Biocompatible hydrophilic compositions

Patent metadata

Field	Value
Publication number	US-10138576-B2
Application number	US-201414487134-A
Country	US
Kind code	B2
Filing date	Sep 16, 2014
Priority date	Jun 12, 2008
Publication date	Nov 27, 2018
Grant date	Nov 27, 2018

Abstract

Durable hydrophilic compositions comprising aliphatic polyester, an anionic surfactant, and in some embodiments, a carrier.

First claim

The invention claimed is:

1. A nonwoven web of fibers, wherein the fibers comprise a blend comprising:
at least one thermoplastic aliphatic polyester;
an alkyl, alkenyl, aralkyl, or alkaryl anionic surfactant incorporated in the polyester; wherein the surfactant is selected from the group consisting of alkyl sulfate, alkenyl sulfate, alkaryl sulfate, aralkyl sulfate, alkylalkoxylated sulfate, alkyl sulfonate, alkenyl sulfonate, alkaryl sulfonate, aralkyl sulfonate, alkylalkoxylated sulfonate, alkyl phosphonate, alkenyl phosphonate, alkaryl phosphonate, aralkyl phosphonate, alkyl phosphate, alkenyl phosphate, alkaryl phosphate, aralkyl phosphate, alkyl alkoxylated phosphate, di(C 8 -C 18 ) sulfosuccinate salts, C 8 -C 22 alkyl sarcosinate salts, C 8 -C 22 alkyl lactylate salts, and combinations thereof; wherein the surfactant is present in a concentration sufficient to make the nonwoven web durably hydrophilic and absorbent and instantaneously wettable; and
a surfactant carrier;
wherein the fibers are 20 micrometers or less in diameter;
wherein the surfactant is soluble in the carrier at greater than 10% by weight such that the surfactant and carrier form a visually transparent solution in a 1-cm path length glass vial when heated to 150° C.

2. The nonwoven web of claim 1 wherein the surfactant carrier is a liquid at 23° C.

3. The nonwoven web of claim 1 wherein the anionic surfactant has a melting point of less than 200° C.

4. The nonwoven web of claim 1 wherein the anionic surfactant is selected from the group consisting of di(C 8 -C 18 ) sulfosuccinate salts, C 8 -C 22 alkyl sarcosinate salts, alkyl alkoxylated phosphates, C 8 -C 22 alkyl lactylate salts, and combinations thereof.

5. The nonwoven web of claim 1 wherein the anionic surfactant is present in a total amount of at least 0.5 wt-% of the blend.

6. The nonwoven web of claim 5 wherein the anionic surfactant is present in an amount of at least 0.5% by weight and no greater than 8% by weight of the blend.

7. The nonwoven web of claim 1 wherein the web is instantaneously absorbent.

8. The nonwoven web of claim 1 wherein the thermoplastic aliphatic polyester is selected from the group consisting of one or more poly(lactic acid), poly(glycolic acid), poly(lactic-co-glycolic acid), polybutylene succinate, polyhydroxybutyrate, polyhydroxyvalerate, blends, and copolymers thereof.

9. The nonwoven web of claim 1 wherein the surfactant carrier is selected from the group consisting of polyalkylene glycols, polyhydric alcohols, glycerin triglcyerides, citric acid esters, aliphatic diesters, and combinations thereof.

10. The nonwoven web of claim 1 wherein the nonwoven web is selected from the group consisting of a spunbond web, a blown microfiber web, and a hydroentangled web.

11. The nonwoven web of claim 1 wherein the surfactant is soluble in the carrier at greater than 10% by weight such that the surfactant and carrier form a visually transparent solution in a 1-cm path length glass vial at less than 100° C.

12. An article comprising a non-woven web of fibers, wherein the fibers comprise a blend comprising:
at least one thermoplastic aliphatic polyester present in a concentration of at least 75%, wherein the thermoplastic aliphatic polyester is selected from the group consisting of one or more poly(lactic acid), poly(glycolic acid), poly(lactic-co-glycolic acid), polybutylene succinate, polyhydroxybutyrate, polyhydroxyvalerate, blends, and copolymers thereof; and
a phosphate surfactant incorporated into the polyester, wherein the phosphate is selected from the group consisting of alkyl, alkaryl, alkenyl or aralkyl phosphates, and alkyl alkoxylated phosphates; wherein the phosphate surfactant is present in a concentration sufficient to make the nonwoven web durably hydrophilic and absorbent and instantaneously wettable;
wherein the fibers are 20 micrometers or less in diameter;
wherein the nonwoven is a blown microfiber web.

13. The article of claim 12 , wherein the phosphate has one of the following structures:
(R—O) 2 P(O)O − M + or R—OP(O)(O − ) 2 M +2

wherein:
R=alkyl or alkylene of C8-C30 which is branched or straight chain, or C12-C30 aralkyl, and may be optionally substituted with 0-100 alkylene oxide groups; and
M=an alkali metal salt or an amine salt.

14. The article of claim 12 , wherein the phosphate is present in an amount no greater than 8% by weight of the composition, and wherein the anionic surfactant is present in an amount of at least 0.5% by weight of the composition.

15. The article of claim 12 , wherein the fibers further comprise a surfactant carrier and wherein the surfactant carrier is present in an amount no greater than 8% by weight of the composition.

16. The article of claim 12 , wherein the fibers further comprise an antimicrobial component.

17. The article of claim 12 , wherein the article is a surgical drape or a surgical gown.

18. The article of claim 12 , wherein the article is a wound contact material or a personal hygiene article.

19. The article of claim 12 , further comprising a layer bonded to the non-woven web of fibers.

20. The article of claim 19 , wherein the layer is thermally bonded to the non-woven web of fibers.

21. The article of claim 19 , wherein the layer is adhesively bonded to the non-woven web of fibers.

22. The article of claim 19 , wherein the layer comprises a polymeric film.

23. The article of claim 19 , wherein the layer comprises a woven or non-woven web.

24. The nonwoven web of claim 1 , wherein the aliphatic polyester comprises greater than 75 wt % of the fibers.

25. The article of claim 12 , wherein the aliphatic polyester comprises greater than 75 wt % of the fibers.

Assignees

• 3M Innovative Properties Co

Inventors

• Scholz Matthew T
• Porbeni Francis E
• Jennen Jay M
• Karls Korey W

Classifications

• A61B46/40

  Drape material, e.g. laminates; Manufacture thereof · CPC title

• B29C39/003

  characterised by the choice of material · CPC title

• C08K5/42

  Sulfonic acids; Derivatives thereof · CPC title

• C08L2666/18

  Polyesters or polycarbonates according to C08L67/00 - C08L69/00; Derivatives thereof · CPC title

• Y10T442/681

  Spun-bonded nonwoven fabric · CPC title