Method for manufacturing succinic acid

Patent metadata

Field	Value
Publication number	US-10093608-B2
Application number	US-201615743842-A
Country	US
Kind code	B2
Filing date	Jul 14, 2016
Priority date	Jul 14, 2015
Publication date	Oct 9, 2018
Grant date	Oct 9, 2018

Abstract

The invention pertains to a method for preparing succinic acid which comprises providing an aqueous magnesium succinate solution to an acidification step, wherein the magnesium succinate solution is acidified by the addition of hydrogen chloride, thereby obtaining an aqueous solution comprising succinic acid and magnesium chloride and subjecting the aqueous solution comprising succinic acid and magnesium chloride derived from the acidification step to a treatment step with active carbon followed by precipitating succinic acid from an aqueous mixture comprising succinic acid and magnesium chloride resulting from the active carbon treatment step in a precipitation step to form solid succinic acid. It has been found that the method according to the invention leads to succinic acid crystals with better properties than a comparable method wherein no active carbon treatment is used.

First claim

The invention claimed is:

1. A method for preparing succinic acid comprising the steps of:
providing an aqueous magnesium succinate solution to an acidification step, wherein the magnesium succinate solution is acidified by the addition of hydrogen chloride, thereby obtaining an aqueous solution comprising succinic acid and magnesium chloride;
subjecting an aqueous solution comprising succinic acid and magnesium chloride derived from the acidification step to a treatment step with active carbon;
precipitating succinic acid from an aqueous mixture comprising succinic acid and magnesium chloride resulting from the active carbon treatment step in a precipitation step to form solid succinic acid and a magnesium chloride solution;
separating the solid succinic acid from the magnesium chloride solution;
subjecting the magnesium chloride solution to a thermal decomposition at a temperature of at least 300° C., thereby decomposing the magnesium chloride to magnesium oxide and hydrogen chloride; and
recycling the hydrogen chloride generated in the thermal decomposition step to the acidification step.

2. The method of claim 1 , wherein the magnesium succinate solution provided to the acidification step has a magnesium succinate concentration of 5-50 wt. %.

3. The method of claim 1 , wherein the acidification step is carried out to a pH between 1 and 2.

4. The method of claim 1 , wherein the solution subjected to the carbon treatment has a succinic acid concentration of at least 10 wt. %.

5. The method of claim 4 , wherein the succinic acid concentration is at least 18 wt. % at a temperature at least 60° C.

6. The method of claim 1 , wherein the active carbon treatment is carried out by passing the solution through a column comprising active carbon, or by adding active carbon to the solution and mixing it through the medium followed by removing it.

7. The method of claim 1 , wherein the contacting time during the active carbon treatment is in the range 1 minute to 24hours.

8. The method of claim 1 , wherein the active carbon treatment is carried out at a temperature of 50-120° C.

9. The method of claim 2 , wherein the magnesium succinate solution provided to the acidification step has a magnesium succinate concentration of 15-40 wt. %.

10. The method of claim 4 , wherein the solution subjected to the carbon treatment has a succinic acid concentration of at least 15 wt. %.

11. A method for preparing succinic acid comprising the steps of:
subjecting a carbon source to a fermentation step to form succinic acid, in which the fermentation step comprises the steps of fermenting a carbon source by means of a micro-organism capable of producing succinic acid in a fermentation broth to form succinic acid and neutralizing at least part of the succinic acid by adding a magnesium base selected from magnesium oxide, magnesium hydroxide, magnesium carbonate, and magnesium bicarbonate, thereby obtaining a magnesium succinate solution;
providing the aqueous magnesium succinate solution, optionally after a biomass removal step and/or a concentration step, to an acidification step, wherein the magnesium succinate solution is acidified by the addition of hydrogen chloride, thereby obtaining an aqueous solution comprising succinic acid and magnesium chloride;
subjecting an aqueous solution comprising succinic acid and magnesium chloride derived from the acidification step to a treatment step with active carbon;
precipitating succinic acid from an aqueous mixture comprising succinic acid and magnesium chloride resulting from the active carbon treatment step in a precipitation step to form solid succinic acid and a magnesium chloride solution;
separating the solid succinic acid from the magnesium chloride solution;
subjecting the magnesium chloride solution to a thermal decomposition at a temperature of at least 300° C., thereby decomposing the magnesium chloride to magnesium oxide and hydrogen chloride; and
recycling the hydrogen chloride generated in the thermal decomposition step to the acidification step.

12. The method of claim 11 , wherein the magnesium succinate solution provided to the acidification step has a magnesium succinate concentration of 5-50 wt. %.

13. The method of claim 11 , wherein the acidification step is carried out to a pH between 1and 2.

14. The method of claim 11 , wherein the solution subjected to the carbon treatment has a succinic acid concentration of at least 10 wt. %.

15. The method of claim 14 , wherein the succinic acid concentration is at least 18 wt. % at a temperature at least 60° C.

16. The method of claim 11 , wherein the active carbon treatment is carried out by passing the solution through a column comprising active carbon, or by adding active carbon to the solution and mixing it through the medium followed by removing it.

17. The method of claim 11 , wherein the contacting time during the active carbon treatment is in the range 1 minute to 24 hours.

18. The method of claim 11 , wherein the active carbon treatment is carried out at a temperature of 50-120° C.

19. The method of claim 12 , wherein the magnesium succinate solution provided to the acidification step has a magnesium succinate concentration of 15-40 wt. %.

20. The method of claim 14 , wherein the solution subjected to the carbon treatment has a succinic acid concentration of at least 15 wt. %.

Assignees

• Purac Biochem Bv

Inventors

• Van Breugel Jan
• Jansen Peter Paul
• Vidal Lancis Jose Maria
• Dekic Zivkovic Tanja
• Kon Adriaan Dirk

Classifications

• C01F5/10

  by thermal decomposition of magnesium chloride with water vapour · CPC title

• C01F5/30

  Chlorides · CPC title

• C07C51/02 Primary

  from salts of carboxylic acids · CPC title

• C07C55/10 Primary

  Succinic acid · CPC title

• C07C51/43

  by change of the physical state, e.g. crystallisation · CPC title