PREPARATION OF Ag18F AND ITS USE IN THE SYNTHESIS OF PET RADIOTRACERS
US-2016317682-A1 · Nov 3, 2016 · US
Copper catalyzed [18F]fluorination of iodonium salts
US10071943B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10071943-B2 |
| Application number | US-201515303087-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 10, 2015 |
| Priority date | Apr 11, 2014 |
| Publication date | Sep 11, 2018 |
| Grant date | Sep 11, 2018 |
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Abstract
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Copper-catalyzed radiofluorination of iodonium salts, iodonium salts, and compounds obtained by copper-catalyzed radiofluorination of iodonium salts are disclosed. Diagnostic and therapeutic methods involving such compounds also are disclosed.
First claim
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What is claimed is: 1. A method of preparing a radiolabeled aryl fluoride of Formula (2) comprising: reacting a diaryliodonium salt of Formula (1) with an 18 F source in the presence of a copper (I) source selected from CuOTf.toluene and (CH 3 CN) 4 CuOTf under conditions sufficient to form the radiolabeled aryl fluoride of Formula (2)…
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Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US10071943B2 cover?
- Copper-catalyzed radiofluorination of iodonium salts, iodonium salts, and compounds obtained by copper-catalyzed radiofluorination of iodonium salts are disclosed. Diagnostic and therapeutic methods involving such compounds also are disclosed.
- Who is the assignee on this patent?
- Univ Michigan Regents
- What technology area does this patent fall under?
- Primary CPC classification C07C41/22. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Sep 11 2018 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).