Vasopressin-2 receptor agonists

Patent metadata

Field	Value
Publication number	US-10131692-B2
Application number	US-201414647357-A
Country	US
Kind code	B2
Filing date	Jul 25, 2014
Priority date	Jul 26, 2013
Publication date	Nov 20, 2018
Grant date	Nov 20, 2018

Abstract

Vasopressin-2 receptor agonists, pharmaceutical compositions thereof and methods for using the foregoing for treating diabetes insipidus, primary nocturnal enuresis, and nocturia.

First claim

The invention claimed is:

1. A compound of the following formula:

or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition, comprising:
a pharmaceutically acceptable carrier; and
a compound of the following formula:

 or a pharmaceutically acceptable salt thereof.

3. A method of treating one of diabetes insipidus, primary nocturnal enuresis, and nocturia, comprising administering a therapeutically effective amount of a compound of claim 1 to a patient in need thereof.

Assignees

• Ferring Bv

Inventors

• Wisniewski Kazimierz
• Schteingart Claudio
• Riviere Pierre

Classifications

• A61P43/00

  Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00 · CPC title

• A61P5/10

  of the posterior pituitary hormones, e.g. oxytocin, ADH · CPC title

• A61P13/02

  of urine or of the urinary tract, e.g. urine acidifiers · CPC title

• A61P13/00

  Drugs for disorders of the urinary system · CPC title

• C07K7/54 Primary

  with at least one abnormal peptide link in the ring · CPC title