Contrast agent perfusion adaptive imaging system

Patent metadata

Field	Value
Publication number	US-10159454-B2
Application number	US-201213594943-A
Country	US
Kind code	B2
Filing date	Aug 27, 2012
Priority date	Sep 9, 2011
Publication date	Dec 25, 2018
Grant date	Dec 25, 2018

Abstract

An imaging system selects a medical imaging protocol using a repository of information associating multiple ranges of contrast agent peak time with corresponding different imaging protocols. An imaging protocol comprises a method for acquiring images using an imaging system and using data identifying at least one of (a) an imaging rate within an imaging scan cycle and (b) an interval between imaging scans. A contrast agent peak time comprises a time a contrast agent concentration substantially reaches a peak value in an anatomical region of interest of a patient relative to a time of start of contrast agent injection. A contrast agent peak time detector detects a contrast agent peak time. An imaging processor adaptively selects an imaging protocol from the imaging protocols in response to a comparison of a detected contrast agent peak time with at least one of the plurality of ranges.

First claim

What is claimed is:

1. A computer implemented system for automatically adaptively selecting a medical image acquisition protocol usable by a Computed Tomography (CT) or X-ray imaging system, comprising:
an imaging system of a Computed Tomography (CT) or X-ray imaging system using an initial image acquisition protocol to acquire an image of an anatomical region of interest of a patient using a corresponding predetermined number of scanning cycles during a predetermined scanning time period;
a repository comprising:
(i) an average contrast agent time to peak time period for a sample patient population based on time periods from when contrast agent concentrations substantially reach peak values in anatomical regions of interests of patients in the population relative to start times of contrast agent injections in the patients; and (ii) a plurality of predetermined different image acquisition protocols; each image acquisition protocol adapted to acquire the image of an anatomical region of interest of a patient using a corresponding predetermined number of scanning cycles during a corresponding predetermined scanning time period;

a contrast agent peak time detector to detect a time that a contrast agent concentration substantially reaches a peak value in the anatomical region of interest of the patient; and
an imaging processor to measure and record values associated with radiation attenuation and a presence of the contrast agent in the region of interest of the patient and to: (i) determine a contrast agent time to peak time period from a time of a start of contrast agent injection to the detected contrast agent peak time; (ii) compare, in response to a detection by the peak detector of a time for the contrast agent to peak in the patient region of interest, the contrast agent time to peak time period to the average contrast agent time to peak time period stored in the repository; (iii) determine whether the contrast agent time to peak time period exceeds or is lower than a predetermined difference threshold from the average contrast agent time to peak time period; (iv) adaptively select, in response to determining said detected contrast agent time to peak time period exceeds the predetermined difference threshold of the average contrast agent time to peak time period, a first image acquisition protocol from said plurality of predetermined image acquisition protocols, said first image acquisition protocol adapted to acquire the image of the anatomical region of interest of the patient using at least one of: (1) an extended scanning time period that is greater than the predetermined scanning time period of the initial image acquisition protocol; and (2) a number of scanning cycles that is greater than the predetermined number of scanning cycles of the initial image acquisition protocol; and (v) adaptively select, in response to determining said detected contrast agent time to peak time period is lower than the predetermined threshold of the average contrast agent time to peak time period, a second image acquisition protocol from said plurality of predetermined image acquisition protocols, said second image acquisition protocol adapted to acquire the image of the anatomical region of interest of the patient using at least one of: (1) a scanning time period that is less than the predetermined scanning time period of the initial image acquisition protocol; and (2) a number of scanning cycles that is less than the predetermined number of scanning cycles of the initial image acquisition protocol;
where, in response to the adaptive selection of the first imaging protocol or the second imaging protocol, images of the anatomical region of interest of the patient are acquired by the imaging system of the at least one of the CT or X-ray imaging system using the first imaging protocol or the second imaging protocol, respectively.

2. A system according to claim 1 , wherein said sample patient population comprises a population of patients based on demographic characteristics and medical conditions of the patient.

3. A system according to claim 2 , wherein said demographic characteristics include at least one of: age, weight, gender and pregnancy status.

4. A system according to claim 2 , wherein said medical conditions include at least one of: heart disease, impaired cardiac function and blood pressure.

5. A system according to claim 1 , wherein in response to determining said detected contrast agent time to peak time period exceeds the predetermined difference threshold of the average contrast agent time to peak time period, said imaging processor selects a first image acquisition protocol adapted to cause at least one of the CT, X-ray and other imaging system to acquire the image using an increased time interval between scanning cycles that is greater than a time interval between the scanning cycles used in the initial image acquisition protocol.

6. A system according to claim 1 , wherein in response to determining said detected contrast agent time to peak time period exceeds the predetermined threshold of the average contrast agent time to peak time period, said imaging processor selects a first image acquisition protocol adapted to cause at least one of the CT, X-ray and other imaging system to acquire the image using a reduced X-ray radiation tube voltage that is lower than an initial X-ray radiation tube voltage used in the initial image acquisition protocol.

7. A system according to claim 1 , wherein the image processor is further configured to determine whether the contrast agent time to peak time period is equal to or lies within the predetermined difference threshold from the average contrast agent time to peak time period; and in response to determining said detected contrast agent time to peak time period is equal to or lies within the predetermined difference threshold from the average contrast agent time to peak time period, said imaging processor continues use of the initial image acquisition protocol without change.

8. A system according to claim 1 , wherein in response to predetermined information indicating said patient has a hemi function impairment related condition, said imaging processor adaptively selects an image acquisition protocol from said plurality of predetermined image acquisition protocols adapted to cause at least one of the CT, X-ray and other imaging system to acquire the image of the anatomical region of interest of the patient using an extended scanning time period that is greater than the predetermined scanning time period of the initial image acquisition protocol.

9. A system according to claim 1 , wherein said imaging processor adaptively selects one of said plurality of image acquisition protocols in response to data input parameters of a post processing method.

10. A system according to claim 1 , wherein said imaging processor adaptively selects an image post-processing method in response to selecting one of said plurality of image acquisition protocols and known patient physiological status.

11. A computer implemented system for automatically adaptively selecting a medical image acquisition protocol usable by a Computed Tomography (CT) or X-ray imaging system, comprising:
an imaging system of a Computed Tomography (CT), X-ray or other imaging system using an initial image acquisition protocol to acquire an image of an anatomical region of interest of a patient using a corresponding predetermined number of scanning cycles during a predetermined scanning time period;
a repository comprising:
(i) an average rate of contrast agent concentration change for a sample patient population; and (ii) a plurality of predetermined different image acquisition protocols, each image acquisition protocol

Assignees

• Grant Katharine Lynn Rowley
• Schmidt Bernhard
• Siemens Healthcare Gmbh

Inventors

• Grant Katharine Lynn Rowley
• Schmidt Bernhard

Classifications

• G16H50/30

  for calculating health indices; for individual health risk assessment · CPC title

• A61B6/486

  involving generating temporal series of image data · CPC title

• A61B6/507

  for determination of haemodynamic parameters, e.g. perfusion CT · CPC title

• A61B6/032

  Transmission computed tomography [CT] · CPC title

• A61B6/5217

  extracting a diagnostic or physiological parameter from medical diagnostic data · CPC title