Local high-resolution imaging method for three-dimensional skeletal image and apparatus therefor

Patent metadata

Field	Value
Publication number	US-10089736-B2
Application number	US-201615331620-A
Country	US
Kind code	B2
Filing date	Oct 21, 2016
Priority date	Jul 14, 2016
Publication date	Oct 2, 2018
Grant date	Oct 2, 2018

Abstract

A local high-resolution imaging method and apparatus for a three-dimensional (3D) skeletal image is provided. The method includes determining a volume of interest (VOI) to perform high-resolution imaging from the 3D skeletal image in which an object to be inspected is captured, localizing the VOI based on a finite element method (FEM), and setting a multi-resolution constraint based on a bone mineral density (BMD) between the 3D skeletal image and the localized VOI and reconstructing a skeletal image in which high-resolution imaging is performed on the localized VOI.

First claim

What is claimed is:

1. A local high-resolution imaging method for a three-dimensional (3D) skeletal image by using a high-resolution imaging device, the method comprising:
determining a volume of interest (VOI) to perform high-resolution imaging on the 3D skeletal image in which an object to be inspected is captured by using a VOI determining unit of the high-resolution imaging device, wherein the VOI determining unit determines a partial specific portion to perform high-resolution imaging on the 3D skeletal image;
localizing the VOI based on a finite element method (FEM) by using a VOI localizing unit of the high-resolution imaging device, wherein the VOI localizing unit calculates a structural behavior value of each of finite elements for a locally provided load; and
setting a multi-resolution constraint based on a bone mineral density (BMD) between the 3D skeletal image and the localized VOI and reconstructing a skeletal image in which high-resolution imaging is performed on the localized VOI by using an image reconstructing unit of the high-resolution imaging device,

wherein the localizing of the VOI by using the VOI localizing unit comprises:
performing the FEM for the skeletal image in which the object to be inspected is captured;
extracting a displacement corresponding to a cut boundary of the VOI based on a previously defined load condition;
performing the FEM for the VOI by applying the extracted displacement to a boundary condition; and
extracting a reaction force corresponding to a cut boundary of the VOI in which the FEM is performed and setting the extracted reaction force as a local load condition.

2. The method of claim 1 , wherein the determining of the VOI comprises:
determining a plurality of VOIs on the skeletal image; and
verifying a trabecular bone corresponding to each of the VOIs based on a skeletal image, in which high-resolution imaging is performed, reconstructed for the plurality of VOIs.

3. A local high-resolution imaging method for a three-dimensional (3D) skeletal image by using a high-resolution imaging device, the method comprising:
determining a volume of interest (VOI) to perform high-resolution imaging on the 3D skeletal image in which an object to be inspected is captured by using a VOI determining unit of the high-resolution imaging device, wherein the VOI determining unit determines a partial specific portion to perform high-resolution imaging on the 3D skeletal image;
localizing the VOI based on a finite element method (FEM) by using a VOI localizing unit of the high-resolution imaging device, wherein the VOI localizing unit calculates a structural behavior value of each of finite elements for a locally provided load; and
setting a multi-resolution constraint based on a bone mineral density (BMD) between the 3D skeletal image and the localized VOI and reconstructing a skeletal image in which high-resolution imaging is performed on the localized VOI by using an image reconstructing unit of the high-resolution imaging device,

wherein the reconstructing of the skeletal image by using the image reconstructing unit in which the high-resolution imaging is performed comprises:
setting a separate voxel value in a high-resolution image as a design variable;
setting compliance of the VOI as an objective function indicating a strain energy of the VOI; and
setting a BMD difference between the high-resolution image and a low-resolution image as the multi-resolution constraint.

4. The method of claim 3 , wherein the high-resolution image is generated by subdividing a voxel of a low-resolution image corresponding to the VOI included in the 3D skeletal image.

5. The method of claim 4 , wherein the reconstructing of the skeletal image in which the high-resolution is performed comprises:
reconstructing a bone microstructure for the VOI by performing topology optimization for a finite element model corresponding to the high-resolution image.

6. A local high-resolution imaging apparatus for a 3D skeletal image, the apparatus comprising:
a memory into which at least one program is loaded, wherein the memory includes an operating system and a service routine; and
at least one processor comprising a VOI determining unit, a VOI localizing unit and an image reconstructing unit,
wherein the VOI determining unit of at least one processor determines a VOI to perform high-resolution imaging on the 3D skeletal image in which an object to be inspected is captured, wherein the VOI localizing unit localizes the VOI based on an FEM, and the image reconstructing unit sets a multi-resolution constraint based on a BMD between the 3D skeletal image and the localized VOI and reconstructs a skeletal image in which high-resolution imaging is performed on the localized VOI, under control of the at least one program,
wherein the VOI localizing unit performs the FEM for the skeletal image in which the object to be inspected is captured, extracts a displacement corresponding to a cut boundary of the VOI based on a previously defined load condition, performs the FEM for the VOI by applying the extracted displacement to a boundary condition, and extracts a reaction force corresponding to a cut boundary of the VOI in which the FEM is performed and sets the extracted reaction force as a local load condition.

7. A local high-resolution imaging apparatus for a 3D skeletal image, the apparatus comprising:
a processor, the processor includes a VOI determining unit configured to determine a VOI to perform high-resolution imaging on the 3D skeletal image in which an object to be inspected is captured, wherein the VOI determining unit determines a partial specific portion to perform high-resolution imaging on the 3D skeletal image;
the processor further includes a VOI localizing unit configured to localize the VOI based on an FEM, wherein the VOI localizing unit calculates a structural behavior value of each of finite elements for a locally provided load; and
the processor further includes an image reconstructing unit configured to set a multi-resolution constraint based on a BMD between the 3D skeletal image and the localized VOI and to reconstruct a skeletal image in which high-resolution imaging is performed on the localized VOI,
wherein the VOI localizing unit performs the FEM for the skeletal image in which the object to be inspected is captured, extracts a displacement corresponding to a cut boundary of the VOI based on a previously defined load condition, performs the FEM for the VOI by applying the extracted displacement to a boundary condition, and extracts a reaction force corresponding to a cut boundary of the VOI in which the FEM is performed and sets the extracted reaction force as a local load condition.

8. The apparatus of claim 7 , wherein the VOI determining unit determines a plurality of VOIs on the skeletal image and verifies a trabecular bone corresponding to each of the VOIs based on a skeletal image, in which high-resolution imaging is performed, reconstructed for the plurality of VOIs.

9. A local high-resolution imaging apparatus for a 3D skeletal image, the apparatus comprising:
a processor, the processor includes a VOI determining unit configured to determine a VOI to perform high-resolution imaging on the 3D skeletal image in which an object to be inspected is captured, wherein the VOI determining unit determines a partial specific portion to perform high-resolution imaging on the 3D skeletal image;
the processor further includes a VOI localizing unit configured to localize the VOI based on an FEM, wherein the VOI localizing unit calculates a structural behavior value of each of finite elements for a locally provided load; and
the processor further includes an image reconstructing unit con

Assignees

• Korea Advanced Inst Sci & Tech

Inventors

• Jang Ingwun
• Kim Jung Jin

Classifications

• G06T2219/2016

  Rotation, translation, scaling · CPC title

• G06T2207/20104

  Interactive definition of region of interest [ROI] · CPC title

• G06T19/20

  Editing of three-dimensional [3D] images, e.g. changing shapes or colours, aligning objects or positioning parts · CPC title

• G06T3/4053

  based on super-resolution, i.e. the output image resolution being higher than the sensor resolution · CPC title

• A61B6/5205

  involving processing of raw data to produce diagnostic data · CPC title