024408277-A1 · Dec 12, 2024 · US
US10214607B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10214607-B2 |
| Application number | US-201615050258-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 22, 2016 |
| Priority date | Dec 28, 2011 |
| Publication date | Feb 26, 2019 |
| Grant date | Feb 26, 2019 |
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The invention provides a cell adhesion inhibitor comprising, as an active ingredient, a polymer comprising a repeating unit having a sulfinyl group in a side chain thereof.
Opening claim text (preview).
The invention claimed is: 1. A surface-modified tool having, on at least a portion of a surface thereof, a polymer comprising a repeating unit represented by the following formula (1): wherein R 3 represents a copolymer unit obtained by copolymerization of an acrylate monomer with a styrene monomer and R 4 represents a monovalent group represented by the following formula (5) which includes one or more hydroxyl groups attached to a sulfinyl group, wherein k 1 is an integer of 1 to 4; k 2 is an integer of 0 to 4; and *** denotes the position of bonding to a sulfur atom in formula (1). 2. The surface-modified tool according to claim 1 , wherein the polymer further comprises a hydrophobic repeating unit. 3. The surface-modified tool according to claim 1 , wherein said surface-modified tool is a biomedical structure. 4. The surface-modified tool according to claim 1 , wherein said surface-modified tool is a microchannel device. 5. A surface-modified apparatus, having on at least a portion of a surface thereof, a polymer comprising a repeating unit represented by the following formula (1): wherein R 3 represents a copolymer unit obtained by copolymerization of an acrylate monomer with a styrene monomer and R 4 represents a monovalent group represented by the following formula (5) which includes one or more hydroxyl groups attached to a sulfinyl group, wherein k 1 is an integer of 1 to 4; k 2 is an integer of 0 to 4; and *** denotes the position of bonding to a sulfur atom in formula (1). 6. The surface-modified apparatus according to claim 5 , wherein the polymer further comprises a hydrophobic repeating unit. 7. The surface-modified apparatus according to claim 5 , wherein said surface-modified apparatus is a biomedical structure. 8. The surface-modified apparatus according to claim 5 , wherein said surface-modified apparatus is a microchannel device.
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