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Polymeric nanogels with degradable backbones and from gras components, and compositions and methods thereof
US10131745B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10131745-B2 |
| Application number | US-201715841388-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 14, 2017 |
| Priority date | Sep 9, 2014 |
| Publication date | Nov 20, 2018 |
| Grant date | Nov 20, 2018 |
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- Title
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Abstract
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The invention generally relates to novel polymers and polymeric nanogels having biodegradable polymeric backbones, and compositions and methods of preparation and use thereof, for example, as guest-host polymer nano-assemblies and nano-delivery vehicles, which offer utilities in diverse fields including drug delivery, diagnostics and specialty materials.
First claim
Opening claim text (preview).
What is claimed is: 1. A crosslinked biodegradable copolymer comprising the structural units of: wherein each of x and y is independently a positive number, and n is an integer from about 1 to about 8. 2. The crosslinked biodegradable polymer of claim 1 , wherein the copolymeric backbone is biodegradable into small molecules in response to a relevant biological, physical or chemical stimuli. 3. The crosslinked biodegradable polymer of claim 1 , wherein the small molecules that are generally regarded as safe (GRAS). 4. The crosslinked biodegradable polymer of claim 1 , wherein the copolymer is a random copolymer. 5. The crosslinked biodegradable polymer of claim 1 , wherein the copolymer is a block copolymer. 6. The crosslinked biodegradable polymer of claim 1 , wherein the copolymer comprises the structural unit of: 7. A polymeric nanogel comprising the crosslinked biodegradable polymer of claim 1 .
Assignees
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Classifications
Alpha-amino-carboxylic acids {(polysuccinimides C08G73/1092)} · CPC title
derived from polyamines and polycarboxylic acids · CPC title
obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides · CPC title
- C08G69/48Primary
Polymers modified by chemical after-treatment · CPC title
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Frequently asked questions
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- What does patent US10131745B2 cover?
- The invention generally relates to novel polymers and polymeric nanogels having biodegradable polymeric backbones, and compositions and methods of preparation and use thereof, for example, as guest-host polymer nano-assemblies and nano-delivery vehicles, which offer utilities in diverse fields including drug delivery, diagnostics and specialty materials.
- Who is the assignee on this patent?
- Univ Massachusetts
- What technology area does this patent fall under?
- Primary CPC classification C08G69/48. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Nov 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).