Microfluidic device and control equipment for microfluidic device

Patent metadata

Field	Value
Publication number	US-10130948-B2
Application number	US-201514894364-A
Country	US
Kind code	B2
Filing date	Apr 28, 2015
Priority date	Sep 15, 2014
Publication date	Nov 20, 2018
Grant date	Nov 20, 2018

Abstract

Provided is a microfluidic device to more easily and mechanically operate a valve for controlling a fluid flow, which comprises: a platform having a plurality of chambers; at least one flow channel which connects between the chambers; and a valve which opens or closes the flow channel, wherein the valve includes a blocking member which selectively blocks the flow channel and a pressing member installed in the blocking member to move the blocking member, and the pressing member has a structure which presses and moves the blocking member by the linear reciprocating motion in the same direction as the direction of an external force, and the valve further includes a driving unit which reversibly controls the opening and closing of the flow channel caused by the blocking member by fixing the pressing member to the position of the moved pressing member or returning to the original position.

First claim

What is claimed is:

1. A microfluidic device comprising:
a platform having a plurality of chambers; at least one flow channel which connects between the chambers; and a valve which opens or closes the flow channel,
wherein the valve includes a blocking member which selectively blocks the flow channel and a pressing member installed in the blocking member to move the blocking member, and
the pressing member has a structure which presses and moves the blocking member by a linear reciprocating motion in a same direction as a direction of an external force, and
the valve further includes a driving unit which reversibly controls the opening and closing of the flow channel caused by the blocking member by fixing the pressing member to a position of the moved pressing member or returning to an original position, and
the driving unit has a structure which selectively positions the pressing member to any one of a first position for blocking the flow channel or a second position for opening the flow channel, and
the driving unit includes a fixing unit to fix the position of the pressing member moved to the first position or the second position by an external force, and a returning unit to move the pressing member to the original position, and
the fixing unit includes a housing located outside of the blocking member, in which the pressing member is installed to be movable; a push bar connected to an outer front end of the pressing member and extending outside of the housing, in which the external force is applied; a first hole and a second hole formed on the housing along a direction of movement of the pressing member at a distance from each other, which define the first position or second position; an elastic bar installed in the push bar to be elastically deformable; and a projection protruding from the elastic bar, which is selectively hung at the first hole or the second hole.

2. The microfluidic device of claim 1 ,
wherein the blocking member has a structure made of a material having elasticity, and which opens and closes the flow channel by being pressed and transformed by the pressing member.

3. The microfluidic device of claim 1 ,
wherein the returning unit includes an elastic member installed between the housing and the push bar in the housing, which applies an elastic force to the push bar.

4. The microfluidic device of claim 1 ,
wherein the returning unit has a structure which moves the pressing member by applying an elastic force generated by being pressed and transformed by the pressing member in the blocking member to the pressing member.

5. The microfluidic device of claim 3 ,
wherein the push bar has a marker according to a push position in an outside surface.

6. A microfluidic device comprising
a platform having a plurality of chambers; at least one flow channel which connects between the chambers; and a valve which opens or closes the flow channel,
wherein the valve includes a blocking member which selectively blocks the flow channel and a pressing member installed in the blocking member to move the blocking member, and
the pressing member has a structure which presses and moves the blocking member by a linear reciprocating motion in a same direction as a direction of an external force, and
the valve further includes a driving unit which reversibly controls the opening and closing of the flow channel caused by the blocking member by fixing the pressing member to a position of the moved pressing member or returning to an original position, and
the driving unit has a structure which selectively positions the pressing member to any one of a first position for blocking the flow channel or a second position for opening the flow channel, and
the driving unit includes a fixing unit to fix the position of the pressing member moved to the first position or the second position by an external force, and a returning unit to move the pressing member to the original position, and
wherein the fixing unit includes a support tank located outside of the blocking member, in which the pressing member is installed to be movable; a rotation tank connected to the outer front end of the pressing member and installed in the support tank to be rotatable; a push bar installed by surrounding the outer front end of the rotation tank, in which an external force is applied by being extended to the outside of the support tank; a peg protruded at a distance along an outer peripheral surface of the rotation tank; a first locking groove and a second locking groove which define the first position and the second position by being arranged alternately along an inner peripheral surface of the support tank and by being formed at a distance along the direction of movement of the pressing member, in which the peg is selectively hung; an inclined plane moving member connected with an upper end of the peg by being formed along an inner front end of the push bar, which makes an inclined surface between the first locking groove and the second locking groove to alternately move the peg to the first locking groove and the second locking groove along the inclined surface when the push bar is pressed by the external force.

7. The microfluidic device of claim 6 ,
wherein the returning unit includes an elastic member installed between the support tank and the rotation tank in the support tank, which applies an elastic force to the rotation tank.

8. The microfluidic device of claim 6 ,
wherein the returning unit has a structure which moves the rotation tank by applying an elastic force generated by being pressed and transformed by the pressing member in the blocking member to the pressing member.

9. The microfluidic device of claim 7 ,
wherein the push bar has a marker according to a push position in an outside surface.

Assignees

• Ulsan Nat Inst Science & Tech Unist

Inventors

• Cho Yoon-Kyoung
• Kim Tae-Hyeong
• Kim Yu Bin

Classifications

• B01L2200/143

  Quality control, feedback systems · CPC title

• F16K99/0026

  Valves using channel deformation · CPC title

• F16K99/0034

  Operating means specially adapted for microvalves · CPC title

• B01L2300/123

  Flexible; Elastomeric · CPC title

• B01L3/502738 Primary

  characterised by integrated valves (throttle valves in microfluidic sample containers B01L3/502746) · CPC title