Dentifrice compositions having dental plaque mitigation or improved fluoride uptake

Patent metadata

Field	Value
Publication number	US-10130569-B2
Application number	US-201514634969-A
Country	US
Kind code	B2
Filing date	Mar 2, 2015
Priority date	May 15, 2014
Publication date	Nov 20, 2018
Grant date	Nov 20, 2018

Abstract

Dentifrice compositions with high water, a calcium-containing abrasive, an alkaline pH and minimal or nil amounts of polyols, such as PEG humectants, provide improved anti-plaque benefits.

First claim

What is claimed is:

1. A dentifrice composition comprising:
(a) 45% to 75% water by weight of the composition;
(b) 25% to 50% of a calcium-containing abrasive by weight of the composition; and
(c) 0.0025% to 2% of sodium monofluorophosphate by weight of the composition;
(d) from 0.01% to less than 1.4% carrageenan;
(e) a pH modifying agent selected from the group consisting of alkali metal hydroxides, ammonium hydroxide, organic ammonium compounds, carbonates, sesquicarbonates, borates, silicates, phosphates, imidazole, and combinations thereof;
(f) from 1% to 4% of a polyethylene glycol wherein the polyethylene glycol comprises an average molecular weight from 100 to 1600 Daltons;
(g) said composition having a pH greater than 9; and
wherein the composition is substantially free of a humectant selected from glycerin and sorbitol.

2. The composition of claim 1 , wherein the composition is also substantially free of a polyol other than said glycerin or sorbitol.

3. A composition according to claim 1 wherein the abrasive is calcium carbonate.

4. The composition of claim 1 further comprising 0.01% to 0.11 by weight of a paraben.

5. The composition of claim 4 , wherein the paraben is selected from methyl paraben, propyl paraben, or combinations thereof.

6. A dentifrice composition according to claim 5 further comprising:
27% to 37% of a calcium-containing abrasive by weight of the composition;
from 0.5% to 1.3% of a carrageenan by weight of the composition;
from 0.6% to 1.8% of a carboxymethyl cellulose (CMC) by weight of the composition.

7. The composition of claim 6 , further comprising 0.5% to 5% of a thickening silica by weight of the composition.

8. The composition of claim 6 further comprising from 0.5% to 1.5% by weight of sodium monofluorophosphate.

9. The composition of claim 6 , further comprising 0.1% to 12% by weight of sodium lauryl sulfate.

10. A method of treating tooth enamel comprising the step of brushing teeth with a dentifrice composition of claim 1 .

11. A method of mitigating plaque formation on tooth enamel comprising the step of brushing teeth with a dentifrice composition of claim 6 .

12. The composition of claim 1 comprising from 50% to 70%, by weight of the composition, water.

13. The composition of claim 12 comprising from 55% to 65%, by weight of the composition, water.

14. The composition of claim 1 wherein the pH is 9.4 to 9.6.

15. The composition of claim 1 wherein the pH is 9.4.

16. A dentifrice composition comprising:
(a) 50% to 60% water by weight of the composition;
(b) 27% to 37% of a calcium-containing abrasive by weight of the composition; and
(c) 0.0025% to 2% of sodium monofluorophosphate by weight of the composition;
(d) from 0.6% to less than 1.8% carrageenan;
(e) from 2% to 9% of an anionic surfactant;
(f) a pH modifying agent selected from the group consisting of alkali metal hydroxides, ammonium hydroxide, organic ammonium compounds, carbonates, sesquicarbonates, borates, silicates, phosphates, imidazole, and combinations thereof;
(g) said composition having a pH from 9 to 10; and
wherein the composition is substantially free of a humectant selected from glycerin and sorbitol.

17. A dentifrice composition comprising:
(a) 50% to 60% water by weight of the composition;
(b) 27% to 37% of a calcium-containing abrasive by weight of the composition; and
(c) 0.0025% to 2% of sodium monofluorophosphate by weight of the composition;
(d) from 0.6% to less than 1.8% carrageenan;
(e) from 2% to 9% of an anionic surfactant;
(f) from 1% to 3% of a polyethylene glycol wherein the polyethylene glycol comprises an average molecular weight from 400 to 800 Daltons;
(f) a pH modifying agent selected from the group consisting of alkali metal hydroxides, ammonium hydroxide, organic ammonium compounds, carbonates, sesquicarbonates, borates, silicates, phosphates, imidazole, and combinations thereof;
(g) said composition having a pH from 9 to 10; and
wherein the composition is substantially free of a humectant selected from glycerin and sorbitol.

Assignees

• Procter & Gamble

Inventors

• Chen Haijing
• Strand Ross
• White Jr Donald James
• Yang Hongmei

Classifications

• A61K8/463

  containing sulfuric acid derivatives, e.g. sodium lauryl sulfate · CPC title

• A61K8/37

  Esters of carboxylic acids · CPC title

• A61K8/19 Primary

  containing inorganic ingredients · CPC title

• A61K2800/92

  Oral administration · CPC title

• A61K2800/28

  Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants · CPC title