N-[1-((6-chloropyridin-3-yl)methyl)pyridin-2(1H)-ylidene]-2,2,2- trifluoroacetamide for control of agricultural/horticultural pests

Patent metadata

Field	Value
Publication number	US-10085449-B2
Application number	US-201715634284-A
Country	US
Kind code	B2
Filing date	Jun 27, 2017
Priority date	Aug 31, 2010
Publication date	Oct 2, 2018
Grant date	Oct 2, 2018

Abstract

A compound of formula (Ie′):

wherein Ar′, R 1 , R 4e and Y are as defined herein and a method of controlling pests using the compound.

First claim

The invention claimed is:

1. An amine derivative or salt thereof, wherein the amine derivative is N-[1-((6-chloropyridin-3-yl)methyl)pyridin-2(1H)-ylidene]-2,2,2-trifluoroacetamide, and exhibits a melting point of 155 to 158° C. in differential scanning calorimetry (DSC) measured in a temperature rise rate 10° C./min.

2. The amine derivative or salt thereof according to claim 1 , wherein the amine derivative has diffraction angle peaks at least at the following diffraction angles (2θ) in powder x-ray diffraction analysis measured using Cu-Kα as an X-ray source:
8.6±0.2°, 14.2±0.2°, 17.5±0.2°, 18.3±0.2°, 19.7±0.2°, 22.3±0.2°, 30.9±0.2°, 35.3±0.2°.

3. The amine derivative or salt thereof according to claim 1 , which has a pest control activity against at least one type of pest selected from the group consisting of agricultural/horticultural pests, animal parasitic pests, health pests, nuisance pests, stored grain pests, stored food pests and household pests.

4. The amine derivative or salt thereof according to claim 3 , which has a pest control activity against at least one type of pest selected from the group consisting of lepidopterous pests, hemipterous pests, thysanopterous pests, dipterous pests, coleopterous pests, animal parasitic fleas and ticks, and canine heartworms.

5. The amine derivative or salt thereof according to claim 4 , which has a pest control activity against at least one type of pest selected from the group consisting of diamondback moth, common cutworm, cotton aphid, green peach aphid, small brown planthopper, brown rice planthopper, white-backed rice planthopper, green rice leafhopper, greenhouse whitefly, western flower thrips, rice leaf bug, brown-winged green bug, rice leaf beetle, house fly, rice water weevil, and Haemaphysalis longicornis.

6. The amine derivative or salt thereof according to claim 4 , wherein the pest is a pesticide-resistant pest.

7. The amine derivative or salt thereof according to claim 5 , wherein the pest is a pesticide-resistant planthopper.

8. The amine derivative or a salt thereof according to claim 1 , wherein the amine derivative is in crystal form.

Assignees

• Meiji Seika Pharma Co Ltd

Inventors

• Kagabu Shinzo
• Mitomi Masaaki
• Kitsuda Shigeki
• Horikoshi Ryo
• Nomura Masahiro
• Onozaki Yasumichi

Classifications

• A61P33/00

  Antiparasitic agents · CPC title

• C07D213/36

  Radicals substituted by singly-bound nitrogen atoms (nitro radicals C07D213/26) · CPC title

• C07D277/32

  with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms · CPC title

• C07C261/04

  Cyanamides (unsubstituted cyanamide C01C3/16) · CPC title

• C07D401/12

  linked by a chain containing hetero atoms as chain links · CPC title