Hydrogels comprising cell adhesive peptides and methods of use thereof
US-2024376438-A1 · Nov 14, 2024 · US
US10123862B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10123862-B2 |
| Application number | US-201313803335-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 14, 2013 |
| Priority date | Mar 14, 2013 |
| Publication date | Nov 13, 2018 |
| Grant date | Nov 13, 2018 |
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An implantable structure, method for making the structure and method for using the structure, where the structure includes a combination of non-absorbable and absorbable components, and the implantable structure has a randomly uniform array of materials. The resulting implantable structure provides improved tissue ingrowth and flexibility after implantation and after absorption of the absorbable materials.
Opening claim text (preview).
What is claimed is: 1. An implantable material comprising a substantially uniform woven fabric woven from a first yarn including at least a previously kinked first non-absorbable filament and a second yarn including at least a first absorbable filament having a lower melting point than said first non-absorbable filament, wherein the substantially uniform woven fabric is randomly buckled throughout so as to exist in a random three dimensional shape, and wherein said implantable material includes a plurality of random points in three dimensional space at which said first absorbable filaments have been melted and thereby thermally bonded to the un-melted first yarn to thereby maintain said implantable material in said random three dimensional shape. 2. The implantable material according to claim 1 , wherein said first or second yarn further comprises a second absorbable filament, and said first or second yarn further comprises a second non-absorbable filament. 3. The implantable material of claim 1 , wherein said first non-absorbable filament is polypropylene and said first absorbable filament is polydioxanone. 4. The implantable material of claim 2 , wherein said first absorbable filament is polyglactin, said second absorbable filament is polydioxanone, and said first non-absorbable filament is polypropylene. 5. The implantable material of claim 1 , wherein said implantable material has a thickness of about 0.01-0.125 inches. 6. The implantable material of claim 1 , wherein said first absorbable filament comprises polyglactin and said first non-absorbable filament comprises polypropylene. 7. The implantable material of claim 6 , wherein said first or second yarn further comprises a second absorbable filament, and wherein said second absorbable filament is polydioxanone.
Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials} · CPC title
Porous materials, {e.g. foams or sponges} · CPC title
with macromolecular fillers · CPC title
synthetic threads · CPC title
obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds · CPC title
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