Dialysis solutions comprising organic esters of phosphoric acid

US10172884B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10172884-B2
Application numberUS-201715459478-A
CountryUS
Kind codeB2
Filing dateMar 15, 2017
Priority dateJun 16, 2015
Publication dateJan 8, 2019
Grant dateJan 8, 2019

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

This document relates to bi-carbonate-buffered dialysis solutions with physiological phosphate content and increased stability. The solutions include an organic ester of phosphoric acid, calcium ions and/or magnesium ions, and optionally additional electrolytes, buffers and glucose in physiologically effective concentrations.

First claim

Opening claim text (preview).

What is claimed is: 1. A multi-chamber bag comprising two or more chambers, wherein a first chamber comprises a first solution that comprises one or more of calcium ions and magnesium ions; and a second chamber comprises a second solution that comprises an organic ester of phosphoric acid and bicarbonate ions, and does not contain calcium ions or magnesium ions, wherein the organic ester of phosphoric acid is glycerol orthophosphate. 2. The multi-chamber bag of claim 1 , wherein the first solution further comprises chloride ions, an osmotic agent; and wherein the second solution further comprises sodium ions and chloride ions. 3. The multi-chamber bag of claim 2 , wherein the first solution further comprises potassium ions. 4. The multi-chamber bag of claim 2 , wherein the first solution does not contain bicarbonate ions, organic esters of phosphoric acid, orthophosphate and sodium ions. 5. The multi-chamber bag of claim 2 , wherein the second solution does not contain calcium ions, magnesium ions, potassium ions, and osmotic agents. 6. The multi-chamber bag of claim 1 , wherein the first solution has a pH of about 2.4 to 3.0; and the second solution has a pH of about 7.0 to 7.8.

Assignees

Inventors

Classifications

  • Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock (artificial tears A61P27/04) · CPC title

  • A61K33/42Primary

    Phosphorus; Compounds thereof · CPC title

  • with two or more compartments · CPC title

  • Solutions {(composition of solutions A61K47/00)} · CPC title

  • Bag-type containers · CPC title

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What does patent US10172884B2 cover?
This document relates to bi-carbonate-buffered dialysis solutions with physiological phosphate content and increased stability. The solutions include an organic ester of phosphoric acid, calcium ions and/or magnesium ions, and optionally additional electrolytes, buffers and glucose in physiologically effective concentrations.
Who is the assignee on this patent?
Fresenius Medical Care Deutschland Gmbh
What technology area does this patent fall under?
Primary CPC classification A61K33/42. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jan 08 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).