Filtration device and method

Patent metadata

Field	Value
Publication number	US-10155183-B2
Application number	US-201113996604-A
Country	US
Kind code	B2
Filing date	Dec 20, 2011
Priority date	Dec 21, 2010
Publication date	Dec 18, 2018
Grant date	Dec 18, 2018

Abstract

Embodiments of the present invention relate to a filtration device and method for filtering liquids. In conventional devices, a liquid is placed in a vial, and a plunger, having a filter membrane located at one end, is depressed into the vial, causing the liquid to pass through the filter membrane into the interior of the plunger, where it is stored until required for further processing. However, such plungers are typically made of a plastics material. It is undesirable to store the filtered liquid in contact with plastics for extended periods of time, as contaminants may leach from the plastics material into the sample. In embodiments of the present invention, a filtrate receptacle made from a different material to the plunger, such as a glass material, is located in the interior of the plunger and the filtered liquid collected in the filtrate receptacle after passing through the filter membrane. This allows the filtered liquid to be held isolated from the plastics material, thereby protecting it from contamination.

First claim

The invention claimed is:

1. A filtration device for use with a liquid receptacle configured to hold a liquid sample, the liquid receptacle having a closed end for holding said liquid sample, the filtration device comprising:
a plunger body made of a first material, the plunger body comprising an internal chamber;
a filter material; and
a filtrate receptacle within the internal chamber of the plunger body, the filtrate receptacle being made of a second material, the second material being different from the first material, wherein said second material comprises a glass material,
wherein the filtration device is arranged to be slidably movable in the liquid receptacle so that the filter material moves towards said closed end of the liquid receptacle,
wherein said movement causes liquid held in said liquid receptacle to pass through said filter material to the internal chamber of the plunger body, thereby filtering the liquid, the filtered liquid passing into said filtrate receptacle.

2. The filtration device of claim 1 , wherein said second material is more inert than said first material.

3. The filtration device of claim 1 , wherein said second material comprises a ceramic material.

4. The filtration device of claim 1 , wherein the first material comprises a plastics material.

5. The filtration device of claim 1 , wherein said filtrate receptacle comprises opposing open ends, at least one of the open ends being arranged to receive the filtered liquid sample from said filter material.

6. The filtration device of claim 5 , wherein the filtrate receptacle comprises a hollow cylinder open at each end.

7. The filtration device of claim 1 , comprising one or more conduits, the one or more conduits being fluidly connected to said filter material to receive filtered liquid sample therefrom, the one or more conduits being arranged such that filtered liquid passing therethrough is collected in said filtrate receptacle.

8. The filtration device of claim 7 , wherein the one or more conduits comprises a tube extending in the interior of the filtrate receptacle.

9. The filtration device of claim 8 , wherein the filtrate receptacle is substantially cylindrical, and the tube extends along an axis of the filtrate receptacle.

10. The filtration device of claim 7 , wherein the filtrate receptacle comprises an open end and an opposing closed end, the closed end being located facing said filter material, and the one or more conduits extend around a periphery of the filtrate receptacle, thereby fluidly connecting the filter material to said open end.

11. The filtration device of claim 10 , wherein said one or more conduits comprise one or more channels in an internal wall of the plunger body.

12. The filtration device of claim 11 , wherein each of said one or more channels comprises an opening arranged to provide liquid to said filtrate receptacle during said movement, the opening being angled inward from the internal wall so as to direct liquid towards the open end of the filtrate receptacle.

13. The filtration device of claim 12 , comprising a stop portion extending inwards from said internal wall of the plunger body, the stop portion being arranged to limit movement of the filtrate receptacle within said internal chamber, so as to prevent the open end of the filtrate receptacle moving past the stop portion, wherein said stop portion comprises said opening.

14. The filtration device of claim 1 , wherein the plunger body comprises an aperture, the filter material being located at the aperture.

15. The filtration device of claim 14 , comprising:
a cap at an end opposing said aperture, the cap being arranged to provide an air-tight seal to prevent air from passing from said interior chamber to the exterior of the plunger body; and
a vent hole connecting said internal chamber with the exterior of the plunger body, such that air may escape from said internal chamber during said movement.

16. The filtration device of claim 15 , comprising a channel extending in a wall of said internal chamber from a first position inside said internal chamber to said vent hole, the first position being more proximal to the cap than the vent hole.

17. The filtration device of claim 1 , wherein said plunger assembly comprises a sealing means for forming a seal between the plunger assembly and the liquid receptacle during said movement, the seal preventing liquid passing around a periphery of the plunger assembly during said movement.

18. The filtration device of claim 17 , wherein said sealing means comprises a flexible portion, said flexible portion being capable of flexing on insertion into said liquid receptacle to correspond to an internal cross-section of said liquid receptacle, the flexible portion exerting an outward force on an internal wall of the liquid receptacle during said movement, thereby forming said seal.

19. The filtration device of claim 18 , wherein said flexible portion comprises a flexible rib extending outwards from the plunger body, the flexible rib being capable of deflecting longitudinally relative to the plunger body, and inwards towards the plunger body during said movement.

20. The filtration device of claim 18 , wherein said flexible portion comprises a flexible skirt extending downwards from an end of the plunger body, the skirt being deflectable inwards.

21. The filtration device of claim 20 , wherein said skirt forms a wall of a recess portion, the recess portion being arranged to receive liquid during said movement, the received liquid exerting an outward force on said skirt.

22. A filtration apparatus comprising the filtration device of claim 1 and a liquid receptacle.

23. The filtration apparatus of claim 22 , wherein said liquid receptacle is made from a glass material.

24. The filtration apparatus of claim 22 , wherein the liquid receptacle is comprises an open end through which at least part of said plunger assembly may pass, and said open end comprises a tapered portion.

25. A method of filtering a liquid, comprising:
inserting a liquid sample into a liquid receptacle;
inserting a filtration device into the liquid receptacle, the filtration device comprising a plunger body and a filter material, the plunger body being made of a first material and comprising an internal chamber; and
depressing the plunger body into the liquid receptacle, thereby causing the inserted liquid sample to pass through said filter material and into a filtrate receptacle located in said internal chamber, the filtrate receptacle being made of a second material, the second material being different from the first material, wherein said second material comprises a glass material.

Assignees

• Tortorella Stevan Paul
• Pathirana Navin Deepal
• Seymour Geraint
• Ge Healthcare Uk Ltd

Inventors

• Tortorella Stevan Paul
• Pathirana Navin Deepal
• Seymour Geraint

Classifications

• B01L2200/141

  Preventing contamination, tampering · CPC title

• B01D33/01 Primary

  with translationally moving filtering elements, e.g. pistons (B01D33/04 - B01D33/327 take precedence) · CPC title

• B01D29/118

  open-ended · CPC title

• B01L2300/0681

  Filter · CPC title

• B01L3/508

  Rigid containers without fluid transport within · CPC title