Method of treating patients with hepatorenal syndrome type 1
US-2024366710-A1 · Nov 7, 2024 · US
US10105093B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10105093-B2 |
| Application number | US-201214004768-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 15, 2012 |
| Priority date | Mar 18, 2011 |
| Publication date | Oct 23, 2018 |
| Grant date | Oct 23, 2018 |
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A device comprising: means for obtaining a parameter of a sample of body fluid from a user; means for using information provided by one or more sensors to calculate a measure of physical activity of the user; means for calculating a medicament dose using at least in part the measured parameter and the measure of physical activity of the user; and means for indicating the calculated medicament dose to the user.
Opening claim text (preview).
The invention claimed is: 1. A device comprising: a blood glucose measurement unit configured to obtain a glucose level of a sample of blood from a user in response to a trigger signal generated based on a user input; a determining unit configured to (a) use information provided by one or more sensors to determine a level of intensity of physical activity in each of plural consecutive time periods and to record a value for the determined level of intensity along with an indication of an associated time period in the storage unit, (b) use information provided by the one or more sensors to calculate a measure of physical activity of the user, and (c) calculate a medicament dose using at least the measured glucose level and the measure of physical activity of the user, and a time elapsed between an instance of physical activity and a current time and to afford a higher weight (i) to an instance of physical activity occurring more recently with respect to the current time, and (ii) to an instance of physical activity having a higher level of intensity such that the higher level of intensity results in a disproportionately greater increase in the weight afforded to the medicament dose than a respective recorded value of the determined level of intensity; and a display unit configured to indicate the calculated medicament dose to the user. 2. A device as claimed in claim 1 , wherein the determining unit is further configured to use at least one measure of physical activity intensity to calculate the medicament dose. 3. A device as claimed in claim 1 , wherein the determining unit is further configured to use a duration of physical activity to calculate the medicament dose. 4. A device as claimed in claim 3 , wherein the determining unit is configured to integrate the physical activity intensity with respect to time and to use the result of the integration to calculate the medicament dose. 5. A device as claimed in claim 1 wherein the one or more sensors include a pedometer and the measure of physical activity is a number of steps taken by the user within a predetermined period. 6. A device as claimed in claim 5 , wherein the pedometer is integrated with the device. 7. A device as claimed in claim 1 , wherein the one or more sensors include an accelerometer integrated with the device. 8. A device as claimed in claim 1 , wherein the device includes a communications receiver configured to receive information from external one or more sensors. 9. A device as claimed in claim 8 , wherein the device is configured to verify that information received using the communications receiver relates to a user registered with the device and to disregard information other than verified information when calculating the medicament dose. 10. A device as claimed in claim 8 , wherein the device is configured to receive information relating to heart rate and/or blood pressure of a user and to calculate the measure of physical activity by processing the heart rate and/or blood pressure information. 11. A device as claimed in claim 8 , wherein the device is configured to receive information relating to a number of steps taken by a user from an external pedometer and to calculate the measure of physical activity by processing the steps information. 12. A device as claimed in claim 8 , wherein the device is configured to receive information relating to work done by the user or power exerted by the user from an external ergometer and to calculate the measure of physical activity by processing the work done or power information. 13. A method of operating a device, the method comprising: obtaining a measure of a glucose level of a sample of blood from a user in response to a trigger signal generated based on a user input; using information provided by one or more sensors to determine a level of intensity of physical activity in each of plural consecutive time periods and to record the determined intensity information along with an indication of the associated time period in a storage unit; using information provided by the one or more sensors to calculate a measure of physical activity of the user; calculating a medicament dose using at least the measured parameter, the measure of physical activity of the user and a time elapsed between an instance of physical activity and a current time and affording a higher weight (i) to an instance of physical activity occurring more recently with respect to the current time, and (ii) to an instance of physical activity having a higher level of intensity such that the higher level of intensity results in a disproportionately greater increase in the weight afforded to the medicament dose than a respective recorded value of the determined level of intensity; and indicating the calculated medicament dose to the user.
for measuring glucose, e.g. by tissue impedance measurement · CPC title
combined with detection or measurement of physiological parameters, e.g. heart rate · CPC title
with portable devices, e.g. worn by the patient · CPC title
combined with drug delivery · CPC title
Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches · CPC title
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