Method for cleaning test sample wells, and cleaning head using said method

Patent metadata

Field	Value
Publication number	US-10144039-B2
Application number	US-201314395182-A
Country	US
Kind code	B2
Filing date	Apr 17, 2013
Priority date	Apr 19, 2012
Publication date	Dec 4, 2018
Grant date	Dec 4, 2018

Abstract

A method for cleaning a test sample well, provided in a diagnostic test card, using a cleaning head having a cleaning tube delivering, at its free end, a cleaning fluid, and a suction tube mounted inside the cleaning tube for aspirating the contaminated cleaning fluid from its free end located in proximity to the free end of the cleaning tube. The method provides for relative displacement between the test card and the cleaning head, so that the test card occupies a cleaning position wherein the cleaning tube delivers, at its free end, the cleaning fluid to the inside of the well to be cleaned and the suction tube aspirates the contaminated cleaning fluid.

First claim

The invention claimed is:

1. A method for cleaning at least one test sample well, provided in a diagnostic test card, using at least one cleaning head comprising at least one cleaning tube delivering, at its free end, a cleaning fluid, and a suction tube mounted within the cleaning tube for aspirating a contaminated cleaning fluid from its free end located in proximity to the free end of the cleaning tube, the method comprising:
providing a relative displacement between the test card and the cleaning head, so that the test card occupies a cleaning position wherein the cleaning tube delivers, at its free end, the cleaning fluid inside the sample well to be cleaned and the suction tube aspirates the contaminated cleaning fluid,
in the cleaning position, abutting the free end of the cleaning tube on the test card,
delivering the cleaning fluid from the free end of the cleaning tube along a delivery direction, in a direction of a transverse bottom wall of the sample well, and simultaneously aspirating the contaminated cleaning fluid with the aspiration tube,
thereby allowing an air intake between the outside and the inside of the free end of the cleaning tube, along a direction perpendicular to the delivery direction, thus creating a cleaning fluid vortex within the sample well when the contaminated cleaning fluid is aspirated.

2. The method according to claim 1 , wherein the free end of the cleaning tube is provided with a flexible tip which either delimits the air intake, or provides a seal with the test card when said tip is in abutment on the test card.

3. The method according to claim 1 , wherein the suction tube comprises a plurality of separate suction sections at its free end.

4. The method according to claim 1 , wherein the free end of the cleaning tube has a transverse surface, and wherein abutting the free end of the cleaning tube on the test card, allows an air intake proximate to, or on, the transverse surface of the cleaning tube.

5. The method according to claim 1 , wherein the relative displacement between the test card and the cleaning head is provided to create the air intake.

6. The method according to claim 5 , comprising configuring the test card so that said test card creates the air intake when the free end of the cleaning tube is in abutment on the test card.

7. The method according to claim 1 , wherein abutting the free end of the cleaning tube on the test card creates a suction zone with a predetermined height between the free end of the suction tube and the bottom of the sample well.

8. The method according to claim 7 , comprising creating the suction zone with the predetermined height between the free end of the suction tube and the bottom of the well, wherein the free end of the suction tube protrudes with respect to the free end of the cleaning tube.

9. The method according to claim 7 , comprising creating the suction zone with the predetermined height between the free end of the suction tube and the bottom of the sample well, wherein a height difference exists between the free end of the cleaning tube and the free end of the suction tube with respect to the bottom of the sample well.

Assignees

• Biomerieux Sa

Inventors

• Foucault Frederic

Classifications

• G01N35/1004

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• B01L13/02

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• B01L2300/0838

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• B01L2300/0636

  Integrated biosensor, microarrays · CPC title

• B01L3/5027 Primary

  by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip · CPC title