NSAIDs DERIVATIVES AND USES THEREOF
US-2015376162-A1 · Dec 31, 2015 · US
US10208014B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10208014-B2 |
| Application number | US-201414533114-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 5, 2014 |
| Priority date | Nov 5, 2014 |
| Publication date | Feb 19, 2019 |
| Grant date | Feb 19, 2019 |
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The invention relates to valproic acid derivatives or pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of valproic acid derivatives, and methods for treating or preventing neurological disorders may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of epilepsy, bipolar disorder, migraine, schizophrenia, depression, Alzheimer's disease, cancer, HIV and familial adenomatous polyposis.
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What is claimed is: 1. A compound of: or a pharmaceutically acceptable salt, enantiomer, or stereoisomer thereof.
Monocarboxylic acid esters having at least two carbon-to-carbon double bonds · CPC title
having the hetero atoms in positions 1 and 2, e.g. lipoic acid · CPC title
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