Substituted guanidines as fungicides

Patent metadata

Field	Value
Publication number	US-10111437-B2
Application number	US-201615576425-A
Country	US
Kind code	B2
Filing date	Jun 3, 2016
Priority date	Jun 3, 2015
Publication date	Oct 30, 2018
Grant date	Oct 30, 2018

Abstract

A novel guanidine compound having excellent fungicidal activity is represented by formula [I]. (In the formula, Y represents a divalent group represented by formula [II] (wherein each of R 7 -R 9 independently represents a hydrogen atom or the like) or the like; each of X and Z independently represents an unsubstituted or substituted alkylene group or the like; each of Q 1 and Q 2 independently represents a single bond or the like; each of A 1 and A 2 independently represents an unsubstituted or substituted divalent heterocyclic compound residue or the like; and each of R 1 -R 6 independently represents a hydrogen atom or the like.)

First claim

The invention claimed is:

1. A compound of formula [I]:

or a salt thereof,
wherein:
A 1 represents heterocyclyl, arylene optionally substituted with C 1-6 alkyl or halogeno, or —N(H)—;
A 2 represents heterocyclyl, arylene optionally substituted with C 1-6 alkyl or halogeno, or —N(H)—;
Q 1 represents a single bond, phenylene, —CH═CH—, —C≡C—, —O—, —S —, —S(O)—, —S(O) 2 —, or —N(H)—;
Q 2 represents a single bond, phenylene, —CH═CH—, —C≡C—, —O—, —S —,S(O)—, —S(O) 2 —, or —N(H)—;
X represents alkylene, alkenylene, alkynylene, -T a -O-T b , -T a -S-T b , or -T a -N(H)-T b -;
Z represents alkylene, alkenylene, alkynylene, -T a -O-T b , -T a -S-T b , or -T a -N(H)-T b -;
T a represents a single bond or alkylene optionally substituted with C 1-6 alkyl, halogeno, or oxo;
T b represents a single bond or alkylene optionally substituted with C 1-6 alkyl, halogeno, or oxo;
R 7 represents hydrogen or hydrocarbon;
R 8 represents hydrogen or hydrocarbon; and
R 9 represents hydrogen or hydrocarbon; or
R 8 and R 9 , bonded together, form a divalent organic group; or
R 8 and a substituent on X, bonded together, form a divalent organic group.

2. A fungicide comprising, as an active ingredient thereof, at least one selected from a compound of formula [I]:

or a salt thereof,
wherein:
A 1 represents heterocyclyl, arylene optionally substituted with C 1-6 alkyl or halogeno, or —N(H)—;
A 2 represents heterocyclyl, arylene optionally substituted with C 1-6 alkyl or halogeno, or —N(H)—;
Q 1 represents a single bond, phenylene, —CH═CH—, —C≡C—, —O—, —S —, —S(O)—, —S(O) 2 —, or —N(H)—;
Q 2 represents a single bond, phenylene, —CH═CH—, —C≡C—, —O—, —S —,S(O)—, —S(O) 2 —, or —N(H)—;
X represents alkylene, alkenylene, alkynylene, -T a -O-T b , -T a -S-T b , or -T a -N(H)-T b -;
Z represents alkylene, alkenylene, alkynylene, -T a -O-T b , -T a -S-T b , or -T a -N(H)-T b -;
T a represents a single bond or alkylene optionally substituted with C 1-6 alkyl, halogeno, or oxo;
T b represents a single bond or alkylene optionally substituted with C 1-6 alkyl, halogeno, or oxo;
R 7 represents hydrogen or hydrocarbon;
R 8 represents hydrogen or hydrocarbon; and
R 9 represents hydrogen or hydrocarbon; or
R 8 and R 9 , bonded together, form a divalent organic group; or
R 8 and a substituent on X, bonded together, form a divalent organic group.

3. A plant disease-controlling agent comprising, as an active ingredient thereof, at least one selected from a compound of formula [I]:

or a salt thereof,
wherein:
A 1 represents heterocyclyl, arylene optionally substituted with C 1-6 alkyl or halogeno, or —N(H)—;
A 2 represents heterocyclyl, arylene optionally substituted with C 1-6 alkyl or halogeno, or —N(H)—;
Q 1 represents a single bond, phenylene, —CH═CH—, —C≡C—, —O—, —S —, —S(O)—, —S(O) 2 —, or —N(H)—;
Q 2 represents a single bond, phenylene, —CH═CH—, —C≡C—, —O—, —S —,S(O)—, —S(O) 2 —, or —N(H)—;
X represents alkylene, alkenylene, alkynylene, -T a -O-T b , -T a -S-T b , or -T a -N(H)-T b -;
Z represents alkylene, alkenylene, alkynylene, -T a -O-T b , -T a -S-T b , or -T a -N(H)-T b -;
T a represents a single bond or alkylene optionally substituted with C 1-6 alkyl, halogeno, or oxo;
T b represents a single bond or alkylene optionally substituted with C 1-6 alkyl, halogeno, or oxo;
R 7 represents hydrogen or hydrocarbon;
R 8 represents hydrogen or hydrocarbon; and
R 9 represents hydrogen or hydrocarbon; or
R 8 and R 9 , bonded together, form a divalent organic group; or
R 8 and a substituent on X, bonded together, form a divalent organic group.

Assignees

• Nippon Soda Co

Inventors

• Ihori Yoichi
• INOUE Shuuji
• Shibayama Kotaro
• KANG Chang-Kyung
• Shiinoki Yasuyuki
• KAMADA Takuya
• Naito Hiroaki
• Nishimura Satoshi

Classifications

• C07D401/14

  containing three or more hetero rings · CPC title

• C07C279/12

  being further substituted by nitrogen atoms not being part of nitro or nitroso groups · CPC title

• C07D333/22

  Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom · CPC title

• C07D237/14

  Oxygen atoms · CPC title

• A01N51/00

  Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds having the sequences of atoms O—N—S, X—O—S, N—N—S, O—N—N or O-halogen, regardless of the number of bonds each atom has and with no atom of these sequences forming part of a heterocyclic ring · CPC title