Dialysis solution, use of a dialysis solution and chemical compound

Patent metadata

Field	Value
Publication number	US-10076531-B2
Application number	US-201615175384-A
Country	US
Kind code	B2
Filing date	Jun 7, 2016
Priority date	Jun 16, 2015
Publication date	Sep 18, 2018
Grant date	Sep 18, 2018

Abstract

The present invention relates to a dialysis solution having at least one osmotic agent, wherein the osmotic agent is starch propylphosphonate.

First claim

The invention claimed is:

1. A dialysis solution having at least one osmotic agent, characterized in that the osmotic agent is starch propylphosphonate produced from starch having a number average molecular weight in the range from 3000 g/mol to 5000 g/mol.

2. A dialysis solution in accordance with claim 1 , characterized in that the dialysis solution contains exactly one kind of starch propylphosphonate or a plurality of kinds of starch propylphosphonates.

3. A dialysis solution in accordance with claim 1 , characterized in that the dialysis solution does not contain any further osmotic agent except for starch propylphosphonate.

4. A dialysis solution in accordance with claim 1 , characterized in that the starch propylphosphonate is completely water-soluble.

5. A dialysis solution in accordance with claim 1 , characterized in that the starch propylphosphonate has an average degree of substitution in the range from 0.1 to 1.2.

6. A dialysis solution in accordance with claim 5 , characterized in that the starch propylphosphonate has an average degree of substitution in the range from 0.2 to 0.5.

7. A dialysis solution in accordance with claim 1 , characterized in that the solution comprises electrolytes and a buffer.

8. A dialysis solution in accordance with claim 7 , characterized in that the electrolytes comprise the ions of sodium and/or potassium and/or calcium and/or magnesium.

9. A dialysis solution in accordance with claim 7 , characterized in that the buffer comprises lactate ions and/or hydrogen carbonate ions.

10. A method for dialysis, comprising utilizing the dialysis solution in accordance with claim 1 for the dialysis.

11. The method in accordance with claim 10 , characterized in that the dialysis is hemodialysis or hemodiafiltration.

12. A method in accordance with claim 10 , characterized in that the dialysis is peritoneal dialysis.

13. A chemical compound consisting of or comprising one or more water-soluble starch propylphosphonates.

14. A chemical compound in accordance with claim 13 , characterized in that
the starch propylphosphonate has an average degree of substitution in the range from 0.1 to 1.2.

15. The chemical compound of claim 13 , wherein said chemical compound consists of one or more starch propylphosphonates.

Assignees

• Fresenius Medical Care Deutschland Gmbh

Inventors

• Berlich Robert
• Schweitzer Thomas
• Finkler Lisa
• Heinze Thomas
• Hampe Robert

Classifications

• A61K31/662 Primary

  Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon · CPC title

• C08L3/06

  Esters · CPC title

• A61K33/00

  Medicinal preparations containing inorganic active ingredients · CPC title

• C08B31/066

  Starch phosphates, e.g. phosphorylated starch · CPC title

• A61K31/718

  Starch or degraded starch, e.g. amylose, amylopectin · CPC title