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US-2024425484-A1 · Dec 26, 2024 · US
5-aryl-1H-pyrrole-3-carbonitrile and a pharmaceutical product using the same
US10173977B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10173977-B2 |
| Application number | US-201614994360-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 13, 2016 |
| Priority date | Feb 25, 2009 |
| Publication date | Jan 8, 2019 |
| Grant date | Jan 8, 2019 |
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- Title
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- Abstract
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Abstract
Official abstract text for this publication.
The present invention provides a production method of a sulfonylpyrrole compound useful as a pharmaceutical product, a production method of an intermediate used for the method, and a novel intermediate. The present invention relates to a method of producing sulfonylpyrrole compound (VIII), which includes reducing compound (III) and hydrolyzing the reduced product to give compound (IV), subjecting compound (IV) to a sulfonylation reaction to give compound (VI), and subjecting compound (VI) to an amination reaction.
First claim
Opening claim text (preview).
The invention claimed is: 1. A compound represented by the formula wherein R 1a is a phenyl group having 1 to 5 substituents selected from the group consisting of (i) a halogen atom and (ii) C 1-6 alkyl optionally substituted by 1 to 5 halogens, or a salt thereof.
Assignees
Inventors
Classifications
- C07D401/12Primary
linked by a chain containing hetero atoms as chain links · CPC title
- C07D207/48Primary
Sulfur atoms · CPC title
Oxygen or sulfur atoms · CPC title
- C07D207/337Primary
Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals · CPC title
having two double bonds between ring members or between ring members and non-ring members · CPC title
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- What does patent US10173977B2 cover?
- The present invention provides a production method of a sulfonylpyrrole compound useful as a pharmaceutical product, a production method of an intermediate used for the method, and a novel intermediate. The present invention relates to a method of producing sulfonylpyrrole compound (VIII), which includes reducing compound (III) and hydrolyzing the reduced product to give compound (IV), subjecti…
- Who is the assignee on this patent?
- Takeda Pharmaceuticals Co
- What technology area does this patent fall under?
- Primary CPC classification C07D401/12. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).