Cancer therapy system treatment beam progression and method of use thereof

Patent metadata

Field	Value
Publication number	US-10166408-B2
Application number	US-201715823070-A
Country	US
Kind code	B2
Filing date	Nov 27, 2017
Priority date	May 27, 2016
Publication date	Jan 1, 2019
Grant date	Jan 1, 2019

Abstract

The invention comprises a method and apparatus for treating a tumor with positively charged particles, comprising the steps of: (1) transporting the positively charged particles sequentially from an accelerator, along a beam transport path, through a nozzle system, and along a treatment beam path and (2) while scanning the treatment beam path along each of a set of vectors for treating the tumor, on average for the set of vectors, intentionally deviating the treatment beam path from a current vector of the set of vectors off of the current vector by at least one-eighth of a treatment beam diameter at least once for every twenty movements of the treatment beam.

First claim

The invention claimed is:

1. A method for treating a tumor with positively charged particles, comprising the steps of:
transporting the positively charged particles sequentially from an accelerator, along a beam transport path, through a nozzle system, and along a treatment beam path; and
while scanning the treatment beam path along each of a set of vectors for treating the tumor, on average for the set of vectors, intentionally deviating the treatment beam path from a current vector of the set of vectors off of the current vector by at least one-eighth of a treatment beam diameter at least once for every twenty movements of the treatment beam.

2. The method of claim 1 , said step of intentionally deviating the treatment beam path further comprising the step of:
an extraction system altering energy of the positively charged particles.

3. The method of claim 2 , further comprising the step of:
altering an intensity, a number of the positively charged particles per unit time, of the positively charged particles using electrons emitted from an extraction foil upon passage of the positively charged particles through said extraction foil.

4. The method of claim 3 , further comprising the step of:
dithering the positively charged particles off of the current vector using at least one of an x-axis beam direction controller and a y-axis beam direction controller, the x-axis and the y-axis forming a plane within ten degrees of perpendicular to a z-axis of the treatment beam path.

5. The method of claim 1 , further comprising the step of:
intentionally dithering the positively charged particles, away from a tumor voxel on the current vector, at least one-quarter of a beam diameter for at least two percent of treatment voxels in the set of vectors for treating the tumor.

6. The method of claim 5 , said step of intentionally dithering further comprising the step of:
altering a magnetic field crossing a path of the positively charged particles in said nozzle system to change the treatment beam path by the at least one-quarter of the beam diameter.

7. The method of claim 6 , further comprising the step of: altering energy of the positively charged particles for a current treatment tumor voxel relative to energy of the positively charged particles for treatment of an immediately previous tumor voxel using a voltage difference across a gap in a circulation beam path of the positively charged particles in said accelerator.

8. The method of claim 1 , further comprising the step of:
defocusing the positively charged particles for a current tumor voxel relative to a focus of the positively charged particles for treatment of an immediately previous tumor voxel.

9. The method of claim 1 , further comprising the step of:
dithering energy of the positively charged particles by passing the positively charged particles through a non-uniformly thick rotating material.

10. The method of claim 1 , further comprising the step of:
dithering position of the charged particles by selecting a first set of treatment times at full inhalation of a respiration cycle of the patient and a second set of treatment times within one-half second of a start of patient exhalation.

11. The method of claim 1 , further comprising the step of:
moving the treatment beam path toward a first side of a tumor voxel during a first treatment session of the tumor voxel; and
moving the treatment beam path toward a second side of a tumor voxel during a second treatment session of the tumor voxel, the first side opposite the second side.

12. The method of claim 1 , further comprising the step of:
treating a volume of the tumor with a first scan pattern during a first treatment session; and
treating the volume of the tumor with a second scan pattern during a second treatment session, wherein a correlation coefficient on an axis perpendicular to mean direction of the charged particle beam during treatment of the volume between the first day and the second day is less than 0.7.

13. The method of claim 1 , further comprising the step of:
stitching a second trailing path of the beam transport path of a second row of tumor voxels with a first trailing path of the beam transport path of a first row of tumor voxels by repeatedly crossing the treatment beam path over the first trailing path while treating the second row of tumor voxels.

14. An apparatus for treating a tumor with positively charged particles, comprising:
a beam transport path configured to transport the positively charged particles from an accelerator to a nozzle system, the positively charged particles passing along a treatment beam path from said nozzle system toward the tumor during use; and
a beam controller configured to, while scanning the treatment beam path along each of a set of vectors for treating the tumor, intentionally deviate the treatment beam path from a current vector of the set of vectors to a position off of the current vector by at least one-eighth of a treatment beam diameter at least once per twenty movements of the treatment beam.

15. The apparatus of claim 14 , further comprising:
an extraction system configured to control an energy of the positively charged particles to affect an intended position deviation of the treatment beam path in the tumor, said extraction system communicatively linked to said beam controller.

16. The apparatus of claim 15 , further comprising:
a gap in a circulation beam path of the positively charged particles in said accelerator; and
means for applying a voltage difference across the gap to decelerate the positively charged particles, said means for applying a voltage difference comprising a driving radio frequency field controlled by said beam controller.

17. The apparatus of claim 15 , further comprising:
a circulation beam path of the positively charged particles in said accelerator crossing a path gap comprising a gap entrance side and a gap exit side, said beam controller configured to alter an applied voltage difference between said gap entrance side and said gap exit side to alter energy of the positively charged particles.

18. A method for treating a tumor with positively charged particles, comprising the steps of:
transporting the positively charged particles sequentially from an accelerator, along a beam transport path, through a nozzle system, and along a treatment beam path; and
while scanning the treatment beam path along each of a set of vectors for treating the tumor, intentionally dithering the treatment beam path from a center of a current voxel treatment position by at least one-eighth of a treatment beam diameter at least once per twenty movements of the treatment beam.

Assignees

• Michaud Susan L
• Lee W Davis

Inventors

• Michaud Susan L
• Lee W Davis

Classifications

• A61N2005/1074

  Details of the control system, e.g. user interfaces · CPC title

• A61N5/1078

  Fixed beam systems · CPC title

• A61N5/1075

  for testing, calibrating, or quality assurance of the radiation treatment apparatus · CPC title

• A61N5/1081

  Rotating beam systems with a specific mechanical construction, e.g. gantries · CPC title

• A61N2005/1089

  Electrons · CPC title