Anti-inflammatory compositions

Patent metadata

Field	Value
Publication number	US-10130652-B2
Application number	US-201113699248-A
Country	US
Kind code	B2
Filing date	May 23, 2011
Priority date	May 24, 2010
Publication date	Nov 20, 2018
Grant date	Nov 20, 2018

Abstract

The present invention relates to the use as an anti-inflammatory of tamarind seed polysaccharide (TSP) and to anti-inflammatory compositions which contain it as active ingredient. Anti-inflammatory compositions containing TSP are particularly useful for topical administration in the treatment of inflammatory diseases of the skin and mucosa.

First claim

The invention claimed is:

1. A method of treating inflammatory diseases comprising:
administering between 0.2% and 1% (w/w) of Tamarind seed polysaccharide in combination with between 0.2% and 1% (w/w) of an extract of Ferula hermonis in the total composition to a patient in need thereof,
wherein said inflammatory diseases comprise dermatitis, mucositis or stomatits.

2. The method of claim 1 for topical administration.

3. An anti-inflammatory pharmaceutical and/or dermocosmetic composition comprising between 0.2% and 1% (w/w) of tamarind seed polysaccharide in combination with between 0.2% and 1% (w/w) of an extract of Ferula hermonis in the total composition as active ingredients mixed with one or more acceptable excipients.

4. A composition according to claim 3 , for topical administration.

5. A composition according to claim 3 , in the form of cream, ointment, gel, lotion, gum, toothpaste, mouthwash or shampoo.

6. A composition according to claim 3 , comprising at least a further active ingredient selected from the group consisting of antimicrobial agents, anti-inflammatory agents, analgesic agents and wound-healing agents.

7. A composition according to claim 3 , further comprising between 0.2% and 1% (w/w) an extract of Aesculus hippocastanum in the total composition.

8. A method of treating a patient having an inflammatory disease comprising administering between 0.2% and 1% (w/w) of Tamarind see polysaccharide in combination with between 0.2% and 1% (w/w) of an extract of Ferula hermonis in the total composition, wherein said inflammatory disease comprises dermatitis, mucositis or stomatitis.

9. An anti-inflammatory pharmaceutical and/or dermocosmetic composition comprising about 0.2% (w/w) tamarind seed polysaccharide in combination with about 0.2% (w/w) of an extract of Ferula hermonis in the total composition as active ingredients mixed with one or more acceptable excipients.

Assignees

• Giori Andrea
• Arpini Sabrina
• Togni Stefano
• Indena Spa

Inventors

• Giori Andrea
• Arpini Sabrina
• Togni Stefano

Classifications

• A61P31/00

  Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics · CPC title

• A61P29/00

  Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title

• A61P17/00

  Drugs for dermatological disorders · CPC title

• A61K31/715 Primary

  Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters · CPC title

• A61K36/28

  Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea · CPC title