Drive mechanism of a drug delivery device

Patent metadata

Field	Value
Publication number	US-10105498-B2
Application number	US-201414783496-A
Country	US
Kind code	B2
Filing date	Apr 8, 2014
Priority date	Apr 10, 2013
Publication date	Oct 23, 2018
Grant date	Oct 23, 2018

Abstract

A drug delivery device for dispensing of a dose of a medicament includes a housing extending in an axial direction and a piston rod to operably engage with a piston of a cartridge to displace the piston in an axial distal direction. The drug delivery device includes a dose indicating mechanism including a first spool and a second spool rotatably supported in the housing and a dose indicating tape coiled onto at least the second spool and fixed with an end to an outer circumference of the first spool. The first and second spools are oriented substantially parallel to each other and substantially parallel to the piston rod.

First claim

The invention claimed is:

1. A drug delivery device for dispensing a dose of a medicament, the drug delivery device comprising:
an elongate housing;
a cartridge arranged in the housing, the cartridge comprising the medicament and a piston to displace the medicament;
a piston rod configured to engage the piston to displace the piston in a distal direction along a longitudinal axis of the housing;
a dose indicating mechanism comprising a first spool and a second spool rotatably supported in the housing, the first spool and the second spool being oriented substantially parallel to each other and substantially parallel to the piston rod;
a dose indicating tape having a first end fixed to an outer circumference of the first spool and a second end fixed to an outer circumference of the second spool, the dose indicating tape being coiled onto at least the second spool; and
a drive sleeve coaxial, along the longitudinal axis, with the piston rod, the drive sleeve being selectively engageable with a user-operable dose setting member and selectively engageable with a user-operable dose dispensing button.

2. The drug delivery device of claim 1 , wherein the drive sleeve is positioned between the first spool and the second spool such that the dose indicating tape extends across the drive sleeve, the drive sleeve being operable to set the dose of the medicament and being rotatable to displace the piston rod in the distal direction, wherein the drive sleeve comprises a gear wheel engaged with a gear wheel of the first spool such that the first spool is rotatably engaged with the drive sleeve.

3. The drug delivery device of claim 1 , wherein the first spool and the second spool are rotatable about axes substantially parallel to the longitudinal axis, and the longitudinal axis is between the axes.

4. A drive mechanism of a drug delivery device for dispensing a dose of a medicament, the drive mechanism comprising:
a piston rod configured to engage with a piston of a cartridge to displace the piston in a distal direction along a longitudinal axis of a housing of the drug delivery device;
a dose indicating mechanism comprising a first spool and a second spool configured to be rotatably supported in the housing, the first spool and the second spool being oriented substantially parallel to each other and substantially parallel to the piston rod when rotatably supported in the housing;
a dose indicating tape having a first end fixed to an outer circumference of the first spool and a second end fixed to an outer circumference of the second spool, the dose indicating tape being coiled onto at least the second spool; and
a drive sleeve coaxial, along the longitudinal axis, with the piston rod, the drive sleeve being selectively engageable with a user-operable dose setting member and selectively engageable with a user-operable dose dispensing button.

5. The drive mechanism of claim 4 , wherein the drive sleeve is operable to set the dose of the medicament to be ejected from the drug delivery device, the first spool being rotatably engaged with the drive sleeve.

6. The drive mechanism of claim 5 , wherein the drive sleeve is positioned between the first spool and the second spool such that the dose indicating tape extends across the drive sleeve.

7. The drive mechanism of claim 5 , wherein the first spool comprises a gear wheel engaged with a gear wheel of the drive sleeve.

8. The drive mechanism of claim 7 , wherein the gear wheel of the drive sleeve is distally offset from the dose indicating tape.

9. The drive mechanism of claim 7 , wherein the gear wheel of the first spool is directly engaged with the gear wheel of the drive sleeve.

10. The drive mechanism of claim 4 , further comprising a support member positioned between the first spool and the second spool, the support member configured to support the dose indicating tape, and the dose indicating tape extending from the first spool across the support member to the second spool.

11. The drive mechanism of claim 4 , wherein at least one of the first spool or the second spool comprises a bearing portion offset from the dose indicating tape along the longitudinal axis, the bearing portion being rotatably arranged in an axially extending bearing recess of the housing.

12. The drive mechanism of claim 11 , wherein at least one of the first spool or the second spool is axially constrained by the bearing recess and a proximal closure of the housing.

13. The drive mechanism of claim 11 , further comprising a spool spring positioned radially between the bearing portion and the bearing recess, wherein the second spool is rotatable in a dose incrementing direction against a biasing force of the spool spring and in a dose decrementing direction with the biasing force of the spool spring.

14. The drive mechanism of claim 13 , wherein the spool spring comprises a helical spring having a first end engaged with the housing and a second end engaged with the second spool.

15. The drive mechanism of claim 13 , wherein the second spool is hollow, and the spool spring is located inside of the second spool.

16. The drive mechanism of claim 15 , wherein the first spool and the second spool are rotatably supported on an insert fixable in the housing.

17. The drive mechanism of claim 4 , wherein the first spool and the second spool are rotatable about axes substantially parallel to the longitudinal axis, and the longitudinal axis is between the axes.

Assignees

• Sanofi Sa

Inventors

• Bayer Stefan
• Berning Daniel
• Blank Philippe
• Pelzer Wolfgang
• Wilden Björn

Classifications

• A61M5/3157

  Means providing feedback signals when administration is completed (A61M5/20 takes precedence) · CPC title

• A61M2005/3126

  Specific display means related to dosing · CPC title

• A61M2205/582

  by tactile feedback · CPC title

• A61M5/31553

  without axial movement of dose setting member · CPC title

• A61M2205/581

  by audible feedback · CPC title