IV membrane attachment systems and methods

Patent metadata

Field	Value
Publication number	US-10105899-B2
Application number	US-201615078718-A
Country	US
Kind code	B2
Filing date	Mar 23, 2016
Priority date	Mar 26, 2015
Publication date	Oct 23, 2018
Grant date	Oct 23, 2018

Abstract

An intravenous delivery system may have a liquid source containing a liquid, tubing, and an anti-run-dry membrane positioned such that the liquid, flowing form the liquid source to the tubing, passes through the anti-run-dry membrane. The anti-run-dry membrane may be positioned within an exterior wall of a drip unit, and may have a weld surface secured to a seat of the exterior wall via application of compression to press the weld surface against the seat, and application of coherent light or vibration. In response to application of the coherent light or vibration, localized melting may occur, causing the weld surface to adhere to the seat. The anti-run-dry membrane may be modified to have a melting point close to that of the seat. Ultrasonic or laser welding may be applied in a manner that causes portions of the seat to melt and flow into pores of the weld surface.

First claim

We claim:

1. A method for manufacturing a drip unit for an intravenous delivery system, the method comprising:
providing an exterior wall shaped to at least partially define a drip chamber capable of receiving a liquid from a liquid source, the exterior wall comprising a seat;
providing an anti-run-dry membrane comprising a plurality of pores that are permeable to the liquid, wherein the anti-run-dry membrane is formed of a hydrophilic material configured to resist passage of air through the pores, the anti-run-dry membrane comprising a weld surface;
positioning the anti-run-dry membrane within the drip chamber such that the weld surface is in contact with the seat;
applying compression to press the weld surface against the seat;
applying at least one selection from the group consisting of coherent light and vibration to at least one of the anti-run-dry membrane and the exterior wall to cause localized melting of at least one of the seat and the weld surface; and
in response to the localized melting, causing the weld surface to adhere to the seat.

2. The method of claim 1 , wherein providing the anti-run-dry membrane comprises:
providing a hydrophilic material comprising a base material melting point;
performing a melting point reduction procedure on the hydrophilic material; and
forming the anti-run-dry membrane such that, due to performance of the melting point reduction procedure, the anti-run-dry membrane has a membrane melting point significantly lower than the base material melting point;
wherein the membrane melting point is within 20° C. of a wall melting point of the exterior wall.

3. The method of claim 2 , wherein performing the melting point reduction procedure comprises changing a chemical composition of a pre-polymer used to form the hydrophilic material to increase flexibility of a chemical structure of the pre-polymer.

4. The method of claim 2 , wherein performing the melting point reduction procedure comprises copolymerizing the hydrophilic material with an additive such that, in combination, the hydrophilic material and the additive have a combined chemical structure more flexible than a base chemical structure of the hydrophilic material.

5. The method of claim 2 , wherein performing the melting point reduction procedure comprises adding side branching to an aromatic ring structure of the hydrophilic material, thereby increasing flexibility of the aromatic ring structure.

6. The method of claim 1 , wherein the anti-run-dry membrane comprises a membrane melting point at least 20° C. higher than a wall melting point of the exterior wall, wherein causing the weld surface to adhere to the seat comprises:
causing flowable portions of the seat to enter the pores of the weld surface; and
permitting the flowable portions to solidify within the pores.

7. The method of claim 1 , wherein applying the compression comprises using a fixture to apply the compression, wherein applying the selection comprises, during application of the compression, applying the coherent light via a laser.

8. The method of claim 7 , wherein the coherent light comprises a wavelength greater than 2,000 nanometers.

9. The method of claim 7 , wherein applying the coherent light comprises:
directing the coherent light to a laser impingement area proximate a juncture between the seat and the weld surface; and
moving the laser impingement area along the juncture, in a closed pathway;
wherein causing the weld surface to adhere to the seat comprises causing the weld surface adhere to the seat along the pathway to provide a seal between the seat and the weld surface;
wherein the seal is positioned to cause fluid flowing from an upper part of the drip chamber to a lower part of the drip chamber to flow through the anti-run-dry membrane.

10. The method of claim 7 , wherein the exterior wall further comprises an opposing surface aligned with the seat and facing exterior to the exterior wall, wherein applying the coherent light via the laser comprises directing the coherent light at the seat through the opposing surface, along a direction substantially perpendicular to the opposing surface.

11. The method of claim 10 , wherein applying the coherent light comprises:
determining an optimal size of a laser impingement area proximate a juncture between the seat and the weld surface; and
determining a surface roughness level of the opposing surface that will cause the laser impingement area to have the optimal size;
wherein providing the exterior wall comprises forming the opposing surface with the surface roughness level;
wherein applying the coherent light comprises directing the coherent light to the laser impingement area, the laser impingement area.

12. The method of claim 7 , wherein the anti-run-dry membrane comprises a membrane component and a welding component having a substantially rigid construction, wherein the membrane component comprises the pores and the welding component comprises the weld surface.

13. The method of claim 1 , wherein applying the compression comprises using an ultrasonic welding horn to apply the compression, wherein applying the selection comprises, during application of the compression, applying the vibration via the ultrasonic welding horn.

14. The method of claim 13 , wherein the anti-run-dry membrane comprises a weld surface pore size of the pores proximate the weld surface, and a displaced pore size of the pores displaced from the weld surface, wherein the weld surface pore size is significantly larger than the displaced pore size.

15. The method of claim 13 , wherein providing the exterior wall comprises forming a first energy director on the seat, wherein the first energy director is shaped to protrude toward a location at which the anti-run-dry membrane will reside, relative to the exterior wall;
wherein positioning the anti-run-dry membrane within the drip chamber comprises positioning the weld surface in contact with the first energy director.

16. The method of claim 15 , wherein providing the exterior wall further comprises forming a second energy director on the seat, displaced from the first energy director such that the seat comprises a seat channel positioned between the first energy director and the second energy director, wherein the second energy director is shaped to protrude toward the location;
wherein positioning the anti-run-dry membrane within the drip chamber comprises positioning the weld surface in contact with the second energy director;
wherein the ultrasonic welding horn comprises a horn channel;
wherein using the ultrasonic welding horn to apply the compression comprises:
aligning the horn channel with the seat channel; and
urging the ultrasonic welding horn against the weld surface and the seat;

wherein causing the weld surface to adhere to the seat comprises causing a flowable portion of the weld surface to flow into the seat channel.

17. The method of claim 13 , wherein providing the exterior wall comprises providing the seat with a tapered shape comprising a leading edge, wherein using the ultrasonic welding horn to apply the compression comprises urging the ultrasonic welding horn against the leading edge;
wherein, during application of the vibration, the leading edge acts as an energy director by facilitating initiation of melt flow of the seat at the leading edge.

18. A method for manufacturing a drip unit for an intravenous delivery system, the method comprising:
providing an exterior wall shaped to at least partially define a drip chamber capable of receiving a liquid from a liquid

Assignees

• Becton Dickinson Co

Inventors

• Staley Shaun
• Hortin Justin G
• Stoddard Brent R
• Rivkowich Jason
• Trainer Lawrence J

Classifications

• B29C66/5344

  said single elements being substantially annular, i.e. of finite length, e.g. joining flanges to tube ends (B29C66/5346 takes precedence) · CPC title

• B29C65/08 Primary

  using ultrasonic vibrations {(non-plastics element to plastics elements B29C65/645)} · CPC title

• B29C66/81431

  comprising a single cavity, e.g. a groove · CPC title

• B29C66/73171

  Hydrophilicity · CPC title

• B29C66/232

  said joint lines being multiple and parallel, i.e. the joint being formed by several parallel joint lines · CPC title