Intergenic RNAS and methods for modulating gene expression and pathogenesis in candida

US10106790B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10106790-B2
Application numberUS-201515513312-A
CountryUS
Kind codeB2
Filing dateSep 18, 2015
Priority dateSep 22, 2014
Publication dateOct 23, 2018
Grant dateOct 23, 2018

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  1. Title

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  2. Abstract

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  5. First independent claim

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Abstract

Official abstract text for this publication.

Intergenic non-coding RNA molecules that regulate the expression of HWP1 and ALS3 of Candida are provided as are methods of using the non-coding RNA molecules and complementary molecules thereof in modulating HWP1 or ALS3 expression; adherence, yeast-to-hyphal transition, or biofilm development of Candida; and preventing or treating candidiasis.

First claim

Opening claim text (preview).

What is claimed is: 1. A recombinant vector expressing a nucleic acid molecule consisting of: (a) SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5 or SEQ ID NO:6; or (b) a nucleotide sequence complementary to a nucleotide sequence of (a).

Assignees

Inventors

Classifications

  • General methods for enhancing the expression · CPC title

  • Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression · CPC title

  • 2'-O-R Modification · CPC title

  • Phosphorothioates · CPC title

  • Gapmers, i.e. of the type ===---=== · CPC title

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What does patent US10106790B2 cover?
Intergenic non-coding RNA molecules that regulate the expression of HWP1 and ALS3 of Candida are provided as are methods of using the non-coding RNA molecules and complementary molecules thereof in modulating HWP1 or ALS3 expression; adherence, yeast-to-hyphal transition, or biofilm development of Candida; and preventing or treating candidiasis.
Who is the assignee on this patent?
Dartmouth College
What technology area does this patent fall under?
Primary CPC classification C12N15/113. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).