Synthesis and isolation of dendrimer based imaging systems
US-2015352230-A1 · Dec 10, 2015 · US
US10086091B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10086091-B2 |
| Application number | US-201615080165-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 24, 2016 |
| Priority date | Sep 27, 2013 |
| Publication date | Oct 2, 2018 |
| Grant date | Oct 2, 2018 |
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The present disclosure relates to a novel type of recognitive biodegradable nanoparticles and their preparations. In particular, the present disclosure relates to combinations of MIPs and biodegradable nanoparticles.
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What is claimed is: 1. A composition comprising an outer shell having at least one binding cavity specific for a target molecule and wherein the outer shell comprises poly(maleic anhydride-alt-1-octadecene)-g-poly(ethylene glycol) methacrylate (PMAO-g-PEGMA); and a biodegradable inner core comprising poly(ε-caprolactone) (PCL) and substantially free of the binding cavity. 2. The composition of claim 1 , further comprising an active agent. 3. The composition of claim 2 , wherein the active agent is a fluorophore, a therapeutic agent, or a hydrophobic agent.
on to unsaturated polyethers, polyoxymethylenes or polyacetals · CPC title
Polyesters, e.g. poly(lactide-co-glycolide) · CPC title
Nanoparticle, nanocapsule, nanobubble, nanosphere, nanobead, i.e. having a size or diameter smaller than 1 micrometer, e.g. polymeric nanoparticle · CPC title
obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides · CPC title
Macromolecular compounds, i.e. oligomers, polymers, dendrimers · CPC title
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