Apparatus and method for real-time tracking of bony structures

Patent metadata

Field	Value
Publication number	US-10201291-B2
Application number	US-201314040609-A
Country	US
Kind code	B2
Filing date	Sep 27, 2013
Priority date	Oct 26, 2012
Publication date	Feb 12, 2019
Grant date	Feb 12, 2019

Abstract

A method for measuring skin thickness. The method includes at a first 3D point on an outer surface of a patient, exposing the first point to near infrared (NIR) energy from an NIR source. The method includes measuring reflected energy emanating near the first 3D point, or beam incident point. The method includes determining a pattern of the reflected energy based on a distance from a center of the reflected energy, wherein the center is approximated by the first 3D point. The method includes determining a skin thickness measurement based on the pattern.

First claim

What is claimed:

1. A method for treatment of a patient, the method comprising:
exposing a first point on an outer surface of said patient's skin to a beam of near infrared (NIR) energy from an NIR source;
receiving and measuring reflected energy at a detector device, said reflected energy from reflection of said beam by said patient's skin at said first point;
generating a pattern of said reflected energy based on a distance from a center of said reflected energy, wherein said center is approximated by said first point;
determining a thickness measurement of said patient's skin at said first point based on said pattern;
repeating, at a plurality of points on said outer surface of said patient's skin other than said first point, said exposing, said receiving and measuring, said generating a pattern, and said determining a thickness measurement, to determine a plurality of thickness measurements including said thickness measurement at said first point;
using at least a subset of said thickness measurements to determine points of a bone surface of said patient;
determining a position of a target in said patient with respect to said bone surface; and
aligning said position of said target and a beam of radiation and exposing said target to said beam of radiation.

2. The method of claim 1 , wherein said NIR energy has a fixed wavelength.

3. The method of claim 1 , wherein said beam of NIR energy comprises multiple collinear laser beams comprising a combination of various wavelengths and various polarizations.

4. The method of claim 1 , wherein said determining a pattern comprises, for each point on said outer surface of said patient's skin including said first point:
defining a respective plurality of concentric rings around said each point;
determining a respective reflected photon accumulated count for each said respective plurality of concentric rings; and
plotting said respective photon accumulated count for each said respective plurality of concentric rings to generate said pattern for said each point.

5. The method of claim 4 , wherein said determining a thickness measurement comprises, for said each point:
comparing said pattern for said each point against a plurality of predefined patterns reflecting thicknesses of skin;
matching said pattern for said each point to a predefined pattern of said plurality of predefined patterns; and
assigning a thickness measurement associated with said predefined pattern to said each point.

6. A method for radiation treatment, said method comprising:
determining positioning of a surface of an object from an in-treatment optical scan of said object, wherein said in-treatment optical scan comprises:
exposing measured points on a surface of said object to a beam of near infrared (NIR) energy from an NIR source; and
receiving and measuring reflected energy at a detector device, said reflected energy from reflection of said beam by said surface;

for each measured point on said surface of said object, determining a corresponding skin thickness based on a pattern of said reflected energy;
for each said measured point on said surface of said object, compensating for the corresponding skin thickness to determine skeletal positioning associated with and underlying each said measured point;
determining a positioning of skeletal anatomy of said object derived from said skeletal positioning for each said measured point;
determining a position of a target in said object with respect to said positioning of said skeletal anatomy; and
exposing said target to a beam of radiation.

7. The method of claim 6 , wherein said compensating for a corresponding skin thickness comprises:
subtracting a corresponding skin thickness from a corresponding surface positioning measurement to determine said skeletal positioning corresponding to a corresponding measured point.

8. The method for treatment of claim 6 , further comprising:
prior to said in-treatment optical scan, performing a base scan to obtain relative positioning of said skeletal anatomy and relative positioning of a surgical target within said skeletal anatomy.

9. The method of claim 6 , wherein said determining a skin thickness further comprises, at each said measured point:
defining a plurality of concentric rings around said measured point; and
determining a reflected photon accumulated count for each of said concentric rings;
plotting photon accumulated counts for each of said concentric rings to generate said pattern;
comparing said pattern of against a plurality of predefined patterns reflecting thicknesses of skin;
matching said pattern to a predefined pattern of said plurality of predefined patterns; and
assigning a thickness measurement associated with said pattern to said measured point.

10. The method of claim 8 , further comprising:
registering said positioning of said skeletal anatomy derived from said in-treatment optical scan and said positioning of said skeletal anatomy derived from said base scan to determine said relative positioning of said surgical target within said treatment system.

11. The method of claim 10 , further comprising:
determining a first identifiable feature on said surface of said object in said base scan, wherein said identifiable feature comprises an associated location on said skeletal anatomy derived from said base scan;
determining a second identifiable feature on said surface of said object derived from said in-treatment optical scan, wherein said second identifiable feature comprises an associated location on said skeletal anatomy derived from said in-treatment optical scan;
matching said first and second identifiable features based on common characteristics; and
registering said positioning of said skeletal anatomy derived from said in-treatment optical scan and said positioning of said skeletal anatomy derived from said base scan using the alignment between said first and second identifiable features.

12. The method of claim 11 , wherein said determining a second identifiable feature on said surface of said object derived from said in-treatment optical scan comprises:
determining said second identifiable feature based on related skin thicknesses or related patterns of reflected signals from measured points associated with said second identifiable feature.

13. The method of claim 11 , wherein said registering said positioning of said skeletal anatomy derived from said in-treatment optical scan and said positioning of said skeletal anatomy derived from said base scan comprises:
determining rotational alignment between both positioning of corresponding skeletal anatomies.

14. The method of claim 8 , further comprising:
performing said in-treatment optical scan on said object on a periodic basis;
updating registration of said positioning of said skeletal anatomy derived from said in-treatment optical scan and said positioning of said skeletal anatomy derived from said base scan based on a current in-treatment optical scan to determine current relative positioning of said surgical target within said treatment system; and
aligning said surgical target and a treatment beam radiation based on said current relative positioning to expose said surgical target to said treatment beam radiation.

15. A system for radiation treatment, said system comprising:
an in-treatment near infrared (NIR) optical scanner operable for exposing points on an outer surface of a patient's skin to a beam of NIR energy from an NIR source;
at least one detector operable for receiving and measuring reflected energies, said reflected energies from reflection of said beam by said pa

Assignees

• Varian Med Sys Inc
• Varian Medical Systems Particle Therapy Gmbh

Inventors

• Adler Jr John R
• Bruder Ralf
• Ernst Floris
• Schweikard Achim

Classifications

• A61B6/505

  for diagnosis of bone · CPC title

• A61B6/501

  for diagnosis of the head, e.g. neuroimaging or craniography · CPC title

• A61B5/0036

  including treatment, e.g., using an implantable medical device, ablating, ventilating · CPC title

• A61B2090/061

  for measuring dimensions, e.g. length · CPC title

• A61B6/032

  Transmission computed tomography [CT] · CPC title