Borosilicate glass for pharmaceutical container and glass tube for pharmaceutical container

Patent metadata

Field	Value
Publication number	US-10099956-B2
Application number	US-201515508133-A
Country	US
Kind code	B2
Filing date	Aug 25, 2015
Priority date	Sep 5, 2014
Publication date	Oct 16, 2018
Grant date	Oct 16, 2018

Abstract

A borosilicate glass for a pharmaceutical container having high appearance quality, particularly a small number of air lines, and a glass tube for a pharmaceutical container are provided. The borosilicate glass for a pharmaceutical container contains, in mass %, from 70.0 to 78.0% of SiO 2 , from 5.0 to 8.0% of Al 2 O 3 , from 5.0 to 12.0% of B 2 O 3 , from 0 to 4.0% of CaO, from 0 to 4.0% of BaO, from 4.0 to 8.0% of Na 2 O, from 0 to 5.0% of K 2 O and from 0.001 to 1.0% of SnO 2 .

First claim

The invention claimed is:

1. A borosilicate glass for a pharmaceutical container, comprising, in mass %, from 70.0 to 78.0% of SiO 2 , from 5.0 to 8.0% of Al 2 O 3 , from 5.0 to 12.0% of B 2 O 3 , from 0 to 4.0% of CaO, from 0 to 4.0% of BaO, from 4.0 to 8.0% of Na 2 O, from 0 to 5.0% of K 2 O, from 0.001 to 0.08% of SnO 2 , and from 0.01 to 0.5% Cl.

2. The borosilicate glass for a pharmaceutical container according to claim 1 , further comprising from 0.0001 to 0.04 mass % of Fe 2 O 3 .

3. The borosilicate glass for a pharmaceutical container according to claim 1 , which does not contain As 2 O 3 and Sb 2 O 3 .

4. The borosilicate glass for a pharmaceutical container according to claim 1 , wherein an amount of Sn ions eluted in a test solution is 1.0 ppm or less in a glass grains test method of a hydrolytic resistance test according to European Pharmacopoeia 7.0.

5. The borosilicate glass for a pharmaceutical container according to claim 1 , wherein an amount of 0.02 mol/L hydrochloric acid consumed per unit glass mass is 0.030 mL or less in a glass grains test method of a hydrolytic resistance test according to European Pharmacopoeia 7.0.

6. The borosilicate glass for a pharmaceutical container according to claim 1 , wherein a mass decrement per area is 1.0 mg/dm 2 or less in an acid resistance test according to DIN 12116.

7. The borosilicate glass for a pharmaceutical container according to claim 1 , having a working temperature of 1200° C. or lower.

8. The borosilicate glass for a pharmaceutical container according to claim 1 , having a liquidus viscosity of 10 4.5 dPa·s or more.

9. A glass tube for a pharmaceutical container, comprising a borosilicate glass for a pharmaceutical container according to claim 1 .

10. The borosilicate glass for a pharmaceutical container according to claim 1 , wherein the content of SnO 2 is from 0.001 to 0.05 mass %.

11. The borosilicate glass for a pharmaceutical container according to claim 1 , wherein the content of Cl is from 0.01 to 0.1 mass %.

12. A borosilicate glass for a pharmaceutical container, comprising, in mass %, from 70.0 to 78.0% of SiO 2 , from 5.0 to 8.0% of Al 2 O 3 , from 5.0 to 12.0% of B 2 O 3 , from 0 to 4.0% of CaO, from 0 to 4.0% of BaO, from 4.0 to 8.0% of Na 2 O, from 0 to 5.0% of K 2 O, from 0.001 to 0.08% of SnO 2 , and from 0.0001 to 0.04% of Fe 2 O 3 .

13. The borosilicate glass for a pharmaceutical container according to claim 12 , wherein the content of SnO 2 is from 0.001 to 0.05 mass %.

14. The borosilicate glass for a pharmaceutical container according to claim 12 , wherein the content of Cl is from 0.01 to 0.1 mass %.

Assignees

• Nippon Electric Glass Co

Inventors

• Choju Ken
• Kimura Miki
• Yamamoto Kazuyuki

Classifications

• A61J1/065

  Rigid ampoules, e.g. glass ampoules · CPC title

• C03C4/20

  for chemical resistant glass · CPC title

• A61J1/05

  for collecting, storing or administering blood, plasma or medical fluids {(multiple bags systems for separating or storing blood components A61M1/0209); Infusion or perfusion containers} · CPC title

• C03C3/091 Primary

  containing aluminium · CPC title

• C03C1/004

  Refining agents (refining C03B5/225) · CPC title