Compositions and methods of making brittle-matrix particles through blister pack freezing

US10092512B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10092512-B2
Application numberUS-77879510-A
CountryUS
Kind codeB2
Filing dateMay 12, 2010
Priority dateFeb 13, 2008
Publication dateOct 9, 2018
Grant dateOct 9, 2018

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

The present invention includes compositions and methods for treating and delivering medicinal formulations using an inhaler. The composition includes a space filled flocculated suspension having one or more flocculated particles of one or more active agents and a hydrofluoroalkane propellant. A portion of the one or more flocculated particles is templated by the formation of hydrofluoroalkane droplets upon atomization and the templated floc compacts upon the evaporation of the hydrofluoroalkane propellant to form a porous particle for deep lung delivery.

First claim

Opening claim text (preview).

What is claimed is: 1. A unit-dose delivery system for use in a dry powder inhaler comprising: a unit-dose delivery system comprising one or more concave indentations; a cover positioned to sealed the one or more concave indentations; and a medicinal formulation of one or more active agents appropriate for pulmonary delivery in at least one of the one or more concave indentations, wherein the medicinal formulation comprises porous, matrix of nano-structured primary particles o…

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What does patent US10092512B2 cover?
The present invention includes compositions and methods for treating and delivering medicinal formulations using an inhaler. The composition includes a space filled flocculated suspension having one or more flocculated particles of one or more active agents and a hydrofluoroalkane propellant. A portion of the one or more flocculated particles is templated by the formation of hydrofluoroalkane d…
Who is the assignee on this patent?
Johnston Keith P, Engstrom Joshua, Rowe Jasmine, and 3 more
What technology area does this patent fall under?
Primary CPC classification A61K9/008. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Oct 09 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).