KCNQ2-5 channel activator
US-9809544-B2 · Nov 7, 2017 · US
KCNQ2-5 channel activator
US10196358B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10196358-B2 |
| Application number | US-201715671428-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 8, 2017 |
| Priority date | Oct 24, 2014 |
| Publication date | Feb 5, 2019 |
| Grant date | Feb 5, 2019 |
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- Title
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- Abstract
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- Assignees and inventors
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- First independent claim
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- CPC / IPC classifications
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Abstract
Official abstract text for this publication.
The present invention relates to a compound represented by the general formula (I) (wherein the definition of each group has the same meaning as described in the specification). The compound is useful as preventive and/or therapeutic agent for KCNQ2-5 channel-related diseases.
First claim
Opening claim text (preview).
The invention claimed is: 1. A pharmaceutical composition comprising 1-[(5-chloro-2-pyridinyl)methyl]-3-{2,6-dichloro-4-[(2S)-1,1,1-trifluoro-2-hydroxy-2-propanyl]phenyl}urea, or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. 2. The pharmaceutical composition according to claim 1 , which is a therapeutic agent for dysuria. 3. The pharmaceutical composition according to claim 2 , wherein the dysuria is overactive urinary bladder. 4. A method for treating dysuria, the method comprising: administering an effective amount of 1-[(5-chloro-2-pyridinyl)methyl]-3-{2,6-dichloro-4-[(2S)-1,1,1-trifluoro-2-hydroxy-2-propanyl]phenyl}urea, or a pharmaceutically acceptable salt thereof, to a mammal. 5. The method according to claim 4 , wherein the dysuria is overactive urinary bladder. 6. A pharmaceutical composition comprising 1-[(5-chloro-2-pyridinyl)methyl]-3-{2,6-dichloro-4-[(2 S)-1,1,1-trifluoro-2-hydroxy-2-propanyl]phenyl}urea and a pharmaceutically acceptable carrier. 7. The pharmaceutical composition according to claim 6 , which is a therapeutic agent for a dysuria. 8. The pharmaceutical composition according to claim 7 , wherein the dysuria is overactive urinary bladder. 9. A method for treating dysuria, the method comprising: administering an effective amount of 1-[(5-chloro-2-pyridinyl)methyl]-3-{2,6-dichloro-4-[(2S)-1,1,1-trifluoro-2-hydroxy-2-propanyl]phenyl}urea to a mammal. 10. The method according to claim 9 , wherein the dysuria is overactive urinary bladder. 11. A method for treating overactive urinary bladder, the method comprising: administering an effective amount of 1-[(5-chloro-2-pyridinyl)methyl]-3-{2,6-dichloro-4-[(2S)-1,1,1-trifluoro-2-hydroxy-2-propanyl]phenyl}urea to a mammal.
Assignees
Inventors
Classifications
Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title
Antidiuretics, e.g. drugs for diabetes insipidus (ADH A61P5/10) · CPC title
Antioedematous agents; Diuretics · CPC title
of the bladder · CPC title
Drugs for disorders of the urinary system · CPC title
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Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US10196358B2 cover?
- The present invention relates to a compound represented by the general formula (I) (wherein the definition of each group has the same meaning as described in the specification). The compound is useful as preventive and/or therapeutic agent for KCNQ2-5 channel-related diseases.
- Who is the assignee on this patent?
- Ono Pharmaceutical Co
- What technology area does this patent fall under?
- Primary CPC classification C07C233/26. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Feb 05 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).