Enhanced flexibility neurovascular catheter

Patent metadata

Field	Value
Publication number	US-10183145-B2
Application number	US-201715442393-A
Country	US
Kind code	B2
Filing date	Feb 24, 2017
Priority date	Feb 24, 2016
Publication date	Jan 22, 2019
Grant date	Jan 22, 2019

Abstract

A catheter is provided, such as for distal neurovascular access or aspiration. The catheter includes an elongate flexible body, having a proximal end, a distal end and a side wall defining a central lumen. A distal zone of the side wall includes a tubular inner liner, a tie layer separated from the lumen by the inner liner, a helical coil surrounding the tie layer, adjacent windings of the coil spaced progressively further apart in the distal direction. An outer jacket surrounds the helical coil. The outer jacket is formed from a plurality of tubular segments positioned end to end, coaxially about the coil. The flexural load profile of the catheter as a function of catheter length is configured to provide enhanced distal flexibility while maintaining high backup support.

First claim

What is claimed is:

1. An enhanced flexibility neurovascular catheter, comprising:
an elongate flexible body, having a proximal end, a distal end, a side wall defining a central lumen, and a proximal zone and a distal zone being separated by a transition region extending from the proximal zone to the distal zone, the side wall comprising:
a tubular inner liner;
a tie layer separated from the lumen by the inner liner;
a helical coil surrounding the tie layer and extending a length from the distal end of at least about 20% of the length of the elongate flexible body, the length less than or equal to a length of the distal zone, adjacent windings of the coil spaced progressively further apart in the distal direction;
a tubular braid surrounding the inner liner, the tubular braid being proximal to the helical coil; and
an outer jacket surrounding the helical coil and the tubular braid, the outer jacket having a durometer of no more than about 35 D along the entire length of the distal zone and a durometer of at least about 60 D along an entire length of the proximal zone;

wherein the outer jacket is formed along the transition region from a plurality of tubular segments, the tubular segments each having a durometer between the durometer of the outer jacket along the proximal zone and the durometer of the outer jacket along the distal zone, each of the durometers decreasing in the distal direction, the transition region being no longer than about 5 cm.

2. An enhanced flexibility neurovascular catheter as in claim 1 , wherein the tubular inner liner is formed by dip coating a removable mandrel.

3. An enhanced flexibility neurovascular catheter as in claim 1 , wherein the tubular inner liner comprises polytetrafluoroethylene.

4. An enhanced flexibility neurovascular catheter as in claim 1 , wherein the tie layer comprises polyurethane.

5. An enhanced flexibility neurovascular catheter as in claim 4 , wherein the tie layer has a wall thickness of no more than about 0.005 inches.

6. An enhanced flexibility neurovascular catheter as in claim 4 , wherein the tie layer extends along at least the most distal 20 cm of the flexible body.

7. An enhanced flexibility neurovascular catheter as in claim 1 , wherein the coil comprises a shape memory material.

8. An enhanced flexibility neurovascular catheter as in claim 7 , wherein the coil comprises Nitinol.

9. An enhanced flexibility neurovascular catheter as in claim 8 , wherein the Nitinol comprises an Austenite state at body temperature.

10. An enhanced flexibility neurovascular catheter as in claim 1 , wherein the outer jacket over the transition region and the distal zone is formed from at least five discrete tubular segments.

11. An enhanced flexibility neurovascular catheter as in claim 1 , wherein the outer jacket over the transition region and the distal zone is formed from at least nine discrete tubular segments.

12. An enhanced flexibility neurovascular catheter as in claim 11 , wherein the difference in durometer between a proximal one of the tubular segments and a distal one of the tubular segments of the outer jacket over the transition region and the distal zone is at least about 20 D.

13. An enhanced flexibility neurovascular catheter as in claim 11 , wherein the difference in durometer between a proximal one of the tubular segments and a distal one of the tubular segments of the outer jacket over the transition region and the distal zone is at least about 30 D.

14. An enhanced flexibility neurovascular catheter as in claim 1 , further comprising a tension support for increasing the tension resistance in the distal zone.

15. An enhanced flexibility neurovascular catheter as in claim 14 , wherein the tension support comprises a filament.

16. An enhanced flexibility neurovascular catheter as in claim 1 , wherein the outer jacket comprises at least three tubular segments along the transition region.

17. An enhanced flexibility neurovascular catheter as in claim 1 , wherein the elongate flexible body comprises a constant outer diameter along the length of the transition region.

18. An enhanced flexibility neurovascular catheter as in claim 1 , wherein the distal zone comprises a smaller outer diameter than the proximal zone.

19. An enhanced flexibility neurovascular catheter, comprising:
an elongate flexible body, having a proximal end, a distal end and a side wall defining a central lumen, the sidewall comprising:
a tubular inner liner;
a tie layer separated from the lumen by the inner liner;
a helical coil surrounding the tie layer; and
an outer jacket surrounding the helical coil, the outer jacket formed from a plurality of tubular segments positioned coaxially about the coil;

wherein a proximal zone and a distal zone of the flexible body are separated by a transition region extending from the proximal zone to the distal zone,
the proximal zone comprising a durometer of at least about 60 D along an entire length of the proximal zone;
the distal zone comprising a durometer of no more than about 35 D along an entire length of the distal zone, the length being at least about 15 cm; and
the transition region comprising at least two of the plurality of tubular segments, the at least two segments having durometers between the durometer of the proximal zone and the durometer of the distal zone and which decrease in the distal direction, the transition region being no longer than about 5 cm.

20. An enhanced flexibility neurovascular catheter as in claim 19 , wherein the length of the distal zone is at least about 20 cm.

Assignees

• Incept Llc

Inventors

• Yang Yi
• Khosravi Fred
• Young Lisa M

Classifications

• A61B6/501

  for diagnosis of the head, e.g. neuroimaging or craniography · CPC title

• A61M25/008

  Strength or flexibility characteristics of the catheter tip · CPC title

• A61B6/481

  involving the use of contrast agents · CPC title

• A61B2217/005

  with suction drainage system · CPC title

• A61M25/0009

  Making of catheters or other medical or surgical tubes · CPC title