Oral care compositions

Patent metadata

Field	Value
Publication number	US-10071159-B2
Application number	US-201113982846-A
Country	US
Kind code	B2
Filing date	Jan 31, 2011
Priority date	Jan 31, 2011
Publication date	Sep 11, 2018
Grant date	Sep 11, 2018

Abstract

Described herein are compositions comprising an active compound from an extract of magnolia, or a derivative thereof; and a non-surfactant electrolyte in an amount effective to stabilize the composition, and methods of making and using the same.

First claim

What is claimed is:

1. An oral care composition comprising:
a liquid comprising a mixture of:
an antibacterial effective amount of an active compound from an extract of magnolia;
sodium sulfate at a concentration of about 2% by weight of the composition;
at least one fluoride ion source selected from: stannous fluoride, sodium fluoride, potassium fluoride, sodium monofluorophosphate, sodium fluorosilicate, ammonium fluorosilicate, amine fluoride, ammonium fluoride, and a combination of two or more thereof; and
an orally acceptable carrier,
wherein said liquid does not exhibit complete phase separation upon centrifuging at 500 rpm for 2 hours;
wherein the active compound is selected from honokiol, tetrahydromagnolol, and tetrahydrohonokiol, and mixtures thereof; and wherein the active compound is present at a concentration of about 1 to about 2% by weight of the composition.

2. The composition according to claim 1 , wherein the active compound is honokiol.

3. The composition according to claim 1 , wherein the active compound is present at a concentration of about 1 to about 1.5% by weight of the composition.

4. The composition according to claim 1 , wherein the active compound is present at a concentration of about 1.3%, by weight of the composition.

5. The composition according to claim 1 , wherein the composition is in a form selected from: a mouthrinse, toothpaste, a lozenge, a confectionary, and a dissolvable tablet.

6. The composition according to claim 1 , further comprising one or more components selected from: an abrasive, a surfactant, a foaming agent, a vitamin, a polymer, an enzyme, a humectant, a thickener, an antibacterial agent, a preservative, a flavoring agent and a colorant.

7. A method of treating a disease or condition of the oral cavity comprising contacting an oral cavity surface with a composition of claim 1 .

8. The method of claim 7 , wherein the disease or condition of the oral cavity is selected from gingivitis, periodontitis and halitosis.

Assignees

• Pillai Shyamala
• Fei Lin
• Xu Guofeng
• Colgate Palmolive Co

Inventors

• Pillai Shyamala
• Fei Lin
• Xu Guofeng

Classifications

• A61P1/02

  Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis · CPC title

• A61K8/19

  containing inorganic ingredients · CPC title

• A61K8/347

  Phenols · CPC title

• A61Q11/00

  Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title

• A61K31/105

  Persulfides (thiuram disulfides A61K31/145; thiosulfonic acids A61K31/185) · CPC title