Imaging apparatus for diagnosis and probe

Patent metadata

Field	Value
Publication number	US-10213186-B2
Application number	US-201414488518-A
Country	US
Kind code	B2
Filing date	Sep 17, 2014
Priority date	Mar 29, 2012
Publication date	Feb 26, 2019
Grant date	Feb 26, 2019

Abstract

An imaging apparatus for diagnosis is provided in which a simpler configuration enables an anatomical technique and a physiological technique to be used in combination. The imaging apparatus for diagnosis disclosed herein includes a first calculator for calculating a parameter indicating each deformation degree of measurement slit portions, by using a tomographic image including the measurement slit portions which are disposed at different positions in an axial direction of a probe unit and whose cross-sectional shape is deformed in response to a pressure applied to the probe unit, and a second calculator for calculating a value corresponding to a myocardial fractional flow reserve, based on the calculated parameter.

First claim

What is claimed is:

1. An imaging apparatus for diagnosis comprising:
a probe unit that includes a sheath and a transmitting and receiving unit located in the sheath, the transmitting and receiving unit transmitting and receiving a signal, the transmitting and receiving unit configured to transmit and receive the signal while rotating inside the sheath in a circumferential direction or while rotating in the circumferential direction and moving in an axial direction, the probe unit including a plurality of deformation portions whose respective cross-sectional shape is deformable in response to an external pressure, the plurality of deformation portions being disposed at different positions of the sheath in the axial direction; and
a computer processor configured to:
calculate at least one parameter at each deformation portion which indicates a deformation degree of the respective deformation portions disposed at the different positions in the axial direction, by using a tomographic image including the deformation portions; and
calculate a value corresponding to a myocardial fractional flow reserve, based on the at least one parameter.

2. The imaging apparatus for diagnosis according to claim 1 ,
wherein each of the deformation portions has a rectangular parallelepiped shape having a predetermined length in the axial direction, and has one surface forming a circumferential surface of the probe unit within the respective deformation portion and the one surface has a rigidity lower than that of other surfaces of the respective deformation portion.

3. The imaging apparatus for diagnosis according to claim 2 ,
wherein the at least one parameter indicating the deformation degree of the respective deformation portions is one of the following:
a volume of the deformation portion, an area at a predetermined position of the deformation portion in the axial direction, a height of the surface forming the circumferential surface at the predetermined position of the deformation portion in the axial direction, or a distortion amount of the surface forming the circumferential surface at the predetermined position of the deformation portion in the axial direction.

4. The imaging apparatus for diagnosis according to claim 1 ,
wherein the computer processor is further configured to:
calculate a value corresponding to the myocardial fractional flow reserve as being equal to (X b0 ×X f1 )/(X b1 ×X f0 ), where a parameter under atmospheric pressure P 0 is X f0 and a parameter inside a body lumen is X f1 which are calculated with regard to a deformation portion disposed at a first position, from among the plurality of deformation portions disposed at the different positions in the axial direction, and that a parameter under the atmospheric pressure P 0 is X b0 and the parameter inside the body lumen is X b1 which are calculated with regard to a deformation portion disposed at a second position, from among the plurality of deformation portions disposed at the different positions in the axial direction.

5. The imaging apparatus for diagnosis according to claim 1 , wherein the processor is further configured to:
extract a tomographic image which includes the respective deformation portion; and
calculate respective center positions in the axial direction of the plurality of deformation portions disposed at the different positions in the axial direction, based on the extracted tomographic image, wherein the at least one parameter is calculated by using a tomographic image generated by rotating the transmitting and receiving unit in the circumferential direction when the transmitting and receiving unit is moved to the respective calculated center positions in the axial direction.

6. The imaging apparatus for diagnosis according to claim 5 , wherein the processor is configured to:
generate multiple tomographic images generated by rotating the transmitting and receiving unit in the circumferential direction for a predetermined time period; and
calculate the at least one parameter by using the tomographic image having a greatest deformation degree of the plurality of deformation portions, from among the multiple tomographic images generated by rotating the transmitting and receiving unit in the circumferential direction for the predetermined time period.

7. The imaging apparatus for diagnosis according to claim 1 ,
wherein the plurality of deformation portions are respectively disposed at a first position in the sheath and at a second position on a further proximal side in the axial direction from the first position, and the plurality of deformation portions are disposed at the respective first position and second position in the circumferential direction.

8. The imaging apparatus for diagnosis according to claim 7 , wherein the processor is configured to:
use a parameter indicating a deformation degree of partial deformation portions within the plurality of deformation portions disposed in the circumferential direction.

9. A probe comprising:
a sheath;
a transmitting and receiving unit transmitting and receiving a signal internally positioned in the sheath and configured to transmit the signal to an imaging apparatus for diagnosis to generate a tomographic image by using the signal acquired while rotating inside the sheath in a circumferential direction or while rotating in the circumferential direction and moving in an axial direction; and
a plurality of deformation portions whose respective cross-sectional shape is deformable in response to a pressure applied to the probe, at different positions along the sheath in the axial direction, wherein each deformation portion has a rectangular parallelepiped shape having a predetermined length in the axial direction, and has one surface forming a circumferential surface of the probe within the respective deformation portion, which is configured to have a member having rigidity lower than that of other surfaces of the respective deformation portion.

10. The probe according to claim 9 ,
wherein the plurality of deformation portions are disposed at a first position in the sheath and at a second position on a proximal side in the axial direction from the first position, and the plurality of deformation portions are disposed at the respective first position and second position in the circumferential direction.

11. A method of calculating a myocardial fractional flow reserve using an imaging apparatus for diagnosis, the method comprising:
inserting the imaging apparatus into a body lumen, the imaging apparatus for diagnosis including a probe unit that includes a sheath and a transmitting and receiving unit located in the sheath, the transmitting and receiving unit transmitting and receiving a signal, the transmitting and receiving unit configured to transmit and receive the signal while rotating inside the sheath in a circumferential direction or while rotating in the circumferential direction and moving in an axial direction, the probe unit including a plurality of deformation portions whose respective cross-sectional shape is deformable in response to an external pressure, the plurality of deformation portions being disposed at different positions of the sheath in the axial direction;
calculating at least one parameter which indicates a deformation degree of the respective deformation portions disposed at the different positions in the axial direction, by using a tomographic image including the deformation portions; and
calculating a value corresponding to the myocardial fractional flow reserve, based on the at least one parameter.

12. The method according to claim 11 ,
wherein each of the deformation portions has a rectangular parallelepi

Assignees

• Terumo Corp

Inventors

• Inoue Koichi
• Furuichi Junya

Classifications

• A61B2576/00

  Medical imaging apparatus involving image processing or analysis (A61B1/00009, A61B6/52 and A61B8/52 take precedence) · CPC title

• A61B5/1128

  using image analysis (A61B5/1127 takes precedence) · CPC title

• A61B5/0295 Primary

  using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography · CPC title

• A61B5/0215

  by means inserted into the body · CPC title

• A61B5/02007

  Evaluating blood vessel condition, e.g. elasticity, compliance · CPC title