Placental tissue grafts and improved methods of preparing and using the same
US-2016030633-A1 · Feb 4, 2016 · US
Micronized placental tissue compositions and methods of making and using the same
US10105398B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10105398-B2 |
| Application number | US-201414286623-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 23, 2014 |
| Priority date | Feb 14, 2011 |
| Publication date | Oct 23, 2018 |
| Grant date | Oct 23, 2018 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
Described herein are compositions composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.
First claim
Opening claim text (preview).
What is claimed: 1. A sterile pharmaceutical composition comprising a pharmaceutically acceptable fluid carrier and micronized placental tissue particles, said placental tissue particles consisting essentially of an amnion layer and a chorion layer, wherein the chorion layer is layered directly over the amnion layer, wherein the amnion layer has an exposed basement membrane and an exposed fibroblast layer, wherein the intermediate layer of said amnion layer has been substantially removed, wherein the epithelial layer of said amnion layer has been substantially removed, and wherein the micronized placental tissue particles are less than 500 μm. 2. The composition of claim 1 , wherein the pharmaceutically acceptable carrier comprises water, aqueous hyaluronic acid, saline, Ringer's solution, dextrose solution, Hank's solution, a buffer, or an nonaqueous vehicle. 3. The composition of claim 2 , wherein the buffer comprises a phosphate buffer, bicarbonate buffer, or Tris buffer. 4. The composition of claim 1 , wherein the composition is injectable. 5. The composition of claim 1 , wherein the composition is a liquid, gel or paste. 6. The composition of claim 1 , wherein the micronized placental tissue particles are dehydrated. 7. The composition of claim 1 , wherein the micronized placental tissue particles are from 25 μm to 150μm.
Assignees
Inventors
Classifications
Flowable or injectable implant compositions · CPC title
- A61K35/50Primary
Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells · CPC title
characterised by the function or physical properties of the final product, where no specific conditions are defined to achieve this (A61L27/3687, A61L27/3691 take precedence) · CPC title
Preparations for care of the skin · CPC title
subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US10105398B2 cover?
- Described herein are compositions composed of micronized placental components and pharmaceutical compositions thereof. The compositions have numerous medical applications. Methods for making and using the micronized compositions are also described herein.
- Who is the assignee on this patent?
- Mimedx Group Inc
- What technology area does this patent fall under?
- Primary CPC classification A61K35/50. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Oct 23 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 3 related publications on this page (citations in our corpus or others sharing the same primary CPC).