Drive mechanism for a drug delivery device

Patent metadata

Field	Value
Publication number	US-10099015-B2
Application number	US-201414783160-A
Country	US
Kind code	B2
Filing date	Apr 8, 2014
Priority date	Apr 10, 2013
Publication date	Oct 16, 2018
Grant date	Oct 16, 2018

Abstract

The present invention relates to a drive mechanism for a drug delivery device for dispensing of a dose of a medicament, and to a respective drug delivery device, wherein the drive mechanism comprises: —an elongated housing (30) extending in an axial direction (1, 2), —a piston rod (80) to operably engage with a piston (16) of a cartridge (14) to displace the piston (16) in axial distal direction (1), —a drive sleeve (60) extending in axial direction (1, 2) and being rotatably supported in the housing (30), —a dose setting member (40) rotatably supported on a side wall portion (31) of the housing (30) and being rotatable with respect to an axis (41) extending in radial direction (r), —wherein the drive sleeve (60) is operably releasable from the piston rod (80) and rotatably engageable with the dose setting member (40) for setting of the dose.

First claim

The invention claimed is:

1. A drive mechanism of a drug delivery device for dispensing of a dose of a medicament, the drive mechanism comprising:
an elongated housing extending in an axial direction;
a piston rod to operably engage with a piston of a cartridge to displace the piston in an axial distal direction;
a drive sleeve extending in the axial direction and being rotatably supported in the elongated housing; and
a dose setting member rotatably supported on a side wall portion of the elongated housing and being rotatable with respect to an axis extending in a radial direction relative to the axial direction, the dose setting member comprising a radially inwardly extending shaft relative to the elongated housing,
wherein the drive sleeve is operably releasable from the piston rod and rotatably engageable with the dose setting member via the radially inwardly extending shaft for setting of the dose, and
wherein the drive sleeve is displaceable in the axial direction between a proximal dose setting position and a distal dose injecting position for selectively and alternately engaging and disengaging with the piston rod and with the dose setting member.

2. The drive mechanism according to claim 1 , wherein the drive sleeve is operably engageable with the piston rod and operably releasable from the dose setting member for dispensing of the dose.

3. The drive mechanism according to claim 1 , further comprising a dose injection member at a proximal end of the elongated housing, wherein the dose injection member is displaceable in the axial direction between a proximal dose setting position and a distal dose injecting position and distally abuts with the drive sleeve for displacing the drive sleeve into the distal dose injecting position.

4. The drive mechanism according to claim 3 , wherein the dose injection member is rotatably fixed to the elongated housing and comprises a locking member to engage with the dose setting member when reaching the distal dose injecting position.

5. The drive mechanism according to claim 3 , wherein the drive sleeve is displaceable in the axial distal direction relative to the elongated housing against an action of a spring element axially acting between the drive sleeve and the elongated housing.

6. The drive mechanism according to claim 1 , wherein the dose setting member comprises a gearwheel to engage with a crown wheel of the drive sleeve when in a dose setting position.

7. The drive mechanism according to claim 1 wherein the radially inwardly extending shaft is a hollow shaft and further comprising a support member fixedly attached to the elongated housing and having a radially outwardly extending socket portion to support the hollow shaft of the dose setting member.

8. The drive mechanism according to claim 7 , wherein the support member further comprises an axially extending receptacle at a proximal end to slidably receive the dose injection member.

9. The drive mechanism according to claim 7 , wherein a last dose limiting member is arranged between the socket portion and the hollow shaft, wherein the last dose limiting member is threadedly engaged with the socket portion and is rotatably fixed and slidably displaceable relative to the hollow shaft.

10. The drive mechanism according to claim 9 , wherein the last dose limiting member is displaceable along the socket portion between a zero dose limiting stop and a last dose limiting stop radially extending from opposite end portions of the socket portion or the hollow shaft.

11. The drive mechanism according to claim 1 , wherein the drive sleeve is rotatably and axially slidably engaged with a dose indicating sleeve threadedly engaged with an inside of the elongated housing, wherein the dose indicating sleeve comprises at least one stop at one axial end to abut with a single dose limiting stop located on the inside of the elongated housing.

12. The drive mechanism according to claim 1 , wherein the drive sleeve is rotatably biased relative to the elongated housing by a helical spring extending around the drive sleeve.

13. The drive mechanism according to claim 1 , wherein the piston rod is threadedly engaged with a drive nut axially fixed to the elongated housing and being rotatably supported in the elongated housing, wherein the drive sleeve is rotatably engaged with the drive nut when in a dose injecting position and wherein the drive sleeve and the drive nut are disengaged when the drive sleeve is in a dose setting position.

14. A drug delivery device for dispensing of a dose of a medicament, the drug delivery device comprising:
a drive mechanism comprising:
an elongated housing extending in an axial direction;
a piston rod to operably engage with a piston of a cartridge to displace the piston in an axial distal direction;
a drive sleeve extending in the axial direction and being rotatably supported in the elongated housing; and
a dose setting member rotatably supported on a side wall portion of the elongated housing and being rotatable with respect to an axis extending in a radial direction relative to the axial direction, the dose setting member comprising a radially inwardly extending shaft relative to the elongated housing,
wherein the drive sleeve is operably releasable from the piston rod and rotatably engageable with the dose setting member via the radially inwardly extending shaft for setting of the dose, and
wherein the drive sleeve is displaceable in the axial direction between a proximal dose setting position and a distal dose injecting position for selectively and alternately engaging and disengaging with the piston rod and with the dose setting member; and

the cartridge at least partially filled with the medicament and being arranged in the elongated housing of the drive mechanism or in a cartridge holder fixed to the elongated housing.

15. The drug delivery device according to claim 14 , wherein the drive sleeve is operably engageable with the piston rod and operably releasable from the dose setting member for dispensing of the dose.

16. The drive mechanism according to claim 1 , wherein the radially inwardly extending shaft extends radially inwardly into the elongated housing.

17. The drive mechanism according to claim 1 , wherein the radially inwardly extending shaft comprises an outwardly extending toothed surface engageable with a crown wheel of the drive sleeve.

18. The drive mechanism according to claim 1 , wherein the dose setting member comprises an actuation wheel located outside the side wall portion of the elongated housing.

19. The drive mechanism according to claim 18 , wherein a diameter of the actuation wheel is larger than a diameter of the radially inwardly extending shaft.

Assignees

• Sanofi Sa

Inventors

• Bayer Stefan
• Berning Daniel
• Blank Philippe
• Pelzer Wolfgang
• Pfoser Michael
• Wilden Björn

Classifications

• A61M5/315 Primary

  Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod {or piston}; Appliances on the rod for facilitating dosing {; Dosing mechanisms} · CPC title

• A61M5/31563

  interacting with a displaceable stop member · CPC title

• A61M5/31585

  performed by axially moving actuator, e.g. an injection button · CPC title

• A61M5/31553

  without axial movement of dose setting member · CPC title

• A61M2205/581

  by audible feedback · CPC title