Compositions for the treatment of peripheral ulcers of various origins

Patent metadata

Field	Value
Publication number	US-10149877-B2
Application number	US-201615296533-A
Country	US
Kind code	B2
Filing date	Oct 18, 2016
Priority date	Sep 16, 2011
Publication date	Dec 11, 2018
Grant date	Dec 11, 2018

Abstract

The present invention relates to combinations of an agent that stimulates cell proliferation and an anti-inflammatory/analgesic, which are useful in the treatment of peripheral ulcers of various origins, such as radiation dermatitis, diabetic ulcers, ulcers caused by venous stasis of the limbs, bedsores, and the associated skin infections, proctitis, vulvovaginitis and haemorrhoids with vascular lesions. These combinations can be presented as formulations for topical use.

First claim

The invention claimed is:

1. A composition comprising:
a) bisulphite adducts of anthocyanosides from Vaccinium myrtillus,
b) a lipophilic extract of Echinacea sp, wherein the composition contains 0.05 to 2% of said bisulphite adducts and 0.01 to 1% of said lipophilic extract of Echinacea sp.

2. The composition according to claim 1 , wherein the lipophilic extract of Echinacea sp. is a lipophilic extract of Echinacea angustifolia or Echinacea purpurea.

3. The composition according to claim 1 suitable for topical administration.

4. A composition comprising
a) bisulphite adducts of anthocyanosides from Vaccinium myrtillus,
b) anthocyanosides from Vaccinium myrtillus ; and
c) a lipophilic extract of Echinacea sp, wherein the composition contains 0.05 to 2% of said bisulphite adducts and 0.01 to 1% of said lipophilic extract of Echinacea sp.

5. The composition according to claim 4 , wherein the extract of Echinacea sp. is a lipophilic extract of Echinacea angustifolia or Echinacea purpurea.

6. The composition according to claim 4 suitable for topical administration.

Assignees

• Indena Spa

Inventors

• Bombardelli Ezio

Classifications

• A61P9/14

  Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers · CPC title

• A61P3/10

  for hyperglycaemia, e.g. antidiabetics · CPC title

• A61P31/02

  Local antiseptics · CPC title

• A61P31/00

  Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics · CPC title

• A61P29/00

  Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title