Compounding device, system, kit, software, and method

Patent metadata

Field	Value
Publication number	US-10143985-B2
Application number	US-201514719936-A
Country	US
Kind code	B2
Filing date	May 22, 2015
Priority date	Apr 23, 2015
Publication date	Dec 4, 2018
Grant date	Dec 4, 2018

Abstract

An exemplary compounding system and device for mixing materials from at least two distinct material sources can include a housing, a first fluid line operationally connected to the housing and configured to transport a first volume of fluid per unit time to a final container, a second fluid line operationally connected to the housing and configured to transport a second volume of fluid per unit time to the final container. The device can also include a pump system including, a first pump configured to move a first volume of fluid through a first fluid line, and a second pump configured to move a second volume of fluid through the second fluid line. The pump system can also be configured such that the volume of fluid per unit time delivered by the first and second pumps is different, and/or where the first and second pumps have different head characteristics.

First claim

What is claimed is:

1. A compounding device for mixing materials from at least two distinct material sources, comprising:
a housing;
at least two distinct material sources;
a first fluid line operationally connected to the housing and configured to transport a first volume of fluid per unit time to a final container;
a second fluid line operationally connected to the housing and configured to transport a second volume of fluid per unit time to the final container, wherein the first volume of fluid per unit time is different from the second volume of fluid per unit time;
a manifold connected to the first fluid line and second fluid line and configured to be releasably attached to the housing; and
a pump system including,
a first pump configured to move the first volume of fluid through the first fluid line, and
a second pump configured to move the second volume of fluid through the second fluid line, wherein

the manifold is connected to the first fluid line at a location along the first fluid line between at least one of the two distinct material sources and the first pump.

2. The compounding device of claim 1 , wherein the first pump is configured to have a first pump head characteristic, and the second pump is configured to have a second pump head characteristic, and the first pump head characteristic is different from the second pump head characteristic, and the manifold is connected to the second fluid line at a location along the second fluid line between at least another of the two distinct material sources and the second pump.

3. The compounding device of claim 1 , wherein the first fluid line has a first cross-sectional flow area defined by a cross-section taken normal to a fluid pathway of the first fluid line, and the second fluid line has a second cross-sectional flow area defined by a cross-section taken normal to a fluid pathway of the second fluid line, wherein the first cross-sectional flow area is different from the second cross-sectional flow area.

4. The compounding device of claim 1 , wherein the first pump includes a micro rotor and the second pump includes a macro rotor.

5. The compounding device of claim 4 , wherein the first pump includes a micro stepper motor encoded for positional accuracy and connected to the micro rotor, and the second pump includes a macro stepper motor encoded for positional accuracy and connected to the macro rotor.

6. The compounding device of claim 5 , wherein the micro rotor and macro rotor are interchangeable with each other, and the macro rotor is configured for connection to the micro stepper motor, and the micro rotor is configured for connection to the macro stepper motor.

7. The compounding device of claim 4 , wherein the micro rotor includes a lower flange configured to support a first tube that comprises a portion of the first fluid line and the flange of the micro rotor configured to maintain the first tube in proper position with respect to the micro rotor and the housing, and the macro rotor includes a lower flange configured to support a second tube that comprises a portion of the second fluid line, and the flange of the macro rotor configured to maintain the second tube in proper position with respect to the macro rotor and the housing.

8. The compounding device of claim 4 , further comprising:
a controller configured to rotate the micro rotor at a first speed and the macro rotor at a second speed, wherein the first speed is different from the second speed.

9. The compounding device of claim 1 , further comprising:
a transfer set including at least a portion of both the first fluid line and the second fluid line;
at least three distinct material sources, each in fluid connection to the transfer set; and
a final container in fluid connection to at least one output port of the transfer set.

10. The compounding device of claim 1 , further comprising:
a transfer set including the manifold and at least a portion of both the first fluid line and the second fluid line, the manifold being located upstream of both the first pump and second pump, the manifold including a micro channel that forms a portion of the first fluid line, and the manifold including a macro channel that forms a portion of the second fluid line, wherein the micro channel and the macro channel are in fluid isolation with respect to each other.

11. The compounding device of claim 10 , wherein the micro channel includes a micro channel cross-sectional area defined by a cross-section taken normal to a fluid pathway through the micro channel, and the macro channel includes a macro channel cross-sectional area defined by a cross-section taken normal to a fluid pathway through the macro channel, wherein the micro channel cross-sectional area is smaller than the macro channel cross-sectional area.

12. The compounding device of claim 10 , wherein the micro channel includes a plurality of input valves, each of the input valves of the micro channel is configured for connection to one of the distinct material sources, and the macro channel includes a plurality of input valves, each of the input valves of the macro channel is configured for connection to a different one of the distinct material sources.

13. The compounding device of claim 12 , wherein at least one of the plurality of input valves in fluid connection with the micro channel is connected to a micro input tubing line, and at least one of the plurality of input valves in fluid connection with the macro channel is connected to a macro input tubing line, wherein a cross-sectional diameter of the micro input tubing line is smaller than a cross-sectional diameter of the macro input tubing line.

14. The compounding device of claim 13 , wherein at least one of the plurality of input valves in fluid connection with the micro channel is connected to a macro input tubing line.

15. The compounding device of claim 10 , wherein the macro channel of the manifold includes a macro exit port, and the micro channel of the manifold includes a micro exit port, and a cross-sectional diameter of the micro exit port is less than a cross-sectional diameter of the macro exit port.

16. The compounding device of claim 10 , wherein the transfer set includes a micro tubing line extending from the micro channel of the manifold to the first pump, and the transfer set includes a macro tubing line extending from the macro channel of the manifold to the second pump, and a cross-sectional diameter of the micro tubing line is less than a cross-sectional diameter of the macro tubing line.

17. A compounding system for mixing materials from at least two distinct material sources, comprising:
a pump system including a first pump and a second pump; and
a transfer set connected to the pump system, wherein
the transfer set includes a first fluid line and a second fluid line, and the first fluid line is in fluid isolation from the second fluid line, and the first pump has a first volumetric flow rate and the second pump has a second volumetric flow rate, where the first volumetric flow rate is different from the second volumetric flow rate, the transfer set including a manifold located upstream of the first pump and second pump, the manifold including at least one first input port and a first output port forming a portion of the first fluid line, and at least one second input port and a second output port forming a portion of the second fluid line.

18. The compounding system of claim 17 , wherein the manifold includes a micro channel that forms a portion of the first fluid line and a macro channel that forms a porti

Assignees

• Braun Medical Inc

Inventors

• Brown Michael Y
• Lane Benjamin R
• Mumpower Mariano

Classifications

• A61J3/002 Primary

  Compounding apparatus specially for enteral or parenteral nutritive solutions (bottling liquids B67C) · CPC title

• A61M39/223 Primary

  Multiway valves · CPC title

• B65B3/12

  mechanically, e.g. by pistons or pumps · CPC title

• A61M2039/229

  Stopcocks · CPC title

• A61J2200/70

  Device provided with specific sensor or indicating means · CPC title