Short-wave infrared super-continuum lasers and similar light sources for imaging applications

Patent metadata

Field	Value
Publication number	US-10136819-B2
Application number	US-201815888052-A
Country	US
Kind code	B2
Filing date	Feb 4, 2018
Priority date	Dec 31, 2012
Publication date	Nov 27, 2018
Grant date	Nov 27, 2018

Abstract

An imaging device includes laser diodes (LDs) generating near-infrared wavelength light, lenses configured to deliver the light to tissue, a first receiver having one or more detectors, and a first part with at least one of the LDs capable of being pulsed. The first receiver receives light reflected from the tissue and is synchronized to the pulsed light and configured to perform a time-of-flight measurement. An infrared camera receives light reflected by the tissue from a second part of the imaging device. The camera captures light while the second part is off, and while the second part is on to generate corresponding signals, and differences the signals to generate an image. An array of LDs generates a grid of spots on the tissue, which is reflected to the camera. A coupled phone, tablet, or computer receives and processes the time-of-flight measurement, the image, and the reflected grid of spots.

First claim

What is claimed is:

1. An imaging device, comprising:
a first part of the imaging device comprising a first at least one of a plurality of laser diodes, the first at least one of the plurality of laser diodes configured to be pulsed;
a second part of the imaging device comprising a second at least one of the plurality of laser diodes;
the plurality of laser diodes configured to generate light having one or more optical wavelengths, wherein at least a portion of the one or more optical wavelengths is a near-infrared wavelength between 700 nanometers and 2500 nanometers;
a first one or more lenses configured to receive at least a portion of the light from the plurality of laser diodes and to direct at least the portion of the light to tissue;
an array of laser diodes configured to generate light formed as a plurality of spots, the light having one or more optical wavelengths, wherein at least a portion of the one or more optical wavelengths is a near-infrared wavelength between 700 nanometers and 2500 nanometers;
a second one or more lenses configured to receive at least a portion of the light from the array of laser diodes and to direct at least the portion of the light from the array of laser diodes to tissue;
a first receiver comprising one or more detectors;
the first receiver configured to receive at least a portion of light reflected from the tissue from the first one of the plurality of laser diodes, wherein the first receiver is configured to be synchronized to the at least one of the plurality of pulsed laser diodes and is configured to perform a time-of-flight measurement;
an infrared camera configured to receive at least a portion of light from the second one of the plurality of laser diodes reflected from the tissue;
the infrared camera configured to:
generate a first signal while the plurality of laser diodes and the array of laser diodes are off; and
generate a second signal while the second part of the imaging device is on and the first part of the imaging device and the array of laser diodes are off, the second signal based at least in part on a portion of the light from the second part of the imaging device reflected from the tissue;
wherein the infrared camera is configured to difference the first signal and the second signal to generate a two-dimensional or three-dimensional image;

the imaging device coupled to one of a smart phone, tablet, or computer, the smart phone, tablet, or computer comprising a wireless receiver, a wireless transmitter, a display, a voice input module, and a speaker, the smart phone, tablet, or computer configured to receive and to process at least a portion of the time-of-flight measurement, the two-dimensional or three-dimensional image, and the received light from the plurality of spots reflected from the tissue.

2. The device of claim 1 wherein the first at least one of the plurality of laser diodes and the second at least one of the plurality of laser diodes comprise the same laser diode or diodes.

3. The device of claim 1 , wherein the array of laser diodes is configured to generate the plurality of spots by using an assembly in front of the array of laser diodes.

4. The device of claim 1 , wherein the one or more lenses configured to receive and to direct the portion of the light from the array of laser diodes comprises a cylindrical lens in front of the array of laser diodes.

5. The device of claim 1 , wherein the first receiver further comprises one or more filters in front of the one or more detectors to select a fraction of the one or more optical wavelengths.

6. The device of claim 1 , wherein the first at least one of the plurality of laser diodes configured to be pulsed has a modulation frequency, and wherein the first receiver is configured to use a lock-in technique that detects the modulation frequency.

7. The device of claim 6 , wherein the first receiver is configured to perform narrow band filtering at the modulation frequency.

8. The device of claim 6 , wherein the modulation frequency has a phase, and wherein the first receiver is configured to lock onto the phase.

9. An imaging device, comprising:
a first part comprising a first at least one of a plurality of laser diodes, the at least a first one of the plurality of laser diodes configured to be pulsed;
a second part comprising a second at least one of the plurality of laser diodes;
the plurality of laser diodes configured to generate light having one or more optical wavelengths, wherein at least a portion of the one or more optical wavelengths is a near-infrared wavelength between 700 nanometers and 2500 nanometers;
a first one or more lenses configured to receive at least a portion of light from the plurality of laser diodes and to direct the at least a portion of the light to tissue;
an array of laser diodes configured to generate light formed as a plurality of spots, the light having one or more optical wavelengths, wherein at least a portion of the one or more optical wavelengths is a near-infrared wavelength between 700 nanometers and 2500 nanometers;
a second one or more lenses configured to receive at least a portion of the light from the array of laser diodes and to direct the at least a portion of the light from the array of laser diodes to tissue;
a first receiver comprising one or more detectors;
the first receiver configured to receive at least a portion of light reflected from the tissue from the at least first one of the plurality of laser diodes, wherein the first receiver is configured to perform a time-of-flight measurement by measuring a time difference between the generated light from the first at least one of the plurality of laser diodes and light reflected from the tissue from the first at least one of the plurality of laser diodes;
an infrared camera configured to receive at least a portion of the light from the second one of the plurality of laser diodes reflected from the tissue and to generate a two-dimensional or three-dimensional image;
the imaging device coupled to one of a smart phone, tablet, or computer, the smart phone, tablet, or computer comprising a wireless receiver, a wireless transmitter, a display, a voice input module, and a speaker, the smart phone, tablet, or computer configured to receive and to process at least a portion of the time-of-flight measurement, the two-dimensional or three-dimensional image, and the received light from the plurality of spots reflected from the tissue.

10. The device of claim 9 , wherein the infrared camera is further configured to:
generate a first signal while the plurality of laser diodes and the array of laser diodes are off; and
generate a second signal while the second part is on and the first part and the array of laser diodes are off, the second signal based at least in part on a portion of the light from the second part reflected from the tissue;
wherein the infrared camera is further configured to difference the first signal and the second signal to generate the two-dimensional or three-dimensional image.

11. The device of claim 9 , wherein the one or more lenses configured to receive and to direct a portion of the light from the array of laser diodes comprises a cylindrical lens in front of the array of laser diodes.

12. The device of claim 9 , wherein the first receiver further comprises one or more filters in front of the one or more detectors to select a fraction of the one or more optical wavelengths.

13. The device of claim 9 , wherein the at least first one of the plurality of laser diodes configured to be pulsed has a modulation frequency, and wherein the first receiver is configured to use a lock-in technique that detects the

Assignees

• Omni Medsci Inc

Inventors

• Islam Mohammed N

Classifications

• G16H40/67

  for remote operation · CPC title

• A61B2562/0238

  Optical sensor arrangements for performing transmission measurements on body tissue · CPC title

• G01J3/108

  for measurement in the infrared range · CPC title

• A61B5/1455

  using optical sensors, e.g. spectral photometrical oximeters · CPC title

• G01N21/39

  using tunable lasers · CPC title