Process for the preparation of esters by means of carbonylation of ethers

Patent metadata

Field	Value
Publication number	US-10087134-B2
Application number	US-201715651062-A
Country	US
Kind code	B2
Filing date	Jul 17, 2017
Priority date	Jul 19, 2016
Publication date	Oct 2, 2018
Grant date	Oct 2, 2018

Abstract

The invention relates to a process comprising the process steps of:
a) initially charging an ether having from 3 to 30 carbon atoms; b) adding a phosphine ligand and a compound comprising Pd, or adding a comprising Pd and a phosphine ligand; c) feeding in CO; d) heating the reaction mixture, with conversion of the ether; wherein the phosphine ligand is a compound of formula (I)

where
m and n are each independently 0 or 1;
R 1 , R 2 , R 3 , R 4 are each independently selected from —(C 1 -C 12 )-alkyl, —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl, —(C 6 -C 20 )-aryl, —(C 3 -C 20 )-heteroaryl;
at least one of the R 1 , R 2 , R 3 , R 4 radicals is a —(C 3 -C 20 )-heteroaryl radical;
and
R 1 , R 2 , R 3 , R 4 , if they are —(C 1 -C 12 )-alkyl, —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl, —(C 6 -C 20 )-aryl or —(C 3 -C 20 )-heteroaryl,
may each independently be substituted by one or more substituents selected from —(C 1 -C 12 )-alkyl, —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl, —O—(C 1 -C 12 )-alkyl, —O—(C 1 -C 12 )-alkyl-(C 6 -C 20 )-aryl, —O—(C 3 -C 12 )-cycloalkyl, —S—(C 1 -C 12 )-alkyl, —S—(C 3 -C 12 )-cycloalkyl, —COO—(C 1 -C 12 )-alkyl, —COO—(C 3 -C 12 )-cycloalkyl, —CONH—(C 1 -C 12 )-alkyl, —CONH—(C 3 -C 12 )-cycloalkyl, —CO—(C 1 -C 12 )-alkyl, —CO—(C 3 -C 12 )-cycloalkyl, —N—[(C 1 -C 12 )-alkyl] 2 , —(C 6 -C 20 )-aryl, —(C 6 -C 20 )-aryl-(C 1 -C 12 )-alkyl, —(C 6 -C 20 )-aryl-O—(C 1 -C 12 )-alkyl, —(C 3 -C 20 )-heteroaryl, —(C 3 -C 20 )heteroaryl-(C 1 -C 12 )-alkyl, —(C 3 -C 20 )-heteroaryl-O—(C 1 -C 12 )-alkyl, —COOH, —SO 3 H, —NH 2 , halogen;
and wherein no alcohol is added to the reaction mixture.

First claim

The invention claimed is:

1. Process for preparing esters from ether precursor comprising:
a) forming a reaction mixture by initially charging an ether having from 3 to 30 carbon atoms;
b) adding a phosphine ligand and a compound comprising Pd, or adding a complex comprising Pd and a phosphine ligand;
c) feeding in CO;
d) heating the reaction mixture, formed by steps a)-c), performed in any order, with conversion of the ether; wherein the phosphine ligand is a compound of fo…

Assignees

• Evonik Degussa Gmbh

Inventors

• Dong Kaiwu
• Jackstell Ralf
• Neumann Helfried
• Beller Matthias
• Fridag Dirk
• Hess Dieter
• Dyballa Katrin Marie
• Geilen Frank
• Franke Robert

Classifications

• C07C67/62

  Chemistry & Metallurgy · mapped topic

• C07F9/58

  Chemistry & Metallurgy · mapped topic

• C07C67/37 Primary

  Chemistry & Metallurgy · mapped topic

• B01J27/13

  Operations & Transport · mapped topic

• C07C69/14

  Chemistry & Metallurgy · mapped topic