Vaccine for falciparum malaria

US10213502B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10213502-B2
Application numberUS-201715607203-A
CountryUS
Kind codeB2
Filing dateMay 26, 2017
Priority dateDec 2, 2011
Publication dateFeb 26, 2019
Grant dateFeb 26, 2019

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The invention provides compositions and methods for preventing or reducing the severity of malaria.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method of treating P. falciparum malaria in a subject or vaccinating against malaria comprising administering to the subject a composition comprising a purified PfGARP polypeptide antigen comprising the amino acid sequence of SEQ ID NO: 27 or a purified antigenic fragment thereof comprising the amino acid sequence of SEQ ID NO: 26. 2. The method of claim 1 , wherein said purified antigen or antigenic fragment thereof comprising the amino acid sequence of SEQ ID NO: 26 elicits an antibody immune response against PfGARP. 3. The method of claim 1 , wherein said subject is at least about 6-8 weeks of age. 4. The method of claim 1 , wherein said subject is an adolescent female or a female of childbearing age. 5. The method of claim 1 , wherein said composition is administered intramuscularly. 6. The method of claim 1 , further comprising administering a second vaccine. 7. The method of claim 6 , said second vaccine comprises RTS,S (Mosquirix) or MSP-1.

Assignees

Inventors

Classifications

  • characterised by the host/recipient, e.g. newborn with maternal antibodies · CPC title

  • against material not provided for elsewhere {, e.g. haptens, metals, DNA, RNA, amino acids} · CPC title

  • Plasmodium · CPC title

  • A61K39/015Primary

    Hemosporidia antigens, e.g. Plasmodium antigens · CPC title

  • Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues · CPC title

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Frequently asked questions

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What does patent US10213502B2 cover?
The invention provides compositions and methods for preventing or reducing the severity of malaria.
Who is the assignee on this patent?
Rhode Island Hospital, Seattle Biomedical Res Institute
What technology area does this patent fall under?
Primary CPC classification A61K39/015. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Feb 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).