Liquid soap having enhanced antibacterial activity

Patent metadata

Field	Value
Publication number	US-10144908-B2
Application number	US-201414784178-A
Country	US
Kind code	B2
Filing date	Apr 9, 2014
Priority date	Apr 16, 2013
Publication date	Dec 4, 2018
Grant date	Dec 4, 2018

Abstract

Method of cleansing human skin employing an aqueous soap composition comprising of fatty acid soap, at least one silver (I) compound having a silver ion solubility (in water at 25° C.) of at least 1×10−4 mol/L, and water, which composition provides biocidal activity against Gram positive bacteria in particular S. aureus, in relatively short contact periods.

First claim

The invention claimed is:

1. A method of reducing Gram positive bacteria comprising Staphylococcus aureus , on human skin which comprises:
a) providing a liquid cleansing formulation comprising:
(i) from 5 to 65% by weight, based on the total weight of the formulation, of fatty acid soaps, wherein the fatty acid soaps are derived from fatty acids comprising lauric acid and oleic acid,
(ii) 0.1 to 100 ppm by weight, based on the total weight of the formulation, of at least one silver(I) compound having a silver ion solubility (in water at 25° C.) of at least 1×10 −4 mol/L; and
(iii) 20 to 90% by weight water;

b) diluting the liquid cleansing formulation to form an aqueous soap composition having a pH in the range of 9 to 11, said aqueous soap composition comprising:
(i) from 0.2 to 25% by weight of the fatty acid soaps;
(ii) said at least one silver(I) compound having a silver ion solubility (in water at 25° C.) of at least 1×10 −4 mol/L;

c) reducing the Staphylococcus aureus present on human skin by applying to the human skin said aqueous soap composition;
d) allowing the aqueous soap composition to remain on the human skin for a contact period of under 1 minute; and
d) rinsing the aqueous soap composition from the human skin.

2. A method as described in claim 1 wherein the silver(I) compound is present in the liquid cleansing formulation in an amount of from 1 to 50 ppm, based on the total weight of the formulation.

3. A method as described in claim 1 wherein the silver compound comprises silver oxide.

Assignees

• Conopco Inc

Inventors

• Chandar Prem
• Wu Guohui
• Kumar Nitish
• Manthena Vamsi Krishna
• Sanzgiri Vibhav Ramrao
• Shiloach Anat

Classifications

• A61P31/04

  Antibacterial agents · CPC title

• A61P17/00

  Drugs for dermatological disorders · CPC title

• C11D9/26

  containing oxygen {(C11D9/225 takes precedence)} · CPC title

• C11D3/48

  Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions · CPC title

• C11D17/08

  Liquid soap, {e.g. for dispensers}; capsuled · CPC title